Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends

Frontiers in Pharmacology, Год журнала: 2025, Номер 15

Опубликована: Янв. 8, 2025

The application of nanomedicine in inflammatory bowel disease (IBD) has gained significant attention the recent years. As field rapidly evolves, analyzing research trends and identifying hotpots are essential for guiding future advancements, a comprehensive bibliometric can provide valuable insights. current focused on publications from 2001 to 2024, was sourced Web Science Core Collection (WoSCC). CiteSpace VOSviewer were employed visualize authors, institutions, countries, co-cited references, keywords, thereby mapping intellectual structure emerging field. analysis covered 1,518 literature across 447 journals, authored by 9,334 researchers 5,459 institutions 287 countries/regions. global publication numbers exhibited an upward trend, particularly last decade, with China leading as top publishing country Chinese Academy Sciences foremost institution. Dr. Xiao Bo is prominent figure advanced drug delivery systems. This interdisciplinary field, which spans materials science, pharmacy, medicine, seen influential mainly concentrated targeted nanoparticles treatment IBD. Keyword revealed that hotspots include delivery, immune cell regulation, antioxidant damage, intestinal microbiota homeostasis, nanovesicles. study offers overview landscape, emphasizing rapid growth increasing complexity this It identifies key trends, including efforts enhance precision, efficacy, safety applications. Emerging directions highlighted crucial further progress evolving area.

Язык: Английский

Cutting-edge insights into the mechanistic understanding of plant-derived exosome-like nanoparticles: Implications for intestinal homeostasis

Food Research International, Год журнала: 2025, Номер unknown, С. 116186 - 116186

Опубликована: Март 1, 2025

Язык: Английский

Dietary Lactobacillus johnsonii-derived extracellular vesicles ameliorate acute colitis by regulating gut microbiota and maintaining intestinal barrier homeostasis

Food & Function, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Lactobacillus johnsonii -derived extracellular vesicles (LJ-EVs) improve gut microbiota disruption and metabolism in colitis mice, while activating the Nrf2/HO-1 antioxidant signaling pathway to maintain intestinal barrier homeostasis.

Язык: Английский