Lab on a Chip, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Schematic of DNAzyme-assisted DNA data writing on digital microfluidics.
Язык: Английский
Advanced Materials, Год журнала: 2024, Номер unknown
Опубликована: Фев. 21, 2024
Miniaturized droplets, characterized by well-controlled microenvironments and capability for parallel processing, have significantly advanced the studies on enzymatic evolution, molecular diagnostics, single-cell analysis. However, manipulation of small-sized including moving, merging, trapping targeted droplets complex biochemical assays subsequent analysis, is not trivial remains technically demanding. Among various techniques, light-driven methods stand out as a promising candidate droplet in facile flexible manner, given features contactless interaction, high spatiotemporal resolution, biocompatibility. This review therefore compiles an in-depth discussion governing mechanisms underpinning manipulation. Besides, light-responsive materials, representing core light-matter interaction key character converting light into different forms energy, are particularly assessed this review. Recent advancements materials most notable applications comprehensively archived evaluated. Continuous innovations rational engineering expected to propel development manipulation, equip with enhanced functionality, broaden routine investigations.
Язык: Английский
Процитировано
24
Virology Journal, Год журнала: 2024, Номер 21(1)
Опубликована: Март 7, 2024
Abstract Human metapneumovirus (HMPV) is a newly identified pathogen causing acute respiratory tract infections in young infants worldwide. Since the initial document of HMPV infection China 2003, Chinese scientists have made lots efforts to prevent and control this disease, including developing diagnosis methods, vaccines antiviral agents against HMPV, as well conducting epidemiological investigations. However, effective or special are currently not approved, thus early methods knowing its characteristics will be beneficial for control. Here, we summarized current research focused on available detection which increase public awareness disease future.
Язык: Английский
Процитировано
19
Biosensors and Bioelectronics, Год журнала: 2023, Номер 242, С. 115723 - 115723
Опубликована: Окт. 1, 2023
Язык: Английский
Процитировано
37
Advanced Functional Materials, Год журнала: 2023, Номер 34(9)
Опубликована: Ноя. 27, 2023
Abstract Controlling surface wettability and directing the flow of working fluids have crucial implications in various natural engineering contexts. Understanding fundamental principles directional wetting is essential for effectively leveraging these phenomena to enhance performance systems, such as microfluidics or heat exchangers. This comprehensive review summarizes previous research, emphasizing recent advances by categorizing structures associated with surfaces. The efforts researchers who employed diverse strategies manipulate behavior liquids through both passive active control mechanisms are highlighted. Passive transport surfaces require no additional energy while enabling large‐scale continuous fluid control. Conversely, offer enhanced flexibility precise liquid movement. Furthermore, insights into studies that focused on practical applications provided current challenges need be addressed discussed. study serves a guide future research directions development offers valuable recommendations implementation.
Язык: Английский
Процитировано
26
Lab on a Chip, Год журнала: 2024, Номер 24(19), С. 4483 - 4513
Опубликована: Янв. 1, 2024
This review summarizes programmable microfluidics, an advanced method for precise fluid control in microfluidic technology through microchannel design or liquid properties, referring to microvalves, micropumps, digital multiplexers, micromixers, slip-, and block-based configurations. Different microvalve types, including electrokinetic, hydraulic/pneumatic, pinch, phase-change check valves, cater diverse experimental needs. Programmable such as passive active play a crucial role achieving automation. Due their small size high integration, microvalves micropumps are widely used medical devices biological analysis. In addition, this provides in-depth exploration of the applications multiplexed mixer-based microfluidics manipulation movement, mixing, splitting. These methodologies leverage physical properties liquids, capillary forces dielectric forces, achieve over dynamics. SlipChip technology, which branches into rotational translational SlipChip, controls sliding motion microchannel. On other hand, innovative designs systems pursue better modularity, reconfigurability ease assembly. assembly strategies, from one-dimensional blocks two-dimensional Lego®-style three-dimensional reconfigurable modules, aim enhance flexibility accessibility. technologies user-friendliness accessibility by offering integrated systems, making them potentially usable outside specialized technical labs. Microfluidic strategies channels flow hold promising biomedical research, chemical analysis drug screening, providing theoretical practical guidance broader utilization scientific research applications.
Язык: Английский
Процитировано
13
Analytical Methods, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
This review explores emerging CRISPR-microfluidic platforms enhancing precision, speed, and portability for point-of-care diagnostics. Innovations like SHINE, CARMEN, ITP, DNAiTECH, Dμchip, FAST, MAPnavi highlight their potential.
Язык: Английский
Процитировано
2
Microsystems & Nanoengineering, Год журнала: 2025, Номер 11(1)
Опубликована: Янв. 9, 2025
Abstract Cardiovascular diseases account for ~40% of global deaths annually. This situation has revealed the urgent need investigation and development corresponding drugs pathogenesis due to complexity research methods detection techniques. An in vitro cardiomyocyte model is commonly used cardiac drug screening disease modeling since it can respond microphysiological environmental variations through mechanoelectric feedback. Microfluidic platforms are capable accurate fluid control integration with analysis Therefore, various microfluidic (i.e., heart-on-a-chip) have been applied reconstruction physiological environment signals from cardiomyocytes. They demonstrated advantages mimicking cardiovascular structure function monitoring electromechanical signals. review presents a summary technologies monitor contractility electrophysiological cardiomyocytes within platforms. Then, applications common presented, followed by design strategies enhancing physiology studies. Finally, we discuss prospects tissue engineering sensing techniques
Язык: Английский
Процитировано
1
Lab on a Chip, Год журнала: 2024, Номер 24(4), С. 904 - 912
Опубликована: Янв. 1, 2024
The microfluidic technique encapsulates perfluorohexanone for rapid fire extinguishing. Microcapsules quench flames larger than their size, extendable to two-dimensional patches, preventing spread.
Язык: Английский
Процитировано
8
Microsystems & Nanoengineering, Год журнала: 2024, Номер 10(1)
Опубликована: Сен. 27, 2024
Язык: Английский
Процитировано
8
Lab on a Chip, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
The microfluidic-based technique that combines efficient isolation of EVs and multiple detection EV cargos like proteins, nucleic acids, glycans at bulk, single/single cell level to further demystify heterogeneity.
Язык: Английский
Процитировано
1