Cluster Preface: Special Issue Honoring Masahiro Murakami’s Contributions to Science DOI Open Access
Rubén Martı́n

Synlett, Journal Year: 2023, Volume and Issue: 34(12), P. 1285 - 1288

Published: June 28, 2023

Abstract Ruben Martin (left) was born in Barcelona 1976. After receiving his PhD at the Universitat de with Prof. Antoni Riera, he moved January 2004 to Max-Planck-Institut für Kohlenforschung, Mülheim, as a Humboldt postdoctoral fellow Alois Fürstner, where worked on iron cross-coupling reactions. In May 2005, undertook further studies Massachusetts Institute of Technology Stephen L. Buchwald developed new metal-catalyzed C–C and C–N bond-forming September 2008, initiated independent career an Assistant Professor ICIQ (Tarragona). July 2013, promoted Associate subsequently ICREA Research Professor. His research interests concern discovery development synthetically useful organo­metallic methodologies. Masahiro Murakami (right) studied chemistry University ­Tokyo under supervision Mukaiyama, doctoral degree science 1984. He started assistant position Mukaiyama same place. 1987, Kyoto take late Yoshihiko Ito (1937–2006). took leave from 1991 March 1992 work for Albert Eschenmoser ETH Zürich post-doctoral fellow. then returned Kyoto, being 1993 2002. 2022, retired University. include useful, yet mechanistically interesting, organic sections, utilization photo-energy synthesis.

Language: Английский

Marine natural products DOI Creative Commons
Anthony R. Carroll, Brent R. Copp, Tanja Grkovic

et al.

Natural Product Reports, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A comprehensive review of 1220 new MNPs including a novel sex inducing pheromone from the diatom Seminavis robusta .

Language: Английский

Citations

3
Corey–Fuchs reaction enabled synthesis of natural products: a review DOI Creative Commons

Rabia Ashraf,

Ameer Fawad Zahoor,

Samreen Gul Khan

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(11), P. 8121 - 8155

Published: Jan. 1, 2025

Corey–Fuchs reaction is a two-step involving the synthesis of terminal alkyne from aldehyde. It pivotal organic reaction, plays significant role in various natural products and their derivatives.

Language: Английский

Citations

0
Regiodivergent Synthesis of Oxadiazocines via Dirhodium-Catalyzed Reactivity of Oxazolidines and α-Imino Carbenes DOI
Jérôme Lacour,

Olivier Viudes,

Alejandro Guarnieri‐Ibáñez

et al.

Synlett, Journal Year: 2023, Volume and Issue: 34(12), P. 1472 - 1476

Published: April 12, 2023

Abstract Using electron-rich or electron-poor N-substituted oxazolidines as substrates, selective formation of either ammonium oxonium ylides is possible in the presence α-imino carbenes. As such, treatment 5-membered oxazolidine precursors with N-sulfonyl-1,2,3-triazoles under dirhodium catalysis (2 mol%) affords regiodivergent synthesis 8-membered 1,3,6- 1,4,6-oxadiazocines upon initial N O reactivity carbene.

Language: Английский

Citations

4
Total Synthesis of (–)-Rauvomine B via a Strain-Promoted Intramolecular Cyclopropanation DOI Creative Commons

Jake Aquilina,

Ankush Banerjee,

Gabriel N. Morais

et al.

Published: May 21, 2024

We describe the first total synthesis of unusual cyclopropane-containing indole alkaloid (–)-rauvomine B via a strategy centered upon intramolecular cyclopropanation tetracyclic N-sulfonyl triazole. Preparation this precursor evolved through two generations synthesis, with ultimately successful route involving palladium-catalyzed stereospecific allylic amination, cis-selective Pictet–Spengler reaction, and ring-closing metathesis as important bond-forming reactions. The key step was found to be highly dependent on structure conformational strain indoloquinolizidine triazole precursor, origins which are explored computationally DFT studies. Overall, our proceeds in 11 steps 2.4% yield from commercial materials.

Language: Английский

Citations

1
Total Synthesis of (–)-Rauvomine B via a Strain-Promoted Intramolecular Cyclopropanation DOI Creative Commons

Jake Aquilina,

Ankush Banerjee,

Gabriel N. Morais

et al.

Published: May 29, 2024

We describe the first total synthesis of unusual cyclopropane-containing indole alkaloid (–)-rauvomine B via a strategy centered upon intramolecular cyclopropanation tetracyclic N-sulfonyl triazole. Preparation this precursor evolved through two generations synthesis, with ultimately successful route involving palladium-catalyzed stereospecific allylic amination, cis-selective Pictet–Spengler reaction, and ring-closing metathesis as important bond-forming reactions. The key step was found to be highly dependent on structure conformational strain indoloquinolizidine triazole precursor, origins which are explored computationally DFT studies. Overall, our proceeds in 11 steps 2.4% yield from commercial materials.

Language: Английский

Citations

1
Total Synthesis of (−)-Rauvomine B via a Strain-Promoted Intramolecular Cyclopropanation DOI
Jake M. Aquilina, Ankush Banerjee,

Gabriel N. Morais

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: 146(31), P. 22047 - 22055

Published: July 23, 2024

We describe the first total synthesis of unusual cyclopropane-containing indole alkaloid (-)-rauvomine B via a strategy centered upon intramolecular cyclopropanation tetracyclic

Language: Английский

Citations

1
Five-membered ring systems: With more than 1 N atom DOI
Larry Yet

Progress in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 211 - 257

Published: Jan. 1, 2024

Language: Английский

Citations

0
Insertion of Azavinyl Carbenes to CH/ X H Bond DOI
Yury N. Kotovshchikov, Gennadij V. Latyshev

Published: Nov. 22, 2024

The chapter represents a comprehensive review on C/ X H insertion reactions of azavinyl carbenes or carbenoids, generated from diazoimine form N 1-sulfonyl-1,2,3-triazoles. Various cascade transformations and rearrangements triggered by the initial carbene are considered. literature is classified according to type bond (CH, OH, NH, etc.) involved in reaction. last section devoted denitrogenative insertions nucleophile-tethered 5-iodotriazoles demonstrating reactivity upon annulation.

Language: Английский

Citations

0
Cluster Preface: Special Issue Honoring Masahiro Murakami’s Contributions to Science DOI Open Access
Rubén Martı́n

Synlett, Journal Year: 2023, Volume and Issue: 34(12), P. 1285 - 1288

Published: June 28, 2023

Abstract Ruben Martin (left) was born in Barcelona 1976. After receiving his PhD at the Universitat de with Prof. Antoni Riera, he moved January 2004 to Max-Planck-Institut für Kohlenforschung, Mülheim, as a Humboldt postdoctoral fellow Alois Fürstner, where worked on iron cross-coupling reactions. In May 2005, undertook further studies Massachusetts Institute of Technology Stephen L. Buchwald developed new metal-catalyzed C–C and C–N bond-forming September 2008, initiated independent career an Assistant Professor ICIQ (Tarragona). July 2013, promoted Associate subsequently ICREA Research Professor. His research interests concern discovery development synthetically useful organo­metallic methodologies. Masahiro Murakami (right) studied chemistry University ­Tokyo under supervision Mukaiyama, doctoral degree science 1984. He started assistant position Mukaiyama same place. 1987, Kyoto take late Yoshihiko Ito (1937–2006). took leave from 1991 March 1992 work for Albert Eschenmoser ETH Zürich post-doctoral fellow. then returned Kyoto, being 1993 2002. 2022, retired University. include useful, yet mechanistically interesting, organic sections, utilization photo-energy synthesis.

Language: Английский

Citations

0