Programmable Strategies for the Conversion of Aldehydes to Unsymmetrical (Deuterated) Diarylmethanes and Diarylketones

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Март 28, 2025

Herein, we present a versatile method for synthesizing unsymmetrical diarylmethanes and diarylketones from aldehydes arenes. This involves: (1) regioselective Ar-H alkylation to form benzhydrylphosphonium salts via one-pot, four-component reaction with simple reagents (2) chemoselective reductions or oxidations of the benzylic C-P bond. Notably, D2O yield fully deuterated diarylmethanes. high-yielding, straightforward approach offers valuable building blocks enables novel transformations academic pharmaceutical research.

Язык: Английский

Efficient single-component nickel catalysts with tetradentate aminopyridine ligands for cycloaddition reactions of CO₂ and epoxides under mild conditions

RSC Sustainability, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A series of single-component nickel catalysts with tetradentate aminopyridine ligands exhibited excellent capabilities and selectivity for the synthesis cyclic carbonates from epoxides CO 2 , even under 1 atm 0.5 mol% catalyst.

Язык: Английский