Organic Letters,
Год журнала:
2024,
Номер
26(20), С. 4235 - 4239
Опубликована: Май 13, 2024
An
organic
dye
photocatalyzed
lactonization-alkynylation
of
easily
accessible
homoallylic
cesium
oxalates
using
ethynylbenziodoxolone
(EBX)
reagents
has
been
developed.
The
reaction
gave
access
to
valuable
functionalized
lactones
and
lactams
in
up
88%
yield
via
the
formation
two
new
C-C
bonds.
transformation
was
carried
out
on
primary,
secondary,
tertiary
alcohols
primary
amines
could
be
applied
synthesis
spirocyclic
compounds
as
well
fused
bridged
bicyclic
lactones.
Catalysts,
Год журнала:
2023,
Номер
13(9), С. 1243 - 1243
Опубликована: Авг. 26, 2023
The
functionalization
of
unactivated
substrates
through
the
combination
copper
catalysts
and
hypervalent
iodine
reagents
represents
a
versatile
tool
in
organic
synthesis
to
access
various
classes
compounds.
derivatives
can
be
used
simply
as
oxidizing
agents
regenerate
catalytic
species
or
they
associate
starting
material.
In
this
review,
special
attention
will
paid
methodologies
which
provide
introduction
nucleophiles
into
reagent
by
use
suitable
benziodoxol(on)es
iodonium
salts.
Many
reactions
concern
C-
N-arylations,
but
may
also
involve
formation
different
carbon–carbon
carbon–nitrogen
bonds,
carbon–oxygen
well
carbon–halogen
carbon–phosphorus
bonds.
Chemical Communications,
Год журнала:
2023,
Номер
59(84), С. 12637 - 12640
Опубликована: Янв. 1, 2023
Bis(trifluoromethylated)benziodoxoles
(Bx)
are
broadly
used
cyclic
hypervalent
iodine
reagents
due
to
their
stability
and
unique
chemical
properties.
However,
current
methods
access
them
require
several
steps
long
reaction
times,
making
synthesis
tedious.
Herein,
a
direct
one-pot
of
bis(trifluoromethylated)
Bx
from
iodine(I)
precursors
is
reported,
enabling
the
functionalized
reagents.
Beilstein Journal of Organic Chemistry,
Год журнала:
2024,
Номер
20, С. 701 - 713
Опубликована: Апрель 3, 2024
We
report
the
detailed
background
for
discovery
and
development
of
synthesis
homopropargylic
azides
by
azido-alkynylation
alkenes.
Initially,
a
strategy
involving
SOMOphilic
alkynes
was
adopted,
but
only
resulted
in
29%
yield
desired
product.
By
switching
to
radical-polar
crossover
approach
after
optimization,
high
(72%)
azide
reached.
Full
insights
are
given
about
factors
that
were
essential
success
optimization
process.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(21), С. 4326 - 4331
Опубликована: Янв. 1, 2024
A
viable
protocol
to
access
furo[3,2-
c
]chromen-4-ones
engaging
4-hydroxy
coumarins
and
thioamides
mediated
by
phenyliodine(
iii
)
diacetate
at
room
temperature
in
a
highly
efficient
manner
is
developed.
Organic Letters,
Год журнала:
2024,
Номер
26(20), С. 4235 - 4239
Опубликована: Май 13, 2024
An
organic
dye
photocatalyzed
lactonization-alkynylation
of
easily
accessible
homoallylic
cesium
oxalates
using
ethynylbenziodoxolone
(EBX)
reagents
has
been
developed.
The
reaction
gave
access
to
valuable
functionalized
lactones
and
lactams
in
up
88%
yield
via
the
formation
two
new
C-C
bonds.
transformation
was
carried
out
on
primary,
secondary,
tertiary
alcohols
primary
amines
could
be
applied
synthesis
spirocyclic
compounds
as
well
fused
bridged
bicyclic
lactones.
