International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(5), С. 2184 - 2184

Опубликована: Фев. 28, 2025

Chronic obstructive pulmonary disease (COPD) is a clinical syndrome that presents as airflow limitation with poor reversibility accompanied by dynamic hyperinflation of the lung. It complex chronic inflammatory airway changes caused exposure to noxious particles or gases, such cigarette smoke. The involves persistent inflammation and oxidative stress, perpetuated frequent exacerbations. prevalence COPD on rise, prediction it will be leading cause morbidity mortality over next decade. Despite global burden its associated mortality, treatment remains limited. Although understanding pathogenesis has increased last two decades, molecular approaches develop new therapies for have lagged. Here, we review potential developing novel COPD.

Язык: Английский