Marine natural products
Natural Product Reports,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
A
comprehensive
review
of
1220
new
MNPs
including
a
novel
sex
inducing
pheromone
from
the
diatom
Seminavis
robusta
.
Язык: Английский
Corey–Fuchs reaction enabled synthesis of natural products: a review
RSC Advances,
Год журнала:
2025,
Номер
15(11), С. 8121 - 8155
Опубликована: Янв. 1, 2025
Corey–Fuchs
reaction
is
a
two-step
involving
the
synthesis
of
terminal
alkyne
from
aldehyde.
It
pivotal
organic
reaction,
plays
significant
role
in
various
natural
products
and
their
derivatives.
Язык: Английский
Regiodivergent Synthesis of Oxadiazocines via Dirhodium-Catalyzed Reactivity of Oxazolidines and α-Imino Carbenes
Synlett,
Год журнала:
2023,
Номер
34(12), С. 1472 - 1476
Опубликована: Апрель 12, 2023
Abstract
Using
electron-rich
or
electron-poor
N-substituted
oxazolidines
as
substrates,
selective
formation
of
either
ammonium
oxonium
ylides
is
possible
in
the
presence
α-imino
carbenes.
As
such,
treatment
5-membered
oxazolidine
precursors
with
N-sulfonyl-1,2,3-triazoles
under
dirhodium
catalysis
(2
mol%)
affords
regiodivergent
synthesis
8-membered
1,3,6-
1,4,6-oxadiazocines
upon
initial
N
O
reactivity
carbene.
Язык: Английский
Total Synthesis of (–)-Rauvomine B via a Strain-Promoted Intramolecular Cyclopropanation
Опубликована: Май 21, 2024
We
describe
the
first
total
synthesis
of
unusual
cyclopropane-containing
indole
alkaloid
(–)-rauvomine
B
via
a
strategy
centered
upon
intramolecular
cyclopropanation
tetracyclic
N-sulfonyl
triazole.
Preparation
this
precursor
evolved
through
two
generations
synthesis,
with
ultimately
successful
route
involving
palladium-catalyzed
stereospecific
allylic
amination,
cis-selective
Pictet–Spengler
reaction,
and
ring-closing
metathesis
as
important
bond-forming
reactions.
The
key
step
was
found
to
be
highly
dependent
on
structure
conformational
strain
indoloquinolizidine
triazole
precursor,
origins
which
are
explored
computationally
DFT
studies.
Overall,
our
proceeds
in
11
steps
2.4%
yield
from
commercial
materials.
Язык: Английский
Total Synthesis of (–)-Rauvomine B via a Strain-Promoted Intramolecular Cyclopropanation
Опубликована: Май 29, 2024
We
describe
the
first
total
synthesis
of
unusual
cyclopropane-containing
indole
alkaloid
(–)-rauvomine
B
via
a
strategy
centered
upon
intramolecular
cyclopropanation
tetracyclic
N-sulfonyl
triazole.
Preparation
this
precursor
evolved
through
two
generations
synthesis,
with
ultimately
successful
route
involving
palladium-catalyzed
stereospecific
allylic
amination,
cis-selective
Pictet–Spengler
reaction,
and
ring-closing
metathesis
as
important
bond-forming
reactions.
The
key
step
was
found
to
be
highly
dependent
on
structure
conformational
strain
indoloquinolizidine
triazole
precursor,
origins
which
are
explored
computationally
DFT
studies.
Overall,
our
proceeds
in
11
steps
2.4%
yield
from
commercial
materials.
Язык: Английский
Total Synthesis of (−)-Rauvomine B via a Strain-Promoted Intramolecular Cyclopropanation
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(31), С. 22047 - 22055
Опубликована: Июль 23, 2024
We
describe
the
first
total
synthesis
of
unusual
cyclopropane-containing
indole
alkaloid
(-)-rauvomine
B
via
a
strategy
centered
upon
intramolecular
cyclopropanation
tetracyclic
Язык: Английский
Five-membered ring systems: With more than 1 N atom
Progress in heterocyclic chemistry,
Год журнала:
2024,
Номер
unknown, С. 211 - 257
Опубликована: Янв. 1, 2024
Язык: Английский
Insertion of Azavinyl Carbenes to CH/ X H Bond
Опубликована: Ноя. 22, 2024
The
chapter
represents
a
comprehensive
review
on
C/
X
H
insertion
reactions
of
azavinyl
carbenes
or
carbenoids,
generated
from
diazoimine
form
N
1-sulfonyl-1,2,3-triazoles.
Various
cascade
transformations
and
rearrangements
triggered
by
the
initial
carbene
are
considered.
literature
is
classified
according
to
type
bond
(CH,
OH,
NH,
etc.)
involved
in
reaction.
last
section
devoted
denitrogenative
insertions
nucleophile-tethered
5-iodotriazoles
demonstrating
reactivity
upon
annulation.
Язык: Английский
Cluster Preface: Special Issue Honoring Masahiro Murakami’s Contributions to Science
Synlett,
Год журнала:
2023,
Номер
34(12), С. 1285 - 1288
Опубликована: Июнь 28, 2023
Abstract
Ruben
Martin
(left)
was
born
in
Barcelona
1976.
After
receiving
his
PhD
at
the
Universitat
de
with
Prof.
Antoni
Riera,
he
moved
January
2004
to
Max-Planck-Institut
für
Kohlenforschung,
Mülheim,
as
a
Humboldt
postdoctoral
fellow
Alois
Fürstner,
where
worked
on
iron
cross-coupling
reactions.
In
May
2005,
undertook
further
studies
Massachusetts
Institute
of
Technology
Stephen
L.
Buchwald
developed
new
metal-catalyzed
C–C
and
C–N
bond-forming
September
2008,
initiated
independent
career
an
Assistant
Professor
ICIQ
(Tarragona).
July
2013,
promoted
Associate
subsequently
ICREA
Research
Professor.
His
research
interests
concern
discovery
development
synthetically
useful
organometallic
methodologies.
Masahiro
Murakami
(right)
studied
chemistry
University
Tokyo
under
supervision
Mukaiyama,
doctoral
degree
science
1984.
He
started
assistant
position
Mukaiyama
same
place.
1987,
Kyoto
take
late
Yoshihiko
Ito
(1937–2006).
took
leave
from
1991
March
1992
work
for
Albert
Eschenmoser
ETH
Zürich
post-doctoral
fellow.
then
returned
Kyoto,
being
1993
2002.
2022,
retired
University.
include
useful,
yet
mechanistically
interesting,
organic
sections,
utilization
photo-energy
synthesis.
Язык: Английский