Biowaste Transformation to Functional Materials: Structural Properties, Extraction Methods, Applications, and Challenges of Silk Sericin
Mohashin Kabir,
Mohammed Kamrul Hasan,
Mohamad Rafi
и другие.
ChemistrySelect,
Год журнала:
2024,
Номер
9(42)
Опубликована: Ноя. 1, 2024
Abstract
This
review
underscores
the
novelty
of
silk
sericin,
often
regarded
as
a
byproduct
in
production.
Comprising
approximately
30%
silk,
sericin
possesses
valuable
properties
that
have
been
largely
overlooked
favor
fibroin.
work
focuses
on
innovative
extraction
methods
to
convert
typically
considered
waste,
into
resource.
By
examining
these
techniques
alongside
diverse
applications,
aims
enhance
recognition
and
utilization
research
industry.
Various
processes
where
traditional
methods,
some
new
techniques,
are
all
discussed.
In
detail,
advantages,
limitations,
strategy
optimization
associated
with
each
method
highlighted.
For
instance,
has
shown
promise
wound
treatment
agent,
scaffold
for
tissue
engineering,
carrier
drug
delivery,
biomaterial
regenerative
medicine
field
biomedical
science
due
its
biocompatibility,
biodegradability,
nontoxicity.
Additionally,
it
also
finds
application
cosmetic
industry,
is
used
skincare
products
moisturizing,
antioxidant,
antiaging
properties.
Eventually,
challenges,
prospects
intensively
comprehensive
expected
serve
growing
body
knowledge
surrounding
foster
further
development
sericin‐related
fields.
Язык: Английский
Innovative Processing and Sterilization Techniques to Unlock the Potential of Silk Sericin for Biomedical Applications
Gels,
Год журнала:
2025,
Номер
11(2), С. 114 - 114
Опубликована: Фев. 6, 2025
Silk
sericin
(SS),
a
by-product
of
the
textile
industry,
has
gained
significant
attention
for
its
biomedical
potential
due
to
biocompatibility
and
regenerative
potential.
However,
literature
lacks
information
on
SS
processing
methods
resulting
physicochemical
properties.
This
study
represents
first
step
in
protocol
optimization
standardization.
In
present
work,
different
techniques
were
studied
compared
extracted
from
boiling
water:
evaporation,
rotary
lyophilization,
dialysis,
which
presented
recovery
yield
approximately
27–32%.
The
goal
was
find
most
promising
process
concentrate
solutions,
ensure
that
structure
highly
preserved.
As
result,
new
cryo-lyophilization
methodology
proposed.
proposed
method
allows
preservation
amorphous
structure,
offers
advantages
including
complete
dissolution
water
PBS,
an
increase
storage
stability,
possibility
scaling-up,
making
it
suitable
industrial
applications.
second
part
work
focused
addressing
another
challenge
processing:
efficient
non-destructive
sterilization.
Supercritical
CO2
(scCO2)
been
gaining
momentum
last
years
sterilizing
sensitive
biopolymers
biological
materials
non-toxicity
mild
conditions.
Thus,
scCO2
technology
validated
as
technique
terminal
sterilization
SS.
this
way,
possible
engineer
sequential
cryo-lyophilization/scCO2
able
preserve
original
properties
natural
silk
protein.
Overall,
we
have
valorized
into
sterile,
off-the-shelf,
bioactive,
water-soluble
material,
with
be
used
biomedical,
pharmaceutical,
or
cosmetic
industries.
Язык: Английский
Native Silk Fibers: Protein Sequence and Structure Influences on Thermal and Mechanical Properties
Biomacromolecules,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 7, 2025
Silk
fibers
produced
by
arthropods
have
inspired
an
array
of
materials
with
applications
in
healthcare,
medical
devices,
textiles,
and
sustainability.
Silks
exhibit
biodiversity
distinct
variations
primary
protein
constituent
sequences
(fibroins,
spidroins)
structures
across
taxonomic
classifications,
specifically
the
Lepidopteran
Araneae
orders.
Leveraging
arthropod
silks
offers
advantages
due
to
diverse
mechanical
properties
thermal
stabilities
achievable,
primarily
attributed
fiber
crystallinity
repeating
amino
acid
motifs.
In
this
review,
we
aim
delineate
known
silk
correlate
them
predicted
secondary
structures,
informed
newly
annotated
genomes.
We
will
discuss
established
patterns
repeat
motifs
governing
specific
underscore
biological
diversity
within
fibroin
spidroin
sequences.
Elucidating
relationship
between
natural
identify
strategies
for
designing
new
through
rational
silk-based
design.
Язык: Английский
Recent advancements and challenges in 3D bioprinting for cancer applications
Bioprinting,
Год журнала:
2024,
Номер
43, С. e00357 - e00357
Опубликована: Сен. 13, 2024
Язык: Английский
Biogenic gold nanoparticles stabilized with silk sericin and their impacts on osteogenic induction and surface modification of polymethyl methacrylate
Applied Surface Science,
Год журнала:
2024,
Номер
unknown, С. 161591 - 161591
Опубликована: Окт. 1, 2024
Язык: Английский
Silk Sericin/Chitosan Supramolecular Multilayered Thin Films as Sustainable Cytocompatible Nanobiomaterials
Biomacromolecules,
Год журнала:
2024,
Номер
26(1), С. 296 - 310
Опубликована: Дек. 16, 2024
Silk
sericin
(SS)
has
been
widely
discarded
as
a
waste
by
the
silk
textile
industry
during
degumming
process
to
obtain
fibroin.
However,
in
past
decade,
an
in-depth
understanding
of
its
properties
and
functions
turned
it
into
high
added-value
biomaterial
for
biomedical
applications.
Herein,
we
report
molecular
design
development
sustainable
supramolecular
multilayered
nanobiomaterials
encompassing
SS
oppositely
charged
chitosan
(CHT)
through
combination
self-assembly
electrostatically
driven
layer-by-layer
(LbL)
assembly
technology.
The
successful
buildup
SS/CHT
was
demonstrated
quartz
crystal
microbalance
with
dissipation
monitoring
attenuated
total
reflectance-Fourier
transform
infrared
spectroscopy,
nanofilms'
wettable
nanofibrillar-like
topography
were
shown
water
contact
angle,
atomic
force
microscopy,
scanning
electron
microscopy.
In
vitro
assays
cytocompatibility
LbL
nanofilms
toward
human
primary
dermal
fibroblasts,
holding
great
promise
biofunctional
nanocoatings
drug/therapeutics/cell
delivery,
tissue
engineering,
regenerative
medicine.
Язык: Английский