Angewandte Chemie,
Год журнала:
2024,
Номер
136(14)
Опубликована: Янв. 5, 2024
Abstract
Mechanochemical
reactions
offer
methodological
and
environmental
advantages
for
chemical
synthesis,
constantly
attracting
attention
within
the
scientific
community.
Besides
unmistakable
sustainability
advantages,
conditions
under
which
mechanochemical
occur,
namely
solventless
conditions,
sometimes
facilitate
isolation
of
otherwise
labile
or
inaccessible
products.
Despite
these
limited
knowledge
exists
regarding
mechanisms
types
intermediates
involved.
Nevertheless,
in
an
expanding
number
cases,
ex
situ
monitoring
techniques
have
allowed
observation,
characterization,
reaction
transformations.
In
this
Minireview,
we
present
a
series
examples
reactive
been
detected
spanning
organic,
organometallic,
inorganic,
materials
chemistry.
Many
were
stabilized
by
non‐covalent
interactions,
played
pivotal
role
guiding
We
believe
that
uncovering
understanding
such
instances,
growing
mechanochemistry
community
could
find
novel
opportunities
catalysis
discover
new
while
achieving
simplification
design.
Green Chemistry,
Год журнала:
2024,
Номер
26(14), С. 8341 - 8347
Опубликована: Янв. 1, 2024
Resonant
Acoustic
Mixing
(RAM)
allows
High
Throughput
Experimentation
(HTE)
using
commercially
available
96-well
plates
as
exemplified
by
the
nickel
catalyzed
C–N
cross
coupling
of
aryl
halides
with
different
amine
and
anilines.
Chemistry - An Asian Journal,
Год журнала:
2024,
Номер
19(14)
Опубликована: Май 8, 2024
The
beginning
of
photochemical
reactions
revolutionized
synthetic
chemistry
through
sustainable
practices.
This
review
explores
cutting-edge
developments
in
leveraging
light-induced
processes
for
generating
cascaded
C-C
and
C-hetero
bonds
without
catalysts.
Significantly,
catalyst-free
photoinduced
methodologies
have
garnered
considerable
attention,
especially
the
creation
varied
heterocyclic
frameworks
drug
design
synthesis
natural
products.
article
delves
into
underlying
mechanisms,
addresses
limitations,
evaluates
various
methodologies,
emphasizing
potential
photocatalyst
transition
metal-free
to
enhance
sustainability.
Divided
two
sections,
it
covers
recent
strides
C-heteroatom
multiple
bond
formation
reactions.
European Journal of Organic Chemistry,
Год журнала:
2024,
Номер
27(30)
Опубликована: Май 18, 2024
Abstract
Mechanochemistry,
as
an
enabling
technology,
harnesses
mechanical
force
to
drive
chemical
reactions,
presenting
compelling
advantages
in
organic
synthesis
within
the
principles
of
green
chemistry.
This
review
explores
how
its
unique
and
alignment
with
sustainable
practices
have
been
widely
developed
different
scientific
fields
Italy.
As
a
transformative
strategy
for
synthesis,
mechanochemistry
has
portrayed
this
valuable
synthetic
alternative
due
various
advantages,
such
solvent
reduction
new
reaction
pathways,
that
use
brings.
Nonetheless,
improvements
brought
about
by
also
crucial
other
chemistry
described
Italian
scientists.
In
whole
context,
researchers
analysed
both
already
optimised
processes
feasible
paving
way
avenues
previously
hampered
all
limitations
belong
in‐solution
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(10), С. 5504 - 5504
Опубликована: Май 18, 2024
Molecularly
imprinted
polymers
(MIPs)
are
established
artificial
molecular
recognition
platforms
with
tailored
selectivity
towards
a
target
molecule,
whose
synthesis
and
functionality
highly
influenced
by
the
nature
of
solvent
employed
in
their
synthesis.
Steps
"greenification"
imprinting
technology
(MIT)
has
already
been
initiated
elaboration
green
MIT
principles;
developing
MIPs
solvent-free
environment
may
not
only
offer
an
eco-friendly
alternative,
but
could
also
significantly
influence
affinity
expected
resulting
binding
sites.
In
current
study
first
mechanochemical
via
liquid-assisted
grinding
(LAG)
is
reported.
The
successful
polymer
was
functionally
demonstrated
measuring
its
template
rebinding
capacity
process
comparison
ones
obtained
conventional,
non-covalent
liquid
media.
results
similar
capacities
molecule
superior
chemoselectivity
compared
to
solution-based
MIP
method.
adoption
chemistry
principles
all
inherent
advantages
be
able
alleviate
potential
environmental
health
concerns
associated
analytical
(e.g.,
selective
adsorbents)
biomedical
drug
carriers
or
reservoirs)
applications,
might
conceptual
change
technology.
Chemical Science,
Год журнала:
2023,
Номер
14(44), С. 12477 - 12483
Опубликована: Янв. 1, 2023
Iconic
Lappert's
heavier
tetrylenes
E{N(SiMe3)2}2
(E
=
Ge
(1),
Sn
(2),
Pb
(3))
have
been
efficiently
prepared
from
GeCl2·(1,4-dioxane),
SnCl2
or
PbCl2
and
Li{N(SiMe3)2}
via
a
completely
solvent-free
one-pot
mechanochemical
route
followed
by
sublimation.
This
fast,
high-yielding
scalable
approach
(2
has
in
100
mmol
scale),
which
involves
small
environmental
footprint,
represents
remarkable
improvement
over
any
synthetic
reported
the
last
five
decades,
being
so
far
rare
example
of
use
mechanochemistry
realm
main
group
chemistry.
solventless
successfully
extended
to
preparation
other
tetrylenes,
such
as
ECl{N(SiMe3)2}
(4),
(5)).
Dalton Transactions,
Год журнала:
2024,
Номер
53(9), С. 3990 - 3993
Опубликована: Янв. 1, 2024
Ball
milling
of
5-,
6-,
and
7-membered
N-heterocyclic
carbene
(NHC)
salts,
copper(
i
)
chloride
alkali
metal
bases
including
alkoxides,
amides,
organolithium
produces
to
12
NHC-copper
complexes
in
moderate
good
yields.
Green Chemistry,
Год журнала:
2024,
Номер
26(10), С. 5890 - 5899
Опубликована: Янв. 1, 2024
A
novel
approach
utilizing
the
polymer-assisted
grinding
(POLAG)
technique
to
facilitate
regioselective
oxidative
Heck
coupling
of
aryl
boronic
acids
with
electronically
unbiased
olefins
under
solvent-free
conditions
was
presented.
