Modeling hemodynamics in unruptured intracranial aneurysms under varied blood pressure conditions: An in silico study

Physics of Fluids, Год журнала: 2025, Номер 37(3)

Опубликована: Март 1, 2025

Chronic hypertension is a significant risk factor for intracranial aneurysm (IA) formation, growth, and rupture. This work aims to predict the hemodynamics in unruptured IAs investigate impact of necking bulging, along with hypotension on same. We simplified patient-specific IA geometry from literature employed two velocity profiles our three-dimensional unsteady computational fluid dynamics simulations. The blood modeled as Newtonian, vessels are non-deforming. fast Fourier transform study reveals that frequency parent artery has decreased by 40 within geometry. Velocity waveforms higher pulsatility indexes, common among young adults, pose more factors, such high wall shear stress (WSS), aggravated patients suffering aneurysms. lays groundwork improving assessment treatment planning aneurysms varying systemic pressure conditions. Hypertension increases WSS flow frequency, raising risks rupture, while promotes stagnation zones, thrombus formation. Aneurysm bulging significantly alter patterns, correlating unique vortex modes maximum WSS. developed regime map aids diagnosing treating under High indices, particularly younger individuals, amplify risks, highlighting need tailored management strategies.

Язык: Английский

Experimental and numerical analyses of the hemodynamics impact on real intracranial aneurysms: a particle tracking approach

Results in Engineering, Год журнала: 2024, Номер unknown, С. 103566 - 103566

Опубликована: Ноя. 1, 2024

Язык: Английский