Silver‐catalyzed Cascade Bis‐heteroannulation Reaction of Enynones and o‐Hydroxyphenyl Enaminones: Access to Highly Functionalized 3‐Furylmethyl Chromones
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(10), С. 2363 - 2369
Опубликована: Март 16, 2024
Abstract
A
synthetic
protocol
was
developed
to
synthesize
highly
functionalized
3‐furylmethyl
chromones
from
enynones
and
o
‐hydroxyphenyl
enaminones
via
silver‐catalyzed
cascade
bis‐heteroannulation
reaction.
This
strategy
features
broad
substrate
scope
good
functional
group
tolerance.
Furthermore,
the
chromone
skeleton
shows
potential
application
value
through
further
gram‐scale
synthesis
derivatization.
Язык: Английский
Recent advances in hydrofunctionalisation of cyclopropenes via carbon–heteroatom bond formation
Organic Chemistry Frontiers,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
This
review
highlights
recent
advances
in
the
hydrofunctionalisation
of
cyclopropenes
through
formation
carbon–heteroatom
bonds
for
synthesis
polysubstituted
cyclopropanes.
Язык: Английский
Oxidative Free-Radical C(sp2)–H Bond Chlorination of Enaminones with LiCl: Access to Highly Functionalized α-Chlorinated Enaminones
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(12), С. 8521 - 8530
Опубликована: Июнь 3, 2024
An
oxidative
free-radical
C(sp2)–H
bond
chlorination
strategy
of
enaminones
has
been
developed
by
using
LiCl
as
a
chlorinating
reagent
and
K2S2O8
an
oxidant.
This
transformation
provides
new
straightforward
synthetic
methodology
to
afford
highly
functionalized
α-chlorinated
with
Z-configuration
in
good
excellent
yields.
Язык: Английский
Copper-Catalyzed Oxidative [3 + 2] Cycloaddition of Enamines and Pyridotriazoles toward Indolizines
Organic Letters,
Год журнала:
2024,
Номер
26(6), С. 1249 - 1254
Опубликована: Фев. 2, 2024
An
efficient
copper
catalytic
system
has
been
established
for
the
synthesis
of
highly
functional
indolizines
through
oxidative
[3
+
2]
cycloaddition
enamines
and
pyridotriazoles.
This
modular
platform
is
compatible
with
a
broad
range
groups,
including
natural
complex
skeletons,
allowing
late-stage
modifications.
It
features
step-economical,
regioselective,
easy-handling
procedure
applied
in
constructing
small
molecules
potent
activity
toward
inhibiting
VEGF–NRP1
interaction
one-pot
reaction
pyridotriazoles,
amines,
aldehydes.
Язык: Английский
Pd(II) Auxiliaries Assembling and Diverse Transformations via Inert C(sp3)–H Bond Activation
Organic Chemistry Frontiers,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
The
construction
of
new
C–C
bonds
via
inert
C(sp
3
)–H
bond
activation
has
garnered
significant
achievements
in
recent
decades,
particularly
with
palladacycles
serving
as
pivotal
intermediates.
Язык: Английский
Rh-Catalyzed Enantioselective Synthesis of Acyclic Quaternary Carbons via Carbene Insertion
ACS Catalysis,
Год журнала:
2025,
Номер
unknown, С. 5273 - 5282
Опубликована: Март 13, 2025
Язык: Английский
Cascade Annulation for Synthesizing Chromenopyrrolones from o-Hydroxyphenyl Enaminones and 2-Halo-N-alkyloxyacetamides
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 27, 2024
A
cascade
cyclization
reaction
comprising
two
halogenation
reactions
and
a
Michael
addition
was
developed
for
the
synthesis
of
chromeno[2,3-
Язык: Английский
NBS-Mediated C(sp2)-H Bond Chlorination of Enaminones: Using DCE as Chlorine Source
Menglin Peng,
Yunhua Xie,
Siyu Song
и другие.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(22), С. 12073 - 12073
Опубликована: Ноя. 10, 2024
Commercial
DCE
is
excavated
as
both
a
"Cl"
source
and
solvent
for
the
vinyl
C(sp
Язык: Английский