Mechanism and Application of Biomaterials Targeting Reactive Oxygen Species and Macrophages in Inflammation DOI Open Access
Megan Yu,

Shouli Wang,

Doudou Lin

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 26(1), P. 245 - 245

Published: Dec. 30, 2024

Inflammation, an adaptive reaction to harmful stimuli, is a necessary immune system response and can be either acute or chronic. Since inflammation tends eliminate stimuli restore equilibrium, it generally advantageous the organism. Chronic inflammation, however, caused by increased inflammatory signaling decreased pro-anti-inflammatory signaling. According current studies, thought major factor in number of chronic diseases, including diabetes, cancer, arthritis, bowel disease, obesity. Consequently, reducing essential for both preventing delaying diseases. The application biomaterials treatment illnesses has grown recent years. A variety implanted themselves conjunction with other bioactive ingredients therapeutic agents. mechanisms action applications well-known anti-inflammatory are main topics this article.

Language: Английский

Application and progress of smart hydrogel microspheres for regulating oxidative stress in osteoarthritis DOI
Jinping Chen, Chengcheng Du, Bin Tang

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160620 - 160620

Published: Feb. 1, 2025

Language: Английский

Citations

0
Nanotechnology-Assisted mesenchymal stem cells treatment for improved cartilage regeneration: A review of current practices DOI

Hongming Lin,

Chao Zhou, Qingping Li

et al.

Biochemical Pharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 116895 - 116895

Published: March 1, 2025

Language: Английский

Citations

0
Targeted drug delivery systems for atherosclerosis DOI Creative Commons
Liangxing Tu,

Zijian Zou,

Yang Ye

et al.

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 23, 2025

Atherosclerosis is a complex cardiovascular disease driven by multiple factors, including aging, inflammation, oxidative stress, and plaque rupture. The progression of this often covert, emphasizing the need for early biomarkers effective intervention measures. In recent years, advancements in therapeutic strategies have highlighted potential targeting specific processes atherosclerosis, such as localization, macrophage activity, key enzymes. Based on this, review discusses role targeted drugs treatment atherosclerosis. It also focuses their clinical efficacy anti-atherosclerosis ability to provide more precise approaches. findings underscore that future research can concentrate exploring newer drug delivery systems further refine enhance long-term dynamic management

Language: Английский

Citations

0
Nanozyme-based therapeutic strategies for rheumatoid arthritis DOI

Jucong Zhang,

Chenxi Wang,

Xiaochuan Wu

et al.

Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 377, P. 716 - 734

Published: Dec. 3, 2024

Language: Английский

Citations

2
Heterojunction Nanozyme Hydrogels Containing Cu–O–Zn Bonds with Strong Charge Transfer for Accelerated Diabetic Wound Healing DOI

Qiujiang Li,

Xuanyu Xiao,

Tianyou Yan

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 4, 2024

The complex microenvironment of persistent inflammation and bacterial infection is a major challenge in chronic diabetic wounds. development nanozymes capable efficiently scavenging reactive oxygen species (ROS) promising method to promote wound healing. However, many show rather limited antioxidant activity ROS-dependent antibacterial effects under certain circumstances, further weakening their ability scavenge ROS. To meet these challenges, electronically regulated bioheterojunction (E-bio-HJ) nanozyme hydrogels derived from metal-organic frameworks (MOFs) were designed prepared via an interface engineering strategy. Owing the electron transfer redistribution abundant highly dispersed Cu-O-Zn sites at heterogeneous interface, E-bio-HJ exhibited catalase (CAT)-like with ultrahigh hydrogen peroxide affinity (

Language: Английский

Citations

2
Mechanism and Application of Biomaterials Targeting Reactive Oxygen Species and Macrophages in Inflammation DOI Open Access
Megan Yu,

Shouli Wang,

Doudou Lin

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 26(1), P. 245 - 245

Published: Dec. 30, 2024

Inflammation, an adaptive reaction to harmful stimuli, is a necessary immune system response and can be either acute or chronic. Since inflammation tends eliminate stimuli restore equilibrium, it generally advantageous the organism. Chronic inflammation, however, caused by increased inflammatory signaling decreased pro-anti-inflammatory signaling. According current studies, thought major factor in number of chronic diseases, including diabetes, cancer, arthritis, bowel disease, obesity. Consequently, reducing essential for both preventing delaying diseases. The application biomaterials treatment illnesses has grown recent years. A variety implanted themselves conjunction with other bioactive ingredients therapeutic agents. mechanisms action applications well-known anti-inflammatory are main topics this article.

Language: Английский

Citations

1