Precision Molecular Engineering of Compact Near-Infrared Fluorophores
Journal of the American Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 4, 2025
Organic
fluorophores
with
near-infrared
(NIR)
emission
and
reduced
molecular
size
are
crucial
for
advancing
bioimaging
biosensing
technologies.
Traditional
methods,
such
as
conjugation
expansion
heteroatom
engineering,
often
fail
to
reduce
fluorophore
without
sacrificing
NIR
properties.
Addressing
this
challenge,
our
study
utilized
quantum
chemical
calculations
structure-property
relationship
analysis
establish
an
iterative
design
approach
enable
precision
engineering
compact,
single-benzene-based
fluorophores.
These
newly
developed
exhibit
emissions
up
759
nm
maintain
weights
low
192
g/mol,
approximately
50%
of
that
Cy7.
Additionally,
they
display
unique
environmental
sensitivity─nonemissive
in
aqueous
solutions
but
highly
emissive
lipid
environments.
This
property
significantly
enhances
their
utility
wash-free
imaging
live
cells.
Our
findings
mark
a
substantial
breakthrough
paving
the
way
more
efficient
adaptable
methodologies.
Язык: Английский
Position-induced differential aggregation behavior with red-shifted emission: A case study of the promising copper ion sensor skeleton-based regio-isomers
Journal of Photochemistry and Photobiology A Chemistry,
Год журнала:
2024,
Номер
458, С. 115931 - 115931
Опубликована: Авг. 12, 2024
Язык: Английский
One-Pot Synthesis of Vinylogous Cyano Aminoaryls (VinCAs) as Benzenic Fluorophores: Tailoring Diverse Emission Colors for White Light Emitting Materials and Cell Imaging
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(13), С. 9303 - 9312
Опубликована: Май 16, 2024
Donor–acceptor-based
organic
small
molecules
with
an
electronic
push–pull
effect
can
demonstrate
intramolecular
charge
transfer
to
show
interesting
photoluminescence
properties.
This
is
essential
criterion
for
designing
fluorogenic
probes
cell
imaging
studies
and
the
development
of
light-emitting
diodes.
Now,
design
such
optical
materials
sometimes
it
necessary
tune
band
gap
by
controlling
energies
highest
occupied
molecular
orbital
lowest
unoccupied
orbital.
Typically,
gaps
could
be
modulated
installing
unsaturated
handles
between
electron-rich
donors
electron-deficient
acceptors.
However,
these
methods
are
often
synthetically
economically
challenging
due
involvement
expensive
catalysts
difficult
reaction
setups.
In
our
present
study,
we
a
straightforward,
cost-effective
method
obtaining
series
donor–acceptor-type
Vinylogous
Cyano
Aminoaryls
(VinCAs)
diverse
emission
colors.
Further
reveal
that
VinCAs
serve
as
effective
agents,
showcasing
potential
use
in
chemical
biology.
Additionally,
further
used
generate
white
light
(WLE),
showing
their
utility
advanced
lighting
technologies.
Язык: Английский
Storehouse of Peculiar Supramolecular Architecture: Probing the Charge-Transfer Phenomenon and Effect of Altering the pH in a Meta-Oriented Single Donor-Double Acceptor Fluorophore
The Journal of Physical Chemistry A,
Год журнала:
2024,
Номер
128(41), С. 8914 - 8924
Опубликована: Окт. 4, 2024
The
investigation
of
excited-state
intramolecular
charge
transfer
(ESICT)
has
been
a
fascinating
area
research.
Although
the
ESICT
events
have
studied
mostly
for
Язык: Английский
Synthesis and Derivatization of Diaminobenzene Fluorophores with Amine Protecting Groups
Synthesis,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 7, 2024
Abstract
Introducing
two
electron-donating
groups
and
electron-withdrawing
together
in
symmetrical
positions
on
the
benzene
ring
is
a
fundamental
way
to
synthesize
prepare
single-benzene-based
fluorophores
(SBBFs).
Their
photophysical
properties
are
adjusted
through
electronic
structural
of
functional
groups.
Reported
herein
functionalization
diaminobenzene
derivatives
with
various
amine
protecting
groups,
including
amides,
urea,
carbamates,
sulfonamides.
Both
absorption
emission
obtained
SBBF
molecules
were
carefully
investigated.
Sequential
unsymmetric
diamine
protections
also
explored
for
fine-tuning
molecular
properties.
Язык: Английский
Structural and electronic tuning of single-benzene fluorophores with simple methylations
Dyes and Pigments,
Год журнала:
2024,
Номер
unknown, С. 112523 - 112523
Опубликована: Окт. 1, 2024
Язык: Английский
Charge-Transfer Mediated J-aggregation in Red Emitting Ultra-Small-Single-Benzenic Meta-Fluorophore Crystal
Chemical Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 27, 2024
Red
emission
in
crystals
has
been
observed
with
an
ultra-small-single-benzenic
Язык: Английский