Facile synthesis of the unknown 6,7-dihydrofuro[3,4-c]pyridines and 3,4-diaryloylpyridines from N-propargyl β-enaminones
Organic & Biomolecular Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
A
simple
methodology
for
the
synthesis
of
bicyclic
6,7-dihydrofuro[3,4-
c
]pyridines
is
reported.
The
skeletal
diversity
synthesized
heterobicyclic
frame
may
present
new
nitrogen-
and
oxygen-based
hybrid
systems
medicinal
chemistry.
Язык: Английский
Mechanosynthesis of polysubstituted pyridines via FeBr3-catalyzed cascade reaction of arylidene isoxazolones with β‑carbonyl esters
Tetrahedron Letters,
Год журнала:
2025,
Номер
unknown, С. 155569 - 155569
Опубликована: Март 1, 2025
Язык: Английский
Iron(III)-Catalyzed Amine-Release Triple Condensation of Enaminones to C3-Alkenylated Dihydroquinolinones
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(15), С. 10538 - 10550
Опубликована: Июль 12, 2024
C3-functionalized
dihydroquinolinones
represent
a
class
of
important
biologically
active
compounds.
Although
methods
for
synthesizing
C2/4-functionalized
have
been
extensively
reported,
research
on
the
synthesis
dihydroquinolinone
is
extremely
rare.
Herein,
we
report
first
time
method
C3-alkenylated
via
iron(III)-catalyzed
amine-release
triple
condensation
enaminones.
These
reactions
exhibit
broad
substrate
scope
and
offer
operationally
simple,
low-cost
catalyzed
procedures
in
single
step.
Subsequent
intramolecular
intermolecular
additions
to
alkene
moiety
provide
diverse
derivatives.
Язык: Английский
Rhodium(III)-Catalyzed Sequential Cyclization of Enaminones with 1,3-Dienes via C–H Activation for the Synthesis of Fluorenones
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 19, 2024
An
efficient
method
for
construction
of
various
fluorenones
has
been
achieved
via
Rh(III)-catalyzed
C–H
activation/[4
+
2]
annulation/aromatization
sequences
simple
and
readily
available
enaminones
1,3-dienes.
This
protocol
showed
good
substrate
compatibility
as
an
array
structurally
electronically
diverse
prepared
efficiently
in
moderate
to
yields
preparative
scale
utility
showing
very
efficiency
the
late-stage
functionalization
complex
valuable
molecules.
Язык: Английский