Targets,
Год журнала:
2024,
Номер
2(4), С. 372 - 384
Опубликована: Ноя. 19, 2024
Molecular
cages
have
promising
host–guest
properties
for
drug
delivery
applications.
Specifically,
guest⊂cage
complexes
can
be
used
the
on-command
release
of
encapsulated
guest
molecules
in
response
to
specific
stimuli.
This
research
explores
both
dynamic
and
constrictive
binding
systems
encapsulation
biological
environments.
In
systems,
rapidly
passes
in-and-out
through
portals
cage,
enabling
vitro
but
facing
limitations
vivo
due
dilution
effects
that
result
release.
These
challenges
are
addressed
by
where
is
trapped
a
“gate-closed”
state
within
cage.
these
triggered
“gate
opening”
event,
which
lowers
guest–out
energy
barrier.
A
full
achieved
when
gate
opening
reduces
cage–guest
affinity,
making
more
effective
controlled
delivery.
As
result,
this
study
shows
suitable
contexts.
Chemical Science,
Год журнала:
2024,
Номер
15(26), С. 10010 - 10017
Опубликована: Янв. 1, 2024
A
comparative
study
between
a
metallo-organic
cage
and
fully
organic
analogous
system
shows
that
the
molecular
has
suitable
stability
doxorubicin
affinity
for
in
vitro
anticancer
drug
delivery.
Frontiers in Chemistry,
Год журнала:
2024,
Номер
12
Опубликована: Фев. 15, 2024
Extended
organic
polymers
such
as
amorphous
Covalent
Organic
Polymers
(COPs)
and
crystalline
Frameworks
(COFs)
are
emerging
functional
polymeric
materials
that
have
recently
been
shown
promises
luminescent
for
chemosensing
applications.
A
wide
variety
of
luminescence
COPs
COFs
synthesized
successfully
used
fluorescence-sensing
hazardous
environmental
pollutants
toxic
contaminants.
This
review
exemplifies
various
COFs-based
fluorescence
sensors
selective
sensing
Fe(III)
ions.
The
sorted
according
to
their
structural
features
each
section
provides
a
detailed
discussion
on
the
synthesis
ability
different
towards
Also,
this
highlights
limitations
existing
polymer-based
chemosensors
future
perspectives
translating
practical
detection
Chemical Communications,
Год журнала:
2024,
Номер
60(77), С. 10768 - 10771
Опубликована: Янв. 1, 2024
Dihydroxy-based
polar
organic
cages
(DIHO-cages)
are
reported
to
selectively
separate
toluene
with
99.5%
purity
from
an
equimolar
toluene/pyridine
mixture,
resulting
in
subsequent
superior
purification
of
pyridine.
The
efficient
separation
and
purification,
enhanced
by
strong
multiple
host/guest
C-H⋯O
interactions
between
the
cage
toluene,
showcases
DIHO-cages
as
a
suitable
candidate
for
remarkable
such
azeotropes
on
industrial
scale.
Analysis & Sensing,
Год журнала:
2024,
Номер
unknown
Опубликована: Июнь 5, 2024
Abstract
Point‐of‐care
diagnostics
relies
on
optical
and
electrochemical
sensors
to
develop
devices
that
are
both
compact
cost‐effective.
Therefore,
the
search
for
new
design
principles
chemosensors
enable
multiple
signal
outputs
is
a
particularly
interesting
concept.
In
this
work,
we
present
an
unimolecular
chemosensor
based
cucurbit[7]uril
combines
two
readouts
‐
namely
fluorescent
signals
in
single
design.
This
achieved
by
utilizing
tunable
fluorescence
properties
of
reporter
molecule,
which
depend
whether
or
not
it
engulfed
cavity
absence
presence
analyte.
By
setting
up
assay
using
dual
readout
chemosensor,
illicit
drug
formulations
containing
pancuronium
bromide
nicotine
can
be
detected
at
low
micromolar
concentrations
(0–100
μM).
compatible
with
standard
plate
readers
devices,
including
commercially
available
screen‐printed
electrodes.
Overall,
presented
study
represents
significant
advance
development
chemosensors,
characterized
multimodal
detection
capabilities.
It
uniquely
traditional
methods
molecular
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
The
bisureas
demonstrated
interesting
differences
in
complexation:
the
meta
,
and
para
isomers
preferred
2
:
1
complexes,
while
analogous
isomer
formed
a
complex.
RSC Sustainability,
Год журнала:
2024,
Номер
2(11), С. 3345 - 3352
Опубликована: Янв. 1, 2024
β-Keto-enamine
POPs,
synthesized
in
water
at
relatively
low
temperatures,
without
catalysts,
and
using
common
glassware,
exhibit
a
competitive
adsorption
capacity
high
selectivity
for
CO
2
over
N
298
K
(1
bar).
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(22), С. 11861 - 11861
Опубликована: Ноя. 5, 2024
Molecular
cages
are
preorganized
molecules
with
a
central
cavity,
typically
formed
through
the
reaction
of
their
building
blocks
chemical
bonds.
This
requires,
in
most
cases,
forming
and
breaking
reversible
bonds
during
cage
formation
pathway
for
error
correction
to
drive
product.
In
this
work,
we
focus
on
both
Pd-ligand
hydrazone
implemented
structure
Pd
