Optimized ultrasonic-NaDES extraction of anthocyanins, polyphenolics, and organic acids from chokeberry fruit with blueness and antimicrobial evaluation
Microchemical Journal,
Год журнала:
2025,
Номер
unknown, С. 113061 - 113061
Опубликована: Фев. 1, 2025
Язык: Английский
Unlocking sustainable extraction of natural antioxidants: Green solvents, smart technologies, scalability and future directions
Separation Science and Technology,
Год журнала:
2025,
Номер
unknown, С. 1 - 27
Опубликована: Янв. 15, 2025
The
sustainable
extraction
of
natural
antioxidants
from
plants
has
gained
significant
attention
as
a
viable
alternative
to
synthetic
options
in
the
food
industry.
However,
traditional
processes
often
rely
on
hazardous
solvents,
raising
concerns
about
toxicity
and
environmental
impact.
This
review
highlights
transformative
potential
green
solvents
innovative
technologies
advancing
practices
aligned
with
Sustainable
Development
Goals.
Key
findings
include
effectiveness
intensification
techniques,
such
ultrasound-assisted
microwave-assisted
extractions,
enhancing
efficiency
reducing
resource
use.
also
explores
solutions
critical
challenges
like
solvent
recovery
recycling,
promising
approaches
biphasic
systems
situ
methods
demonstrating
industrial
feasibility.
Notably,
this
work
bridges
gap
between
laboratory-scale
research
large-scale
production
by
emphasizing
strategies
improve
process
scalability.
By
synthesizing
current
trends
identifying
future
directions,
offers
unique
insights
into
commercially
for
antioxidant
extraction,
positioning
essential
tools
more
Язык: Английский
Green Extraction of Bioactives from Curcuma longa Using Natural Deep Eutectic Solvents: Unlocking Antioxidative, Antimicrobial, Antidiabetic, and Skin Depigmentation Potentials
Plants,
Год журнала:
2025,
Номер
14(2), С. 163 - 163
Опубликована: Янв. 8, 2025
This
study
evaluates
the
efficiency
of
20
Natural
Deep
Eutectic
Solvents
(NADES)
formulations
for
extracting
curcuminoids
and
other
bioactive
compounds
from
turmeric
emphasize
their
ability
to
preserve
enhance
antioxidant,
antimicrobial,
antidiabetic,
skin
depigmentation
effects.
The
NADES
formulations,
prepared
using
choline
chloride
(ChCl)
combined
with
sugars,
carboxylic
acids,
glycerol,
amino
urea,
polyols,
betaine,
were
assessed
extraction
based
on
total
phenolic
content
curcumin
concentration.
Fourier
transform
infrared
spectroscopy
was
employed
characterize
synthesized
confirm
chemical
composition.
Bioactivity
evaluations
included
antioxidant
assays
(ABTS
DPPH),
antidiabetic
tests
(α-amylase
inhibition),
antimicrobial
assays,
(tyrosinase
inhibition).
results
demonstrated
that
significantly
enhanced
properties
extracts
compared
water
as
a
conventional
green
solvent.
18
(ChCl/1,2-propanediol/water
1:1:1)
19
(glycerol/betaine/water
1:1:3)
exhibited
highest
yields,
concentrations
30.73
±
1.96
mg/g
31.70
2.02
mg/g,
respectively,
outperforming
(26.91
1.72
mg/g),
while
17
0.5:3:0.5:5)
(glycerol/lysine/water
most
potent
activity.
Furthermore,
14
(ChCl/lactic
acid/water
1:2:5)
strongest
tyrosinase
inhibition
(98.7%),
supporting
its
potential
skin-brightening
applications,
including
notable
α-amylase
exceeding
90%.
aligns
principles
chemistry,
are
effective
sustainable
solvents
natural
product
extraction.
presenting
benefits
improved
bioactivities
position
promising
eco-friendly
approach
developing
efficient
compound
methodologies.
Язык: Английский
Polyphenols Extraction from Different Grape Pomaces Using Natural Deep Eutectic Solvents
Separations,
Год журнала:
2024,
Номер
11(8), С. 241 - 241
Опубликована: Авг. 8, 2024
Exploiting
by-products
from
the
oenological
industry
to
extract
antioxidant
chemicals
is
a
shared
goal
that
combines
need
reduce
wine
sector’s
environmental
impact
with
improve
availability
of
these
biomolecules,
according
circular
economy
approach.
Natural
deep
eutectic
solvents
(NaDES)
have
recently
captured
researchers’
interest
as
safer
and
more
environmentally
friendly
alternative
traditional
due
their
effectiveness,
low
toxicity,
stability.
In
this
work,
we
set
out
investigate
several
NaDES
for
extraction
phenolic
local
monovarietal
grape
pomace
resulting
different
vinification
procedures
(including
both
red
rosé
Negroamaro
Primitivo
grapes;
Susumaniello
grapes
white
Chardonnay,
Fiano
Malvasia
bianca
grapes),
additional
generalizing
use
organisms
selected
wide
plant
biodiversity.
