GMOs or non-GMOs? The CRISPR Conundrum DOI Creative Commons
Aftab Ahmad, Amer Jamil, Nayla Munawar

и другие.

Frontiers in Plant Science, Год журнала: 2023, Номер 14

Опубликована: Окт. 9, 2023

CRISPR-Cas9, the “genetic scissors”, is being presaged as a revolutionary technology, having tremendous potential to create designer crops by introducing precise and targeted modifications in genome achieve global food security face of climate change increasing population. Traditional genetic engineering relies on random unpredictable insertion isolated genes or foreign DNA elements into plant genome. However, CRISPR-Cas based gene editing does not necessarily involve inserting element from different species but new traits precisely altering existing genes. CRISPR edited are touching markets, however, world community divided over whether these should be considered genetically modified (GM) non-GM. Classification crops, especially transgene free traditional GM will significantly affect their future public acceptance some regions. Therefore, depending upon regulation non-GMs, perception. Here we briefly discuss how crops. In addition, reagents delivery tools produce transgene-free Moreover, also summarize regulatory classification countries regulating We that controversy CRISPR-edited plants non-GM continue until universal, transparent, scalable framework for introduced worldwide, with increased awareness involving all stakeholders.

Язык: Английский

Microalgae biofuels: illuminating the path to a sustainable future amidst challenges and opportunities DOI Creative Commons
Min Wang, Xiaoxue Ye,

Hongwen Bi

и другие.

Biotechnology for Biofuels and Bioproducts, Год журнала: 2024, Номер 17(1)

Опубликована: Янв. 23, 2024

Abstract The development of microalgal biofuels is significant importance in advancing the energy transition, alleviating food pressure, preserving natural environment, and addressing climate change. Numerous countries regions across globe have conducted extensive research strategic planning on bioenergy, investing funds manpower into this field. However, microalgae biofuel industry has faced a downturn due to constraints high costs. In past decade, with new strains, technologies, equipment, feasibility large-scale production should be re-evaluated. Here, we gathered results from decade regarding production, providing insights opportunities challenges by perspectives selection, modification, cultivation. review, suggest that highly adaptable are preferred choice for especially strains can utilize concentrations inorganic carbon sources possess stress resistance. use omics technologies genetic editing greatly enhanced lipid accumulation microalgae. associated risks constrained outdoor Therefore, relatively controllable cultivation method photobioreactors (PBRs) made it mainstream approach production. Moreover, adjusting performance parameters PBRs also enhance future, given relentless escalation demand sustainable sources, deemed pivotal constituent national planning, particularly case China. advancement synthetic biology helps reduce genetically modified (GM) enhances economic viability their Graphical

Язык: Английский

Процитировано

46

Genome editing of crops: A renewed opportunity for food security DOI Creative Commons

Fawzy Georges,

Heather Ray

GM crops & food, Год журнала: 2017, Номер 8(1), С. 1 - 12

Опубликована: Янв. 2, 2017

Genome editing of crop plants is a rapidly advancing technology whereby targeted mutations can be introduced into plant genome in highly specific manner and with great precision. For the most part, does not incorporate transgenic modifications far superior to conventional chemical mutagenesis. In this study we bring focus some underlying differences between 3 existing technologies: classical breeding, genetic modification editing. We discuss main achievements from each area highlight their common characteristics individual limitations, while emphasizing unique capabilities subsequently examine possible regulatory mechanisms which governments may inclined use assessing status edited products. If assessed on basis phenotype rather than process by they are obtained, these products will categorized as equivalent those produced This would mean that subject restrictions imposed genetically modified products, except cases where mutation involves large sequence insertion genome. conclude examining potential societal acceptance technology, reinforced scientific perspective promoting such acceptance.

Язык: Английский

Процитировано

161

Iron biofortification in the 21st century: setting realistic targets, overcoming obstacles, and new strategies for healthy nutrition DOI Creative Commons
Marta W. Vasconcelos, Wilhelm Gruissem, Navreet K. Bhullar

и другие.

Current Opinion in Biotechnology, Год журнала: 2016, Номер 44, С. 8 - 15

Опубликована: Окт. 22, 2016

Язык: Английский

Процитировано

123

A comparison of the EU regulatory approach to directed mutagenesis with that of other jurisdictions, consequences for international trade and potential steps forward DOI Open Access
Dennis Eriksson,

Drew L. Kershen,

Alexandre Lima Nepomuceno

и другие.

New Phytologist, Год журнала: 2018, Номер 222(4), С. 1673 - 1684

Опубликована: Дек. 13, 2018

Summary A special regulatory regime applies to products of recombinant nucleic acid modifications. ruling from the European Court Justice has interpreted this in a way that it also emerging mutagenesis techniques. Elsewhere progress is ongoing. In 2015, Argentina launched framework, followed by Chile 2017 and recently Brazil Colombia. March 2018, USDA announced will not regulate genome‐edited plants differently if they could have been developed through traditional breeding. Canada an altogether different approach with their Plants Novel Traits regulations. Australia currently reviewing its Gene Technology Act. This article illustrates deviation Union's (EU's) one most other countries studied here. Whereas EU does implement case‐by‐case approach, taken several jurisdictions. Also, court adheres process‐based while stronger emphasis on regulation resulting product. It concluded that, unless functioning identity preservation system for directed can be established, results risk asynchronous approvals disruptions international trade.

