Application and progress of smart hydrogel microspheres for regulating oxidative stress in osteoarthritis
Chemical Engineering Journal,
Год журнала:
2025,
Номер
unknown, С. 160620 - 160620
Опубликована: Фев. 1, 2025
Язык: Английский
Targeted drug delivery systems for atherosclerosis
Journal of Nanobiotechnology,
Год журнала:
2025,
Номер
23(1)
Опубликована: Апрель 23, 2025
Atherosclerosis
is
a
complex
cardiovascular
disease
driven
by
multiple
factors,
including
aging,
inflammation,
oxidative
stress,
and
plaque
rupture.
The
progression
of
this
often
covert,
emphasizing
the
need
for
early
biomarkers
effective
intervention
measures.
In
recent
years,
advancements
in
therapeutic
strategies
have
highlighted
potential
targeting
specific
processes
atherosclerosis,
such
as
localization,
macrophage
activity,
key
enzymes.
Based
on
this,
review
discusses
role
targeted
drugs
treatment
atherosclerosis.
It
also
focuses
their
clinical
efficacy
anti-atherosclerosis
ability
to
provide
more
precise
approaches.
findings
underscore
that
future
research
can
concentrate
exploring
newer
drug
delivery
systems
further
refine
enhance
long-term
dynamic
management
Язык: Английский
Nanozyme-based therapeutic strategies for rheumatoid arthritis
Journal of Controlled Release,
Год журнала:
2024,
Номер
377, С. 716 - 734
Опубликована: Дек. 3, 2024
Язык: Английский
Heterojunction Nanozyme Hydrogels Containing Cu–O–Zn Bonds with Strong Charge Transfer for Accelerated Diabetic Wound Healing
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 4, 2024
The
complex
microenvironment
of
persistent
inflammation
and
bacterial
infection
is
a
major
challenge
in
chronic
diabetic
wounds.
development
nanozymes
capable
efficiently
scavenging
reactive
oxygen
species
(ROS)
promising
method
to
promote
wound
healing.
However,
many
show
rather
limited
antioxidant
activity
ROS-dependent
antibacterial
effects
under
certain
circumstances,
further
weakening
their
ability
scavenge
ROS.
To
meet
these
challenges,
electronically
regulated
bioheterojunction
(E-bio-HJ)
nanozyme
hydrogels
derived
from
metal-organic
frameworks
(MOFs)
were
designed
prepared
via
an
interface
engineering
strategy.
Owing
the
electron
transfer
redistribution
abundant
highly
dispersed
Cu-O-Zn
sites
at
heterogeneous
interface,
E-bio-HJ
exhibited
catalase
(CAT)-like
with
ultrahigh
hydrogen
peroxide
affinity
(
Язык: Английский
Nanotechnology-Assisted mesenchymal stem cells treatment for improved cartilage regeneration: A review of current practices
Biochemical Pharmacology,
Год журнала:
2025,
Номер
unknown, С. 116895 - 116895
Опубликована: Март 1, 2025
Язык: Английский
Catalytic Nanozyme: Unlocking new horizons in articular cartilage degeneration treatment
Coordination Chemistry Reviews,
Год журнала:
2025,
Номер
541, С. 216845 - 216845
Опубликована: Май 29, 2025
Язык: Английский
Mechanism and Application of Biomaterials Targeting Reactive Oxygen Species and Macrophages in Inflammation
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
26(1), С. 245 - 245
Опубликована: Дек. 30, 2024
Inflammation,
an
adaptive
reaction
to
harmful
stimuli,
is
a
necessary
immune
system
response
and
can
be
either
acute
or
chronic.
Since
inflammation
tends
eliminate
stimuli
restore
equilibrium,
it
generally
advantageous
the
organism.
Chronic
inflammation,
however,
caused
by
increased
inflammatory
signaling
decreased
pro-anti-inflammatory
signaling.
According
current
studies,
thought
major
factor
in
number
of
chronic
diseases,
including
diabetes,
cancer,
arthritis,
bowel
disease,
obesity.
Consequently,
reducing
essential
for
both
preventing
delaying
diseases.
The
application
biomaterials
treatment
illnesses
has
grown
recent
years.
A
variety
implanted
themselves
conjunction
with
other
bioactive
ingredients
therapeutic
agents.
mechanisms
action
applications
well-known
anti-inflammatory
are
main
topics
this
article.
Язык: Английский