A concise total synthesis of monoterpenoid indole alkaloid (-)-voacafricine A
Chinese Chemical Letters,
Год журнала:
2025,
Номер
unknown, С. 110913 - 110913
Опубликована: Фев. 1, 2025
Язык: Английский
1-benzyl-6-nitro-4-phenyl-4-(methoxycarbonyl)-2(1H)-pyridinone, a novel pirfenidone derivative, alleviate hepatic fibrosis through T cells
Biomedicine & Pharmacotherapy,
Год журнала:
2025,
Номер
184, С. 117907 - 117907
Опубликована: Фев. 19, 2025
Язык: Английский
Photoinduced [3+2] Cycloaddition of Alkyl–Acceptor Diazoalkanes: Diversity-Oriented Synthesis of Pyrazolines Containing a Quaternary Center
Fengya He,
Ziyi Sun,
Yiwei Xu
и другие.
Organic Letters,
Год журнала:
2024,
Номер
26(19), С. 4031 - 4036
Опубликована: Янв. 26, 2024
We
present
a
new
[3+2]
cycloaddition
reaction
between
alkyl-acceptor
diazoalkanes
under
visible
light
irradiation.
By
employing
easily
accessible
alkyl-acceptor-type
or
their
precursor
hydrazones
as
both
1,3-dipoles
and
dipolarophiles,
diverse
range
of
pyrazoline
derivatives
featuring
quaternary
center
have
been
efficiently
synthesized
in
predictable
manner,
with
excellent
functional
group
tolerance
good
yields.
Furthermore,
scale-up
experiments
downstream
transformations
the
product
were
also
detailed.
Язык: Английский
The efficient synthesis of three-membered rings via photo- and electrochemical strategies
Chemical Science,
Год журнала:
2024,
Номер
15(34), С. 13576 - 13604
Опубликована: Янв. 1, 2024
Three-membered
rings,
such
as
epoxides,
aziridines,
oxaziridines,
cyclopropenes,
vinyloxaziridines,
and
azirines,
are
recognized
crucial
pharmacophores
building
blocks
in
organic
chemistry
drug
discovery.
Despite
the
significant
advances
synthesis
of
these
rings
through
photo/electrochemical
methods
over
past
decade,
there
has
currently
been
no
focused
discussion
updated
overviews
on
this
topic.
Therefore,
we
presented
review
article
efficient
three-membered
using
photo-
electrochemical
strategies,
covering
literature
since
2015.
In
study,
a
conceptual
overview
detailed
discussions
were
provided
to
illustrate
advancement
field.
Moreover,
brief
outlines
current
challenges
opportunities
synthesizing
strategies.
Язык: Английский