Photoredox/Iron Dual-Catalysis-Enabled [4 + 2] Cyclization of Acyl Nitrene with Alkynes DOI
Shimin Xie,

Shuwang Tang,

Ming Hou

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Дек. 13, 2024

In this work, the annulation of acyl nitrene with alkynes is reported under photoredox/iron dual-catalysis for synthesis a series isoquninalin-2-ones. The reaction featured high regioselectivity and good generality. particular, resulting isoquinalin-2-ones could be structurally elaborated into several biologically interesting scaffolds. Mechanism investigation suggests that was ascribed to formal [4 + 2] cyclization. It believed represents an initial example preparing isoquinolin-1-ones from ferric peroxyl-catalyzed insertion.

Язык: Английский

Organo-mediator enabled electrochemical transformations DOI
Wei-Mei Zeng, Yanwei Wang,

Chunhui Peng

и другие.

Chemical Society Reviews, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

This review highlights organo-mediators that enable electrochemical reactions via outer-sphere electron transfer (ET), offering advantages such as availability, tunability, and simplified post-processing compared to direct electrolysis.

Язык: Английский

Процитировано

1

Electrosynthesis of 1,4-diene derivatives bearing cyclopentene skeleton DOI Creative Commons

Yaqi Qiao,

Xiaoqing Fan,

Chengcheng Yuan

и другие.

iScience, Год журнала: 2025, Номер 28(3), С. 111976 - 111976

Опубликована: Фев. 10, 2025

1,n-Dual Π systems including 1,4-diene derivatives have been widely used as the elegant radical receptors to promote cascade additions give highly functionalized polycyclic scaffolds. However, tedious and complicated preparation of former deters broad utilization compromises practical value. Herein, a straightforward was developed from easily accessible alkynes γ,δ-unsaturated carboxylic acids via electrochemical oxidation cyclization Hofmann elimination. This transformation features with good excellent yields, functional group compatibility, selectivity without any Zaitsev elimination product detected.

Язык: Английский

Процитировано

0

Electrochemical Continuous-Flow Scholl Reaction toward Polycyclic Aromatic Hydrocarbons DOI
Weizhen Wang, Qiang Wang,

Xinglei He

и другие.

Organic Letters, Год журнала: 2024, Номер 26(11), С. 2243 - 2248

Опубликована: Март 8, 2024

The preparation of polycyclic aromatic hydrocarbons (PAHs) by the Scholl reaction is typically performed using superstoichiometric oxidants. Herein, we develop an electrochemical continuous-flow to access PAHs that features a reduction in use supporting electrolytes and easy scale-up without changing conditions setups. This allows synthesis distorted containing three [5]helicene units possess intriguing electronic optical properties.

Язык: Английский

Процитировано

3

Electrosynthesis of 1,2,3‐Benzotriazines through an Iodide‐Catalyzed Skeletal Editing of 3‐Aminoindazoles DOI
Mrinmay Baidya, Suman De Sarkar

Chemistry - A European Journal, Год журнала: 2024, Номер unknown

Опубликована: Авг. 19, 2024

Abstract This report describes an environmentally benign synthesis of 1,2,3‐benzotriazines through iodide‐catalyzed electro‐oxidative N ‐centered [1,2]‐rearrangement 3‐aminoindazoles. The developed method demonstrates the activation heteroatoms via electrochemically generated reactive iodide species without using any metal catalysts and peroxides. protocol features practical mild reaction conditions displays a wide substrate scope. Various mechanistic experiments cyclic voltammetric studies have been instrumental in elucidating mechanism, operating skeletal rearrangement

Язык: Английский

Процитировано

1

Construction of N-Heterocycles via Electrochemically Generated Nitrogen Radicals and Nitrilium Ions DOI
Zhaojiang Shi, Ke‐Yin Ye

Topics in heterocyclic chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

1

De novo synthesis of 6-6-5 fused-systems through electrochemical decarboxylation and radical domino additions DOI

Chengcheng Yuan,

Guanru Liu,

Wenjing Guan

и другие.

Green Chemistry, Год журнала: 2024, Номер 26(19), С. 10308 - 10313

Опубликована: Янв. 1, 2024

An oxidant and quaternary ammonium salt-free electrosynthesis of 6-6-5 fused systems was developed with excellent atom step economy.

Язык: Английский

Процитировано

1

Photoredox/Iron Dual-Catalysis-Enabled [4 + 2] Cyclization of Acyl Nitrene with Alkynes DOI
Shimin Xie,

Shuwang Tang,

Ming Hou

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Дек. 13, 2024

In this work, the annulation of acyl nitrene with alkynes is reported under photoredox/iron dual-catalysis for synthesis a series isoquninalin-2-ones. The reaction featured high regioselectivity and good generality. particular, resulting isoquinalin-2-ones could be structurally elaborated into several biologically interesting scaffolds. Mechanism investigation suggests that was ascribed to formal [4 + 2] cyclization. It believed represents an initial example preparing isoquinolin-1-ones from ferric peroxyl-catalyzed insertion.

Язык: Английский

Процитировано

1