RSC Sustainability,
Год журнала:
2024,
Номер
2(8), С. 2169 - 2189
Опубликована: Янв. 1, 2024
This
review
describes
the
recent
advancements
in
visible
light-induced
bromine
radical
enhanced
hydrogen
atom
transfer
(HAT)
reactions
organic
synthesis.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(8), С. 5229 - 5238
Опубликована: Март 29, 2024
Mechanochemistry
refers
to
the
initiation
of
chemical
reactions
via
mechanical
forces
such
as
milling,
grinding,
or
shearing
achieve
transformations.
As
a
manifestation
mechanocatalysis,
herein,
an
oxidant-free
and
solvent-free
approach
for
synthesis
quinazolinones
(23
derivatives)
benzothiazoles
has
been
developed
through
stainless-steel-driven
decarboxylative
acyl
radical
generation
from
α-keto
acids.
A
library
2-arylquinazolinones
2-arylbenzothiazoles
prepared
in
moderate
good
yields
at
room
temperature.
Moreover,
control
experiments
XPS
studies
supported
reduction
(by
zerovalent
iron)
molecular
oxygen
abrasion
balls,
which
promoted
superoxide
anion
SET
process.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 10, 2025
A
palladium-catalyzed
decarboxylative
allylic
sulfonylation
reaction
of
vinyloxazolidine-2,4-diones
with
inexpensive
and
readily
available
sodium
sulfinates
as
reagents
has
been
developed.
Under
the
catalysis
Pd(PPh3)4,
a
wide
range
γ-sulfonyl-α,β-unsaturated
amides
can
be
synthesized
in
good
to
excellent
yields.
The
developed
protocol
is
characterized
by
exclusive
regioselectivity,
mild
conditions,
broad
substrate
scope,
functional
group
tolerance,
suitable
for
gram-scale
synthesis.
A
successful
methodology
for
the
copper-catalyzed
dehydrogenated
methylsulfonylation
of
alkenes
utilizing
CH3SSO3Na
in
conjunction
with
hypervalent
iodine
reagents
was
successfully
established.
This
method
offers
a
practical
avenue
to
obtain
allyl
methyl
sulfones
and
alkenyl
by
forming
C-S
bonds.
Using
C-H
bond
oxidation
sulfonylation
strategy
Bunte
salts,
we
synthesized
total
twenty
two
compounds,
including
four
examples
deuterium-substituted
molecules,
demonstrated
one
example
scale-up
reaction.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 10, 2025
An
environmentally
friendly
and
practical
method
for
the
synthesis
of
various
vinyl
sulfones
was
developed
through
direct
sulfonylation
alkenyl
sulfonium
salts
with
sulfinic
acids.
The
reaction
effectively
triggered
by
combined
actions
milling,
sunlight,
photocatalysts
under
solvent-free
conditions,
offering
advantages
such
as
a
short
time
(5-10
min),
room
temperature,
straightforward
workup
procedure.
Preliminary
mechanistic
studies
suggested
that
sulfonyl
radical
may
be
involved
in
this
mechanophotocatalytic
transformation
process.
ACS Sustainable Chemistry & Engineering,
Год журнала:
2024,
Номер
12(34), С. 12808 - 12818
Опубликована: Авг. 15, 2024
Herein,
a
mechanochemically
triggered
C–H
arylation
of
coumarins,
quinoline-N-oxides,
and
uracil
molecules
with
aryl
thianthrenium
salts
is
described.
Aryl
are
primarily
acknowledged
for
their
expedient
reusability
adherence
to
atom
economy
principles.
Mechanistic
studies
suggested
that
mechanical
stress
promoted
the
homolytic
scission
C–S
bond
salts,
forming
radical
intermediate.
Later,
intermediate
engaged
in
addition
reaction
above
heterocycles,
leading
desired
products
good
yields.
This
versatile
protocol
accommodates
wide
range
functional
groups
facilitates
synthesis
bioactive
compounds
drug
molecules.
Green Chemistry,
Год журнала:
2024,
Номер
26(19), С. 10265 - 10274
Опубликована: Янв. 1, 2024
We
herein
describe
a
versatile
electron–donor–acceptor
(EDA)
mediated
thioesterification
reaction
using
aryl
sulfonium
salt
(acceptor)
with
potassium
thioacid
salts
(donor)
under
visible
light
irradiation.
Esters
represent
a
vital
functional
group
in
organic
chemistry
and
are
prominently
featured
valuable
molecules.
Traditional
approaches
for
ester
synthesis
from
acids
typically
entail
the
use
of
strong
toxic
activating
agents.
Photoacid-catalyzed
has
recently
come
to
fore
several
important
transformations
accruing
benefits
acid-based
reactions
under
mild
conditions.
In
this
context,
green
sustainable
method
esterification
is
proposed
wherein,
Eosin
Y
introduced
as
multifunctional
photoacid
catalyst
that
can
be
activated
with
visible
light
catalyze
carboxylic
acids.
The
present
strategy
fairly
broad
applies
cinnamic
acids,
α-keto
phenyl
propiolic
scope
alkyl
alcohols
includes
examples
therefore
provides
various
building
blocks
pharmaceutical
interest.
Elaborated
mechanistic
studies
revealed
proton-coupled
electron
transfer
(PCET)
between
acid
might
facilitate
formation
transient
ketyl
radical.
This
radical
would
subsequently
undergo
coupling
alcohols,
yielding
esters
good
excellent
yields.
Catalysis Science & Technology,
Год журнала:
2024,
Номер
14(18), С. 5143 - 5160
Опубликована: Янв. 1, 2024
This
review
article
summarizes
the
visible
light
mediated
synthesis
of
allenes
from
substrates
like
1,3-enynes,
propargylic
carbonates,
homopropargylic
alcohols,
oxalates,
alkynyl
diazo
compounds,
and
terminal
aziridines.
