Advances in the selection of functional monomers for molecularly imprinted polymers: A review
Journal of Separation Science,
Год журнала:
2024,
Номер
47(16)
Опубликована: Авг. 1, 2024
Molecularly
imprinted
polymers,
a
type
of
special
polymer
materials,
are
widely
used
in
biosensing
and
other
fields
due
to
their
ability
specifically
recognize
target
molecules,
often
called
"artificial
receptors.".
Nowadays,
researchers
constantly
exploring
new
design
synthesis
methods
for
molecularly
materials
improve
the
selectivity
sensitivity
materials.
Among
them,
selection
functional
monomers
has
attracted
great
attention.
This
review
comprehensively
analyzes
discusses
monomers.
The
most
commonly
among
different
types
templates
screened
based
on
structural
properties
template
including
ion-imprinted
protein-imprinted
bacterial
polymers.
rich
binding
sites
group
multifunctional
also
highlighted
advance
development
molecular
imprinting
technology.
article
further
explores
current
challenges
prospects
emphasizes
multiplex
experiments
computer
simulations
as
important
directions
future
research.
provides
comprehensive
information
constructive
guidelines
selecting
areas
such
analytical
chemistry
biosensors.
Язык: Английский
A Systematic Study of Liquid Chromatography in Search of the Best Separation of Cannabinoids for Potency Testing of Hemp-Based Products
Ayowole Owolabi,
Olalekan Ogunsola,
Emma Joens
и другие.
Molecules,
Год журнала:
2025,
Номер
30(4), С. 758 - 758
Опубликована: Фев. 7, 2025
A
study
was
conducted
to
search
for
the
best
separation
of
eighteen
cannabinoids,
maximum
number
cannabinoids
that
have
been
quantified
so
far,
potency
testing
hemp-based
products
using
liquid
chromatography
diode
array
detector
(LC-DAD).
The
investigation
utilized
four
column
types,
all
sharing
same
dimension
(150
mm
×
2.1
mm)
and
core-shell
particle
size
(2.7
µm),
but
different
stationary
phases:
dimethyl-octadecyl
(Poroshell
120
EC-C18),
diisobutyl-octadecyl
(Raptor
ARC-18),
reverse
phase
(RP)-carbamate
(Cortecs
Shield
RP-18),
RP-amide
(Ascentis
Express
RP-Amide).
resolution
adjacent
kept
close
1.5
or
higher,
while
time
as
short
possible.
fastest
achieved
within
15.0
min
two
sequential
Raptor
ARC-18
columns,
with
a
mobile
consisting
75.0%
acetonitrile
25.0%
aqueous
solution
0.03%
formic
acid
0.5
mM
ammonium
formate
at
pH
2.97,
flow
rate
mL/min.
slightly
improved
obtained
18.5
Poroshell
EC-C18
columns
under
similar
conditions,
except
containing
77.5%
reduced
0.45
mL/min
due
backpressure
higher
than
600
bars.
Furthermore,
rapid
7.0
by
electrospray
ionization
tandem
mass
spectrometry
(LC-ESI/MS/MS)
Cortecs
RP-18
column,
70.0%
30.0%
0.01%
1
3.38
Язык: Английский
Highly Sensitive Oxytetracycline Detection Using QCM and Molecularly Imprinted Polymers with Deep Eutectic Solvents
Polymers,
Год журнала:
2025,
Номер
17(7), С. 946 - 946
Опубликована: Март 31, 2025
This
study
presents
an
efficient
method
for
detecting
oxytetracycline,
which
is
critical
in
environmental
monitoring
and
food
safety.
A
highly
sensitive
detection
platform
was
developed
by
combining
molecularly
imprinted
polymers
(MIPs)
with
silica
as
a
carrier,
modified
deep
eutectic
solvents
(DES),
quartz
crystal
microbalance
(QCM)
sensor.
The
MIPs
were
specifically
designed
to
target
oxytetracycline
hydrochloride,
using
SiO2
the
DES
functional
monomer,
N,
N-methylenebisacrylamide
crosslinker,
ammonium
persulfate
initiator.
exhibited
adsorption
capacity
of
27.23
mg/g
hydrochloride.
After
modification
onto
gold
electrode
surface,
QCM-based
sensor
constructed.
demonstrated
exceptionally
low
limit
0.019
ng/mL
excellent
sensitivity
tap
water.
Furthermore,
maintained
over
90%
performance
after
two
weeks
room-temperature
storage,
indicating
its
stability.
provides
rapid,
approach
detection,
potential
future
improvements
widespread
application
antibiotic
testing.
Язык: Английский