Exploration of the VEGFR-2 inhibition activity of phthalazine derivatives: design, synthesis, cytotoxicity, ADMET, molecular docking and dynamic simulation
RSC Advances,
Год журнала:
2024,
Номер
14(30), С. 21668 - 21681
Опубликована: Янв. 1, 2024
Novel
phthalazine
derivatives
were
designed,
synthesized
and
evaluated
against
Hep
G2
MCF-7
as
VEGFR-2
inhibitors.
Язык: Английский
Rational design, docking, syntheses, ADMET and cytotoxicity assessments of iodoquinazoline derivatives as inhibitors of EGFRT790M and VEGFR-2
Journal of Molecular Structure,
Год журнала:
2025,
Номер
unknown, С. 141634 - 141634
Опубликована: Янв. 1, 2025
Язык: Английский
Antibacterial and anti-tumor properties of marine posidonoia oceanica leaf extracts
Journal of Herbs Spices & Medicinal Plants,
Год журнала:
2025,
Номер
unknown, С. 1 - 23
Опубликована: Март 17, 2025
Язык: Английский
Rationale, in silico docking, ADMET profile, design, synthesis and cytotoxicity evaluations of phthalazine derivatives as VEGFR-2 inhibitors and apoptosis inducers
RSC Advances,
Год журнала:
2024,
Номер
14(37), С. 27110 - 27121
Опубликована: Янв. 1, 2024
New
phthalazine
derivatives
as
vascular
endothelial
growth
factor
receptor-2
(VEGFR-2)
inhibitors
were
synthesized
joined
to
different
spacers
including
pyrazole,
α,β-unsaturated
ketonic
fragment,
pyrimidinone
and/or
pyrimidinthione.
Язык: Английский
Exploration of cytotoxicity of iodoquinazoline derivatives as inhibitors of both VEGFR‐2 and EGFRT790M: Molecular docking, ADMET, design, and syntheses
Archiv der Pharmazie,
Год журнала:
2024,
Номер
357(11)
Опубликована: Авг. 1, 2024
Novel
inhibitors
of
epidermal
growth
factor
receptor
(EGFR)
Язык: Английский