Electrochemical Post-Ugi Cyclization for the Synthesis of Highly Functionalized Spirolactams

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(19), С. 13977 - 13994

Опубликована: Сен. 11, 2023

The combination of the Ugi reaction and electro-organic synthesis can aid in creation novel heterocycles that have not been previously explored. In this study, a new strategy utilizing bis-amides from has developed, which produce C–S, C–Se, C–C═O functionalized five-membered spirolactams mediated by electricity under catalyst- metal-free conditions. Notably, approach be applied using microelectro-flow reactor (μ-EFR) for gram-scale synthesis. described synthesize complex azaspiro-fused tricyclic scaffolds with high diastereo- regioselectivity, highlighting its versatility potential.

Язык: Английский

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Fe₃O₄@ABA-aniline-CuI nanocomposite as a highly efficient and reusable nanocatalyst for the synthesis of benzothiazole-sulfide aryls and heteroaryls

RSC Advances, Год журнала: 2023, Номер 13(29), С. 20351 - 20364

Опубликована: Янв. 1, 2023

Studying diaryl sulfides and benzothiazoles is important in organic synthesis because numerous natural medicinal products contain these scaffolds. Over the past few years, research on of compounds containing benzothiazole-sulfide aryls, as biological molecules, has received significant attention. Multicomponent reactions are most popular strategy for performing difficult complexed molecules such aryls. In this work, CuI was successfully immobilized surface magnetic Fe3O4 nanoparticles modified with aniline 4-aminobenzoic acid [Fe3O4@ABA-Aniline-CuI nanocomposite] its catalytic activity investigated preparation a broad range aryls heteroaryls through one-pot three-component 2-iodoaniline carbon disulfide aryl or heteroaryl iodides presence KOAc base PEG-400 solvent. TEM SEM images revealed that shape Fe3O4@ABA-Aniline-CuI particles spherical size approximately between 12-25 nanometers.

Язык: Английский

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A green and sustainable selective oxidation of aromatic sulfides to sulfoxides derivatives via graphite electro-catalysed reaction with sodium bromide

Journal of Molecular Structure, Год журнала: 2023, Номер 1293, С. 136271 - 136271

Опубликована: Июль 21, 2023

Язык: Английский

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Utilizing density functional theory (DFT) approach for predicting the optoelectronic, structural, and magnetic properties of the spin-polarized scintillating bromo-elpasolite Cs2LiCeBr6

Optical and Quantum Electronics, Год журнала: 2023, Номер 55(10)

Опубликована: Июль 23, 2023

Язык: Английский

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Selective Electrochemical Halogenation of Functionalized Quinolone

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(18), С. 12958 - 12970

Опубликована: Авг. 24, 2023

This work describes an effective C3–H halogenation of quinoline-4(1H)-ones under electrochemical conditions, in which potassium halides serve as both halogenating agents and electrolytes. The protocol provides expedient access to different halogenated with unique regioselectivity, broad substrate scope, gram-scale synthesis employing convenient, environmentally friendly electrolysis, undivided cell. Mechanism studies have shown that halogen radicals can promote the activation N–H bonds quinolones.

Язык: Английский

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Fabrication of Fe₃O₄-Bis(Py-Imine)-PdCl₂ Nanocomposite as a Highly Active Nanomagnetic Catalyst for Carbonylative Suzuki Reactions of Phenylboronic Acid with Aryl Iodides and Mo(CO)₆

Polycyclic aromatic compounds, Год журнала: 2023, Номер unknown, С. 1 - 17

Опубликована: Июль 20, 2023

In the research work, a novel and recoverable nanomagnetic pallidum catalyst [Fe3O4-Bis(Py-Imine)-PdCl2 ] based on immobilization of Pd surface magnetic Fe3O4 nanoparticles modified with picolylamine as ligand was designed fabricated. The structure as-fabricated Fe3O4-Bis(Py-Imine)-PdCl2 nanocatalyst characterized by FT-IR spectroscopy, SEM, TEM, EDX, ICP-OES, TGA, VSM, XRD EDX mapping techniques. nanocomposite demonstrated high activity in preparation diaryl ketones through one-pot three-component Suzuki reactions phenylboronic acids aryl iodides Mo(CO)6. recycling examined coupling acid 4-methyl iodobenzene Mo(CO)6; results revealed that this could be reused for more than 6 consecutive runs without loss activity. This method offers several remarkable features, such yield products, simplicity separation products from catalysts, performing green solvent mild conditions, ability to recycle reusing significant reduction its catalytic

