Materials consideration for the design, fabrication and operation of microscale robots
Nature Reviews Materials,
Год журнала:
2024,
Номер
9(3), С. 159 - 172
Опубликована: Фев. 8, 2024
Язык: Английский
A systematic review on the potency of swarm intelligent nanorobots in the medical field
Swarm and Evolutionary Computation,
Год журнала:
2024,
Номер
86, С. 101524 - 101524
Опубликована: Фев. 29, 2024
Язык: Английский
Magnetic propelled hydrogel microrobots for actively enhancing the efficiency of lycorine hydrochloride to suppress colorectal cancer
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2024,
Номер
12
Опубликована: Фев. 21, 2024
Research
and
development
in
the
field
of
micro/nano-robots
have
made
significant
progress
past,
especially
clinical
medicine,
where
further
research
may
lead
to
many
revolutionary
achievements.
Through
experiment
microrobots,
a
controllable
drug
delivery
system
will
be
realized,
which
solve
problems
treatment.
In
this
work,
we
design
study
ability
magnetic-driven
hydrogel
microrobots
carry
Lycorine
hydrochloride
(LH)
inhibit
colorectal
cancer
(CRC)
cells.
We
successfully
designed
magnetic
driven,
biocompatible
carrying
microsphere
robot
with
Fe
3
O
4
particles
inside,
can
achieve
response,
confirmed
that
it
transport
through
fluorescence
microscope.
demonstrated
motion
mode
driven
by
rotating
external
field.
This
driving
method
allows
move
precise
manner,
providing
tremendous
potential
for
their
use
various
applications.
Finally,
selected
LH
loaded
into
microrobot
series
experiments.
significantly
inhibited
CRC
cells
proliferation
dose-
time-dependent
manner.
proliferation,
mobility
induced
apoptosis.
improve
therapeutic
effect
drugs
on
tumors.
Язык: Английский
The causal relationship between drinking water and gastrointestinal cancers: a two‐sample mendelian randomization analysis
Precision Medical Sciences,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 10, 2024
Abstract
Cancers
of
the
digestive
tract
are
a
series
diseases
that
seriously
affects
health
and
life
quality
population
worldwide,
etiology
is
closely
related
to
various
daily
habits.
Drinking
water
human
activity,
but
intrinsic
connection
between
intake
gastrointestinal
(GI)
cancers
still
unclear.
We
used
two‐sample
mendelian
randomization
(TSMR)
method
explore
potential
causal
relationship
consumption
GI
cancers.
obtained
integrated
GWAS
data
(ukb‐b‐14
898),
as
well
results
oral
cavity
cancer
(ieu‐b‐4961),
esophageal
(ebi‐a‐GCST90018841),
gastric
(ebi‐a‐GCST90018849),
liver
(ieu‐b‐4953),
hepatic
bile
duct
(ebi‐a‐GCST90018803),
pancreatic
(ebi‐a‐GCST90018893)
colorectal
(ebi‐a‐GCST90018588)
through
online
database
“IEU
OPEN
PROJECT”.
Using
inverse
variance
weighting
(IVW)
method,
weighted
median
MR
Egger
regression
simple
model
jointly
study
Mendelian
analysis
showed
negative
correlation
(weighted
media,
OR
=
0.215,
p
.021;
Egger,
0.033,
.040;
mode,
0.162,
.045),
positively
association
with
(IVW,
2.663,
.033).
There
positive
cancer,
not
statistically
significant.
The
associations
remain
uncertain.
Therefore,
Increased
amount
drinking
may
help
prevent
incidence
might
promote
development
cancer.
Язык: Английский