Foods,
Год журнала:
2024,
Номер
13(14), С. 2226 - 2226
Опубликована: Июль 16, 2024
Bioactive
compounds
have
drawn
much
attention
according
to
their
various
health
benefits.
However,
poor
dissolvability,
low
stability
and
limited
bioavailability
largely
narrow
applications.
Although
a
variety
of
nontoxic
ingredients
been
rapidly
developed
as
vehicles
deliver
bioactive
in
the
last
few
years,
most
them
are
non-bioactive.
Pentacyclic
triterpenoids,
owing
unique
self-assembly
co-assembly
behaviors
different
physiological
functions,
can
construct
carriers
due
higher
biodegradability,
biocompatibility
lower
toxicity.
In
this
paper,
basic
classification,
biological
activities
physicochemical
properties
pentacyclic
triterpenoids
were
summarized.
Additionally,
applications
self-assembled
co-assembled
delivery
systems
load
components
future
research
directions
discussed.
This
study
emphasizes
potential
systems,
offering
new
perspective
for
constructing
self-
or
co-assemblies
further
synergetic
Life,
Год журнала:
2023,
Номер
13(7), С. 1514 - 1514
Опубликована: Июль 5, 2023
Rheumatoid
arthritis
(RA)
is
a
chronic
autoimmune
inflammatory
disease
characterized
by
joint
inflammation,
swelling
and
pain.
Although
RA
mainly
affects
the
joints,
can
also
have
systemic
implications.
The
presence
of
autoantibodies,
such
as
anti-cyclic
citrullinated
peptide
antibodies
rheumatoid
factors,
hallmark
disease.
significant
cause
disability
worldwide
associated
with
advancing
age,
genetic
predisposition,
infectious
agents,
obesity
smoking,
among
other
risk
factors.
Currently,
treatment
depends
on
anti-inflammatory
disease-modifying
anti-rheumatic
drugs
intended
to
reduce
inflammation
pain,
preventing
or
slowing
down
damage
progression.
However,
these
are
severe
side
effects
upon
long-term
use,
including
immunosuppression
development
opportunistic
infections.
Natural
products,
namely
triterpenes
properties,
shown
relevant
anti-arthritic
activity
in
several
animal
models
without
undesirable
effects.
Therefore,
this
review
covers
recent
studies
(2017-2022)
safe
promising
drug
candidates
for
RA.
These
bioactive
compounds
were
able
produce
reduction
indices
immunological
markers.
Celastrol,
betulinic
acid,
nimbolide
some
ginsenosides
stand
out
most
treatment.
Trends in Plant Science,
Год журнала:
2024,
Номер
29(5), С. 510 - 513
Опубликована: Март 13, 2024
With
the
rapid
development
of
molecular
sequencing
and
imaging
technology,
multi-omics
medicinal
plants
enters
single-cell
era.
We
discuss
spatial
applied
in
plants,
evaluate
special
products'
biosynthesis
pathways,
highlight
applications,
perspectives,
challenges
biomanufacturing
natural
products
(NPs).
Medicinal Plant Biology,
Год журнала:
2024,
Номер
3(1), С. 0 - 0
Опубликована: Янв. 1, 2024
The
Lonicera
genus
with
medicinal
and
edible
characteristics
is
a
rich
source
of
bioactive
compounds
that
together
account
for
numerous
health
benefits.
Plants
within
this
have
been
used
traditionally
in
China
to
treat
heat-related
illnesses,
viral
respiratory
infections,
skin
diseases,
inflammation
thousands
years.
main
include
chlorogenic
acids,
flavonoids,
iridoids,
triterpene
saponins.
Aside
from
the
role
as
valuable
resource,
constituent
members
also
food
cosmetic
industries.
Due
huge
demand
plants
propensity
overexploitation
wild
resources
Lonicera,
there
need
meet
via
alternative
efficient
strategies
such
metabolic
engineering
green
production.
Here,
we
provide
comprehensive
review
relevant
scientific
literature
covering
structure,
pharmacology,
multi-omics
analyses,
phylogenetic
analysis,
biosynthesis,
constituents
genus.
Finally,
proffer
suggestions
on
prospects
fully
exploiting
utilizing
useful
plant
resources.
Foods,
Год журнала:
2024,
Номер
13(14), С. 2226 - 2226
Опубликована: Июль 16, 2024
Bioactive
compounds
have
drawn
much
attention
according
to
their
various
health
benefits.
However,
poor
dissolvability,
low
stability
and
limited
bioavailability
largely
narrow
applications.
Although
a
variety
of
nontoxic
ingredients
been
rapidly
developed
as
vehicles
deliver
bioactive
in
the
last
few
years,
most
them
are
non-bioactive.
Pentacyclic
triterpenoids,
owing
unique
self-assembly
co-assembly
behaviors
different
physiological
functions,
can
construct
carriers
due
higher
biodegradability,
biocompatibility
lower
toxicity.
In
this
paper,
basic
classification,
biological
activities
physicochemical
properties
pentacyclic
triterpenoids
were
summarized.
Additionally,
applications
self-assembled
co-assembled
delivery
systems
load
components
future
research
directions
discussed.
This
study
emphasizes
potential
systems,
offering
new
perspective
for
constructing
self-
or
co-assemblies
further
synergetic