Язык: Английский

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Recent advances in metal-organic frameworks synthesis and characterization with a focus on electrochemical determination of biological and food compounds, and investigation of their antibacterial performance

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION), Год журнала: 2023, Номер 51(8), С. 100286 - 100286

Опубликована: Май 27, 2023

Metal-organic frameworks (MOFs) are hybrid materials composed of both organic and inorganic elements. MOF materials, because their unique structures properties, such as controllable pore size, large surface area, excellent catalytic activity, high density active sites, applied in electrochemical sensors systems for the sensitive, quick, low-cost detection multiple analytes. MOFs, with specific shape, adjustable volume, will provide strong interaction compounds via abundant functional groups, leading to increased selectivity determination a wide range compounds. In this review, structure, synthesis methods, characterization, applications MOFs recent years sensing material fabricating detecting drugs, pesticides, heavy metals, food additives, other contaminants summarized, compared, discussed. Also, were used numerous antibacterial application areas due long-term release capability, stretch ability when integrated and/or substances (including nanostructures, phytochemicals, antibiotics, polymers). This review also provides comprehensive overview uses one's composite focus on different kinds nanocomposite influence various uses.

Язык: Английский

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Electrochemical and photocatalytic properties of ZnO nanostructures deposited on nanoporous anodized aluminum oxide membrane and its application for degradation of reactive blue 19 in textile wastewater

International Journal of Electrochemical Science, Год журнала: 2023, Номер 18(9), С. 100272 - 100272

Опубликована: Июль 1, 2023

The current study's objective was to develop a ZnO photocatalyst for the treatment of reactive blue 19 (RB19) from textile wastewater by depositing nanostructures over nanoporous anodized aluminum oxide (ZnO-AAO). ZnO-AAO membrane created using atomic layer deposition (ALD) technique. SEM, XRD, and EDS morphological structural characterizations demonstrated that were successfully deposited on AAO membrane. Studying optical properties revealed band gap energies ZnO, AAO, membranes found be 3.19, 2.85, 2.92 eV, respectively. This resulted in an improvement separation efficiency photo-excited electrons holes as well increase photocatalytic activity sample visible light region. electrochemical parameters had lowest charge transfer resistance, which indicates photoinduced contacts effectively have slower recombination rates. According research performance, photocatalysts required 70 90 minutes exposure completely decolorize RB19, decolorization RB19 actual showed dye could removed means when present.

Язык: Английский

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Electrochemical selenylative ipso-Annulation of N-benzylacrylamides to seleno-azaspiro[4.5]decadienones

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(30), С. 6141 - 6148

Опубликована: Янв. 1, 2024

Construction of seleno azaspiro[4.5]decadienones using an electrochemical approach is achieved via domino selenylation/ ipso -annulation.

Язык: Английский

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NiO Nanoparticle-decorated graphene oxide nanosheets modified glassy carbon electrode for sensitive electrochemical detection of pethidine

International Journal of Electrochemical Science, Год журнала: 2023, Номер 18(9), С. 100221 - 100221

Опубликована: Июнь 5, 2023

Pethidine (PTD), a synthetic opioid prescribed frequently as painkiller, was included in the WADA list of prohibited substances sports. The purpose this study is to investigate electrochemical determination PTD using modified glassy carbon electrode decorated with NiO nanoparticles and graphene oxide nanosheets (NiO-GO/GCE). NiO-GO nanocomposite created straightforward chemical reduction technique. SEM, TEM, XRD analysis structure morphology pointed nanocomposite's effective production. Results showed that NiO-GO/GCE responded sensitive, focused, stable manner relatively low detection limit value (3.8 ng/mL) wide linear range (0–500 μg/mL) compared other sensors. on appropriateness validation for determining content clinical human fluid samples illustrated good recoveries between 90.00 % 99.66 relative standard deviation less than 5.41 %, which were acceptable corroborated results sensor urine from healthy athlete volunteers.

Язык: Английский

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