Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Ноя. 15, 2024
Abstract
A
Viral
Infection
Risk
Indoor
Simulator
(VIRIS)
has
been
developed
to
quickly
assess
and
compare
mitigations
for
airborne
disease
spread.
This
agent-based
simulator
combines
people
movement
in
an
indoor
space,
viral
transmission
modelling
detailed
architectural
design,
it
is
powered
by
topologicpy,
open-source
Python
library.
VIRIS
generates
very
fast
predictions
of
the
concentration
spatiotemporal
infection
risk
individuals
as
they
move
through
a
given
space.
The
validated
with
data
from
courtroom
superspreader
event.
sensitivity
study
unknown
parameter
values
also
performed.
We
several
non-pharmaceutical
interventions
(NPIs)
issued
UK
government
guidance,
two
settings:
care
home
supermarket.
Additionally,
we
have
user-friendly
web
app
that
allows
quick
exploration
diverse
scenarios
interest
visualisation,
allowing
policymakers,
architects
space
managers
easily
design
or
Abstract
Bacterial
infection
is
a
crucial
factor
resulting
in
public
health
issues
worldwide,
often
triggering
epidemics
and
even
fatalities.
The
accurate,
rapid,
convenient
detection
of
viable
bacteria
an
effective
method
for
reducing
infections
illness
outbreaks.
Here,
unsupervised
learning–assisted
surface
acoustic
wave–interdigital
transducer‐driven
nano‐lens
holography
biosensing
platform
developed
the
ultrasensitive
amplification‐free
bacteria.
monitoring
device
integrated
with
effect
can
achieve
holographic
imaging
polystyrene
microsphere
probes
ultra‐wide
field
view
(∽28.28
mm
2
),
sensitivity
limit
as
low
99
nm.
A
lightweight
learning
hologram
processing
algorithm
considerably
reduces
training
time
computing
hardware
requirements,
without
requiring
datasets
manual
labels.
By
combining
phage–mediated
bacterial
DNA
extraction
enhanced
CRISPR–Cas12a
systems,
this
strategy
successfully
achieves
Salmonella
various
real
samples,
demonstrating
accuracy
validated
qPCR
benchmark
method.
This
approach
has
cost
(∽$500)
rapid
(∽1
h)
highly
sensitive
(∽38
CFU
mL
−1
allowing
emerging
powerful
tool
food
safety
inspection
clinical
diagnosis.
Scientific Reports,
Год журнала:
2023,
Номер
13(1)
Опубликована: Дек. 21, 2023
A
proof
of
principle
biosensor
for
the
Brucella
abortus
recognition
onsite
is
presented.
The
system
based
on
a
plasmonic
optical
fiber
probe
functionalized
with
an
oriented
antibody
layer
immobilized
short
polyethyleneglycol
(PEG)
interface
through
carbodiimide
chemistry
and
protein
G
as
intermediate
layer.
inserted
in
holder
built
3D
printing
technology,
obtaining
custom
useful
housing
sample
to
be
measured
equipment.
removable
sensor
chip
low-cost
Surface
Plasmon
Resonance
(SPR)
platform
D-shaped
plastic
fibers
(POFs),
built-in
printed
connectors,
used
here
first
time
detect
bacteria
via
bio-receptor
specific
its
membrane
protein.
performances
are
tested
by
using
two
different
SPR-POF
probes
combined
same
best
configuration
has
presented
sensitivity
at
low
concentrations
one
order
magnitude
greater
than
other.
limit
detection
(LoD)
2.8
bacteria/mL
achieved
well
competitive
other
systems
but
without
need
amplification
or
special
treatments.
Specificity
been
Salmonella
bacteria,
reproducibility,
regenerability
stability
moreover
evaluated.
These
experimental
results
pave
way
building
efficient
few
minutes.
Moreover,
proposed
POF-based
SPR
device,
respect
already
available
technologies,
could
Point-of-care-test
(POCT),
simple
use,
small-size
portable,
low-cost,
don't
necessary
microfluidic
system,
can
connected
Internet
(IoT).
Aerobiology,
Год журнала:
2024,
Номер
2(4), С. 72 - 84
Опубликована: Сен. 24, 2024
Bioaerosols
constitute
a
crucial
component
of
atmospheric
particulate
matter,
encompassing
physical
and
chemical
aerosol
properties
along
with
biological
characteristics.
They
can
influence
global
ecosystems,
climate
change
dynamics,
air
quality.
Notably,
bioaerosols
serve
as
significant
pathway
for
transmitting
respiratory
infectious
diseases,
garnering
widespread
attention
worldwide
following
major
pandemics
such
COVID-19.
Thanks
to
the
development
high-throughput
sequencing
technologies,
studies
on
have
flourished
in
recent
years.
Understanding
interconnectedness
sources,
spatial
temporal
distributions,
influencing
factors,
health
risks
associated
is
imperative
devising
pollution
mitigation
strategies
preventing
spread
related
epidemics.
This
review
provides
an
overview
bioaerosol
sources
while
elucidating
distribution
patterns
within
their
community
structure
across
various
source
types.
Lastly,
this
offers
insights
into
future
advancements
field
corresponding
recommendations.
Epidemiology and Infectious Diseases,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 3, 2025
Background.
The
organization
and
implementation
of
disinfection
measures
is
one
the
main
infectious
diseases
non-specific
prevention.
Recently,
aerosol
disinfection,
which
a
convenient
effective
method,
has
become
more
utilized.
Materials
methods.
For
our
literature
search,
we
used
following
keywords:
"aerosol
disinfection",
"prevention",
"anti-epidemic
measures",
"ventilation".
We
searched
for
articles
in
Russian
English
languages
scientific
electronic
libraries
eLibrary,
Google
Scholar,
PubMed
(Medline,
database
National
Center
Biotechnology
Information
USA
(NCBI).
Our
search
was
limited
to
period
from
1940
2024.
As
result,
found
1,751
publications,
55
met
specified
criteria.
Results.
history
dates
back
end
XVIII
century
since
been
widely
many
countries
various
spheres
life.
This
method
becoming
increasingly
demand
as
an
way
prevent
diseases.
In
modern
world,
technologies
have
integral
part
daily
lives.
Nevertheless,
there
are
unresolved
issues
related
effectiveness
aerosols,
optimization
equipment
development
standards
ensure
high-quality
disinfection.
Conclusion.
Disinfection
using
aerosols
important
tool
system
aimed
at
preventing
fighting
epidemics.
It
significantly
reduces
risk
outbreaks
that
can
be
transmitted
different
ways.
Keywords:
prevention,
anti-epidemic
measures.
