ACS Sustainable Chemistry & Engineering,
Год журнала:
2024,
Номер
12(12), С. 5046 - 5051
Опубликована: Март 14, 2024
A
sustainable
method
for
the
construction
of
valuable
β-keto
sulfones
lies
in
reaction
between
vinyl
azides
and
alkyl
sulfonyl
radical
generated
from
low-cost
comparatively
steady
bulk
chemical
dimethyl
sulfoxide
(DMSO)
that
has
been
developed.
This
strategy
features
mild
economical
conditions
using
inexpensive
NiCl2
as
catalyst
H2O2
green
oxidant.
The
conversion
occurs
through
a
sequence
ordered
processes
consisting
addition,
denitrogen,
hydrogen
abstraction,
hydrolysis.
Mechanistic
studies
indicate
sulfinic
acid
produced
DMSO
plays
an
essential
role
reduction
Ni(III).
sensitivity
assessment
gram-scale
experiments
proceed
smoothly
to
demonstrate
robustness
practicality
this
protocol.
Chemistry - A European Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 14, 2024
Photosynthesis,
converting
sustainable
solar
energy
into
chemical
energy,
has
emerged
as
a
promising
craft
to
achieve
diverse
organic
transformations
due
its
mild
reaction
conditions,
sustainability,
and
high
efficiency.
The
synthesis
of
sulfonated
compounds
drawn
significant
attention
in
the
pharmaceuticals,
agrochemicals,
materials
industries
unique
structure
electronic
properties
sulfonyl
groups.
Over
past
decades,
many
photocatalytic
sulfonylation
reactions
have
been
developed.
In
this
review,
recent
advances
photocatalyzed
reviewed
since
2020,
with
primary
focus
on
discussing
design
mechanism.
Asian Journal of Organic Chemistry,
Год журнала:
2023,
Номер
12(8)
Опубликована: Июнь 26, 2023
Abstract
The
upsurge
in
interest
the
development
of
methodologies
for
synthesis
sulfur‐containing
compounds
via
use
visible‐light
has
been
established
as
a
sustainable
tool
organic
chemistry.
Particularly,
mediated
C−S
bond
formation
gained
popularity
due
to
its
operational
simplicity,
minimized
by‐products,
easy
handling,
mild
reaction
conditions,
etc.
Photochemistry
not
only
provides
way
synthesize
complex
molecules
but
also
ability
overcome
many
challenges
which
are
difficult
attain
by
conventional
thermal
pathways.
Owing
biological
importance
compounds,
present
review
focused
on
under
metal‐free
conditions
visible‐light.
objective
current
is
bring
out
unearthing
collection
regarding
photoredox
catalysis.
For
better
understanding,
categorized
according
mode
reactions
viz
,
difunctionalization
alkenes
and
alkynes,
C−H
functionalization,
radical
cyclization.
All
each
sections
described
with
selected
examples
proper
explanation
proposed
mechanism.
Organic Letters,
Год журнала:
2023,
Номер
25(22), С. 4124 - 4129
Опубликована: Май 17, 2023
A
fully
heterogeneous
metallaphotocatalytic
C-C
cross-coupling
of
aryl/vinyl
halides
with
alkyl/allyltrifluoroborates
has
been
developed
by
employing
integrated
bipyridyl-Ni(II)-carbon
nitride
as
a
stable
and
recyclable
bifunctional
catalyst.
This
visible-light-mediated
protocol
allows
for
the
sustainable
synthesis
diverse
valuable
diarylmethanes
allylarenes
in
high
efficiency.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(20), С. 5190 - 5197
Опубликована: Янв. 1, 2023
An
efficient
and
rapid
iron-catalyzed
oxosulfonylation
of
alkynes
with
small-ring
compounds
Na
2
S
O
5
for
the
synthesis
β
-keto
sulfones
has
been
developed.
Angewandte Chemie International Edition,
Год журнала:
2023,
Номер
62(52)
Опубликована: Ноя. 10, 2023
Nitrogen-centered
radicals
(NCRs)
have
been
widely
recognized
as
versatile
synthetic
intermediates
for
the
construction
of
nitrogen
containing
molecules
high
value.
As
such,
there
has
a
long-standing
interest
in
field
organic
synthesis
to
develop
novel
nitrogen-based
and
explore
their
inherent
reactivity.
In
this
study,
we
present
generation
aromatic
N-heterocyclic
application
diverse
functionalization
unactivated
alkenes.
Bench-stable
pyridinium
salts
were
employed
crucial
NCR
precursors,
which
enabled
efficient
conversion
various
alkenes
into
medicinally
relevant
alkylated
amines.
This
approach
offers
an
unexplored
retrosynthetic
disconnection
related
that
commonly
possess
therapeutic
Furthermore,
platform
can
be
extended
densely
functionalized
heterocyclic
amines
by
utilizing
disulfides
diethyl
bromomalonate
radical
quenchers.
Mechanistic
investigations
indicate
energy
transfer
(EnT)
pathway
involving
formation
transient
radical,
addition
alkenes,
subsequent
amination
product
through
either
hydrogen
atom
(HAT)
or
processes.