Язык: Английский

Процитировано

111

New directions for integrated weed management: Modern technologies, tools and knowledge discovery DOI
Nicholas E. Korres, Nilda R. Burgos, Ilias Travlos

и другие.

Advances in agronomy, Год журнала: 2019, Номер unknown, С. 243 - 319

Опубликована: Янв. 1, 2019

Язык: Английский

Процитировано

97

Unraveling Field Crops Sensitivity to Heat Stress: Mechanisms, Approaches, and Future Prospects DOI Creative Commons
Muhammad Azhar Nadeem, Jiajia Li, Minghua Wang

и другие.

Agronomy, Год журнала: 2018, Номер 8(7), С. 128 - 128

Опубликована: Июль 23, 2018

The astonishing increase in temperature presents an alarming threat to crop production worldwide. As evident by huge yield decline various crops, the escalating drastic impacts of heat stress (HS) are putting global food as well nutritional security at high risk. HS is a major abiotic that influences plant morphology, physiology, reproduction, and productivity physiological molecular responses dynamic research areas, techniques being adopted for producing tolerant plants. In this article, we reviewed recent findings, impacts, adoption, tolerance cellular, organellar, whole level reported several approaches used improve Omics unravel mechanisms underlying thermotolerance, which imperative understand processes toward HS. Our review about may enlighten ways develop thermo-tolerant cultivars produce plants agriculturally important adverse climatic conditions.

Язык: Английский

Процитировано

93

Genome editing using CRISPR/Cas9–targeted mutagenesis: An opportunity for yield improvements of crop plants grown under environmental stresses DOI

Mostafa Abdelrahman,

Abdullah M. Al‐Sadi, Alireza Pour‐Aboughadareh

и другие.

Plant Physiology and Biochemistry, Год журнала: 2018, Номер 131, С. 31 - 36

Опубликована: Март 12, 2018

Язык: Английский

Процитировано

85

Benefits of genome-edited crops: expert opinion DOI Creative Commons
Rim Lassoued, Diego Maximiliano Macall, Hayley Hesseln

и другие.

Transgenic Research, Год журнала: 2019, Номер 28(2), С. 247 - 256

Опубликована: Март 4, 2019

Innovation in agriculture is pervasive. However, spite of the success stories twentieth century plant breeding, twenty-first has ushered a set challenges that solutions from past are unlikely to address. sustained research and amalgamation number disciplines resulted new breeding techniques (NBTs), such as genome editing, which offer promise opportunities resolve some issues. Here we present results an expert survey on added potential benefits genome-edited crops compared those developed through genetic modification (GM) conventional breeding. Overall, reveal consensus among experts enhanced agronomic performance product quality over alternatives. The majority indicated regulations for health safety, followed by export markets, consumers, media play major role determining where how NBTs, including will be used agriculture. Further needed gauge opinion after Court Justice European Union ruling establishing site-specific mutagenic technologies regulated same fashion GM crops, regardless whether foreign DNA final variety.

Язык: Английский

Процитировано

85

Generation of a new thermo-sensitive genic male sterile rice line by targeted mutagenesis of TMS5 gene through CRISPR/Cas9 system DOI Creative Commons
Hirendra Nath Barman, Zhonghua Sheng, Sajid Fiaz

и другие.

BMC Plant Biology, Год журнала: 2019, Номер 19(1)

Опубликована: Март 20, 2019

Two-line hybrid rice with high yield potential is increasingly popular and the photo- temperature-sensitive male sterile line one of basic components for two-line breeding. The development lines through conventional breeding a lengthy laborious process, whereas developing thermo-sensitive genic (TGMS) by editing temperature-sensitivity gene CRISPR/Cas9 efficient convenient. Here, sterility was induced employing technology to modify TMS5. Two TGMS mutants, tms5–1 tms5–2, both lacking any residual T-DNA, were generated in indica cultivar Zhongjiazao17 (cv. YK17) background. When grown at sub-optimal temperature (22 °C), mutants produced viable pollen successfully grain self-fertilization, but temperatures 24 26 °C, their no set. F1 hybrids derived from crosses between YK17S (tms5–1) three different restorer outperformed parental respect related traits. system proved be new superior can widely utilized rice.

Язык: Английский

Процитировано

81

Breeding custom‐designed crops for improved drought adaptation DOI Creative Commons
Rajeev K. Varshney, Rutwik Barmukh, Manish Roorkiwal

и другие.

Advanced Genetics, Год журнала: 2021, Номер 2(3)

Опубликована: Сен. 1, 2021

Abstract The current pace of crop improvement is inadequate to feed the burgeoning human population by 2050. Higher, more stable, and sustainable production required against a backdrop drought stress, which causes significant losses in yields. Tailoring crops for adaptation may hold key address these challenges provide resilient systems future harvests. Understanding genetic molecular landscape functionality alleles associated with adaptive traits will make designer breeding prospective approach improvement. Here, we highlight potential genomics technologies combined physiology high‐throughput identification architecture drought‐adaptive explore innovative genomic strategies designing crops.

Язык: Английский

Процитировано

74