Visible photons as ideal reagents for the activation of coloured organic compounds
Chemical Society Reviews,
Год журнала:
2024,
Номер
53(10), С. 4926 - 4975
Опубликована: Янв. 1, 2024
In
search
for
the
perfect
wave(length).
This
review
is
dedicated
to
recent
efforts
in
development
of
visible
light
driven
photochemical
strategies
occurring
coloured
organic
compounds.
Язык: Английский
Sc-Catalyzed Asymmetric [2 + 2] Annulation of 2-Alkynylnaphthols with Dienes to Access Cyclobutene Frameworks
Organic Letters,
Год журнала:
2025,
Номер
27(4), С. 1006 - 1011
Опубликована: Янв. 16, 2025
Herein,
we
introduce
a
scandium-catalyzed
synthetic
strategy
that
provides
access
to
diverse
and
functionalized
array
of
cyclobutene
frameworks
adorned
with
quaternary
carbon
center.
This
approach
broadens
the
repertoire
2-alkynylnaphthols
alkenes,
offering
versatile
platform
for
construction
complex
molecular
architectures.
The
asymmetric
catalytic
[2
+
2]
cycloaddition
reaction
demonstrates
wide
substrate
scope
an
impressive
functional
group
tolerance,
yielding
products
high
efficiency,
up
97%
yield,
excellent
enantiomeric
excess
97%.
simplicity
scaling
this
process,
coupled
ease
converting
these
into
variety
substituted
products,
significantly
enhances
utility
method.
Язык: Английский
Metal-free assembly of diverse polysubstituted pyridines via an efficient cascade approach using tertiary enaminones and α,β-unsaturated sulfonylketimines
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(9), С. 2607 - 2612
Опубликована: Янв. 1, 2024
A
metal-free,
scalable,
and
cascade
protocol
for
assembling
diverse
polysubstituted
pyridines
from
tertiary
enaminones
α,β-unsaturated
sulfonylketimines
by
cleaving
C–N/N–S
bonds
is
reported.
Язык: Английский
Visible-light-mediated substituent-controlled regiodivergent (2 + 2)/(3 + 2) cycloadditions for the synthesis of aza-analogs of β-lactam and γ-fused lactam derivatives
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(13), С. 3576 - 3582
Опубликована: Янв. 1, 2024
Substituent-controlled
regiodivergent
synthesis
of
aza-analogs
β-lactam
and
γ-fused
lactam
derivatives
via
the
visible-light-induced
Wolff
rearrangement
α-diazoketones
azo
esters.
Язык: Английский
The Wolff Rearrangement
Elsevier eBooks,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Язык: Английский
Synthesis of α-Chiral Amides via Synergistic Visible-light-induced Wolff Rearrangement and Asymmetric NHC Catalysis
Jiaomei Wang,
Yangxu Chen,
Siyan Miao
и другие.
New Journal of Chemistry,
Год журнала:
2024,
Номер
48(35), С. 15287 - 15291
Опубликована: Янв. 1, 2024
Herein,
a
visible-light-induced
chiral
N-heterocyclic
carbene
(NHC)
catalyzed
asymmetric
amination
of
ketenes
has
been
developed.
This
strategy
provides
facile
synthetic
protocol
for
the
efficient
construction
α-chiral
amides.
Язык: Английский
Photochemically Induced Approaches to the Syntheses of β‐Lactams
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(22), С. 4548 - 4558
Опубликована: Окт. 8, 2024
Abstract
The
synthesis
of
β‐lactam
scaffolds
is
paramount
importance
due
to
their
extensive
applications
in
pharmaceuticals,
particularly
as
antibiotics.
Visible
light
photocatalysis
has
emerged
a
revolutionary
approach
this
domain,
providing
sustainable
and
efficient
pathway
for
construction.
In
review,
we
meticulously
discuss
the
recent
developments
photocatalysed
frameworks.
A
key
focus
Staudinger
reaction,
traditionally
cornerstone
synthesis,
its
adaptation
visible
photocatalysis.
We
explore
mechanistic
intricacies
reaction
under
photochemical
conditions,
along
with
other
pivotal
cyclization
strategies
enabled
by
light.
By
illuminating
novel
photocatalytic
routes
β‐lactams,
review
provides
thorough
understanding
state‐of‐the‐art
techniques
sets
stage
future
innovations
green
these
critical
compounds.
Язык: Английский
Two photons are better than one: continuous flow synthesis of ꞵ-lactones through a doubly photochemically-activated Paternò-Büchi reaction
Journal of Flow Chemistry,
Год журнала:
2023,
Номер
14(1), С. 149 - 159
Опубликована: Дек. 15, 2023
Abstract
In
this
paper
we
report
a
[2
+
2]
cycloaddition
reaction
between
ketenes
and
benzils,
characterized
by
an
unusual
double
photochemical
activation
triggered
visible
light.
Employment
of
flow
system
optimization
conditions
through
Design
Experiments
resulted
in
moderate
to
good
yields
the
corresponding
β-lactones.
A
thorough
computational
analysis
allowed
elucidate
mechanism
justify
observed
diastereoselectivity.
The
was
also
successfully
tested
with
mixed
showing
complete
regioselectivity.
Graphical
abstract
Язык: Английский