Three
binary
choline
chloride-based
(DES-Lac,
DES-Tar,
DES-Gly,
lactic
acid,
tartaric
glycerol
hydrogen
bond
donors,
respectively)
were
compared
ethanol
conventional
solvent,
extracts
evaluated
using
HPLC/MS
colorimetric
techniques.
The
results
revealed
each
produces
substantially
higher
total
yield
than
(up
127.8
mg/g
DW
pomace).
DES-Lac
DES-Tar
effective
anthocyanins
extraction;
most
abundant
compound
was
malvidin
3-O-glucoside
(highest
pomace:
29.4
DW).
Regarding
compounds,
DES-Gly
producing
comparable
ethanol.
Unexpectedly,
Chardonnay
has
greatest
content
astilbin.
cases,
obtained
by
provided
maximum
yield.
As
result,
emerged
viable
organic
solvent
techniques,
allowing
(or
equal)
yields
while
significantly
lowering
costs,
hazards,
impact.
Язык: Английский
Integration of HPTLC with ATR-FTIR, HRMS and bioquantification for evaluation of antibacterial and antioxidant compounds in marine sponges
Journal of Chromatography A,
Год журнала:
2025,
Номер
unknown, С. 465967 - 465967
Опубликована: Апрель 1, 2025
Язык: Английский
Bibliometric insights into the application of natural deep eutectic solvents in extracting bioactive compounds from fruit wastes
International Journal of Environmental Science and Technology,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 1, 2024
Язык: Английский
In Silico Analysis of the Molecular Interaction between Anthocyanase, Peroxidase and Polyphenol Oxidase with Anthocyanins Found in Cranberries
Victoria Araya,
Marcell Gatica,
Elena Uribe
и другие.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(19), С. 10437 - 10437
Опубликована: Сен. 27, 2024
Anthocyanins
are
bioactive
compounds
responsible
for
various
physiological
processes
in
plants
and
provide
characteristic
colors
to
fruits
flowers.
Their
biosynthetic
pathway
is
well
understood;
however,
the
enzymatic
degradation
mechanism
less
explored.
Anthocyanase
(β-glucosidase
(BGL)),
peroxidase
(POD),
polyphenol
oxidase
(PPO)
enzymes
involved
degrading
anthocyanins
such
as
petunias,
eggplants,
Sicilian
oranges.
The
aim
of
this
work
was
investigate
physicochemical
interactions
between
these
identified
(via
UPLC-MS/MS)
cranberry
(Vaccinium
macrocarpon)
through
molecular
docking
identify
residues
likely
anthocyanin
degradation.
Three-dimensional
models
were
constructed
using
AlphaFold2
server
based
on
consensus
sequences
specific
each
enzyme.
with
highest
confidence
scores
(pLDDT)
selected,
BGL,
POD,
PPO
achieving
87.6,
94.8,
84.1,
respectively.
These
then
refined
dynamics
100
ns.
Additionally,
UPLC-MS/MS
analysis
flavonoids
cranberries,
including
cyanidin,
delphinidin,
procyanidin
B2
B4,
petunidin,
pelargonidin,
peonidin,
malvidin,
providing
important
experimental
data
support
study.
Molecular
simulations
revealed
most
stable
anthocyanase
cyanidin
3-arabinoside
3-glucoside,
a
favorable
ΔG
interaction
−9.3
−9.2
kcal/mol.
This
study
contributes
proposing
seeking
inhibitors
prevent
fruit
discoloration.
Язык: Английский
Natural deep eutectic solvents for anthocyanin extraction from agricultural sources: Process parameters, economic and environmental analysis, and industrial challenges
Comprehensive Reviews in Food Science and Food Safety,
Год журнала:
2024,
Номер
23(6)
Опубликована: Ноя. 1, 2024
Abstract
Anthocyanins
are
natural
pigments,
known
for
their
antioxidant,
anti‐inflammatory
properties,
and
health
benefits.
One
method
to
extract
anthocyanins
uses
deep
eutectic
solvents
(NADES).
NADES
mixtures
of
two
or
more
compounds
that
result
in
a
liquid
with
lower
melting
point
than
any
its
individual
components.
nontoxic,
biodegradable
can
be
obtained
from
renewable
sources,
making
them
an
attractive
alternative
traditional
solvents;
therefore,
they
as
the
“21st
century
solvents.”
This
review
provides
comprehensive
critical
assessment
use
sustainable
solvent
system
extraction.
It
also
discusses
main
properties
anthocyanins,
NADES,
process
parameters,
economic
environmental
analysis
efficiently
anthocyanins.
Current
state
knowledge
focusing
on
applicability
within
industrial
context
was
evaluated
identified
gaps
knowledge,
highlighting
advantages
challenges
provide
recommendations
future
research.
Язык: Английский