Base‐free Synthesis of S‐Alkyl Isothioureas Through Ring‐opening Reaction of Sulfonium Salts with Isothiocyanates and Amines DOI
Cunwei Qian, Wei Xiang,

Meng-Qing Gu

и другие.

Chemistry - A European Journal, Год журнала: 2024, Номер 31(8)

Опубликована: Дек. 6, 2024

A convenient and base-free three-component reaction has been developed for the synthesis of S-alkyl substituted isothioureas from cyclic sulfonium salts, isothiocyanates, amines. This protocol provides an alternative avenue to access a series in moderate good yields through ring-opening aryl, alkenyl alkynyl salts. The present strategy features operational simplicity, functional group tolerance, gram-scale high efficiency.

Язык: Английский

Visible-Light-Induced Phosphorothioation of Alkenyl Sulfonium Salts with S8 and H-Phosphonates DOI
Lihua Yang,

Ni-Dan Meng,

Li Tang

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 4, 2025

An efficient and practical method for synthesizing vinyl phosphorothioates has been demonstrated through a visible-light-induced three-component reaction of alkenyl sulfonium salts, S8, H-phosphonates. This facilitates the synthesis diverse range with wide substrate scope functional group tolerance. Preliminary mechanistic studies suggest that involves phosphorothioate radical-triggered process.

Язык: Английский

Процитировано

0

Manual Grinding and Sunlight Synergistically Promoted Sulfonylation of Alkenyl Sulfonium Salts with Sulfinic Acids DOI
Lihua Yang, Lin Chen, Weijun Yao

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 10, 2025

An environmentally friendly and practical method for the synthesis of various vinyl sulfones was developed through direct sulfonylation alkenyl sulfonium salts with sulfinic acids. The reaction effectively triggered by combined actions milling, sunlight, photocatalysts under solvent-free conditions, offering advantages such as a short time (5-10 min), room temperature, straightforward workup procedure. Preliminary mechanistic studies suggested that sulfonyl radical may be involved in this mechanophotocatalytic transformation process.

Язык: Английский

Процитировано

0

New Frontiers in Phosphorothioate Formation: Harnessing Inorganic Phosphorus Sources DOI
Jiawei He,

Xuesi Zhou,

Zixuan Wan

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(99), С. 14691 - 14702

Опубликована: Янв. 1, 2024

This review highlights the latest advancements in synthesis of phosphorothioates and their derivatives from inorganic phosphorus sources, focusing on applicability, mechanisms, current limitations, potential future directions.

Язык: Английский

Процитировано

0

Base‐free Synthesis of S‐Alkyl Isothioureas Through Ring‐opening Reaction of Sulfonium Salts with Isothiocyanates and Amines DOI
Cunwei Qian, Wei Xiang,

Meng-Qing Gu

и другие.

Chemistry - A European Journal, Год журнала: 2024, Номер 31(8)

Опубликована: Дек. 6, 2024

A convenient and base-free three-component reaction has been developed for the synthesis of S-alkyl substituted isothioureas from cyclic sulfonium salts, isothiocyanates, amines. This protocol provides an alternative avenue to access a series in moderate good yields through ring-opening aryl, alkenyl alkynyl salts. The present strategy features operational simplicity, functional group tolerance, gram-scale high efficiency.

Язык: Английский

Процитировано

0