Journal of Geriatric Oncology, Год журнала: 2024, Номер 15(5), С. 101760 - 101760
Опубликована: Март 30, 2024
Язык: Английский
Journal of Geriatric Oncology, Год журнала: 2024, Номер 15(5), С. 101760 - 101760
Опубликована: Март 30, 2024
Язык: Английский
Current Hypertension Reports, Год журнала: 2024, Номер 26(5), С. 225 - 236
Опубликована: Фев. 2, 2024
To summarise the evidence regarding which patients might benefit from deprescribing antihypertensive medications. Older with frailty, multi-morbidity and subsequent polypharmacy are at higher risk of adverse events treatment, therefore may deprescribing. It is possible to examine an individual's these events, use this identify those people where benefits treatment be outweighed by harms. While such considered for deprescribing, long-term effects strategy remain unclear. Evidence now exists support identification who treatment. These could targeted interventions, although harms approach Randomised controlled trials still needed in high-risk frailty multi-morbidity.
Язык: Английский
Процитировано
4Journal of the American Medical Directors Association, Год журнала: 2024, Номер 25(9), С. 105122 - 105122
Опубликована: Июнь 28, 2024
Язык: Английский
Процитировано
4Current Opinion in Supportive and Palliative Care, Год журнала: 2025, Номер 19(1), С. 2 - 11
Опубликована: Янв. 30, 2025
This review raises awareness regarding the lack of data available for healthcare professionals caring older adults with cancer when using supportive care medications. Guidelines concrete recommendations on appropriate use medications in cancer. Some guidelines, such as National Comprehensive Cancer Network Older Adult Oncology guideline, contain vital information prescribers to consider choosing a medication. Information at present most guidelines is generally vague, identifying areas where caution required adults, without specific details. Research needed assess efficacy and safety adults.
Язык: Английский
Процитировано
0Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Age and Ageing, Год журнала: 2025, Номер 54(2)
Опубликована: Фев. 1, 2025
Abstract Objective To validate STOPPCog, a list of explicit criteria for potentially inappropriate medication use in cognitively vulnerable older adults. Design A Delphi consensus survey an expert panel comprising academic geriatricians, old age psychiatrists, general practitioners, and clinical pharmacists. Setting Ireland. Subjects Nine panellists. Methods STOPPCog were initially created by the authors based on experience literature appraisal. Criteria organised according to drug/drug class. Using methodology, panellists ranked their agreement with each criterion 5-point Likert scale provided written feedback. median value 1 or 2 (strongly agree/agree) 25th centile ≤2 included final list. Results All completed two validation rounds. Twenty-five proposed initially, twenty accepted. One was rejected (multi-vitamin supplements), four rephrased (two these combined one greater clarity). The comprised 23 that are arranged six subgroups i.e. (i) drugs anticholinergic properties taken daily; (ii) sedative (iii) may exacerbate psychotic symptoms patients alpha-synuclein pathology; (iv) used chronic pain; (v) without proven efficacy dementia (vi) no benefit advanced stage rating 3.0 where palliation be appropriate. Conclusion comprises relating medications assist physicians deprescribing this patient population.
Язык: Английский
Процитировано
0Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Journal of Palliative Medicine, Год журнала: 2025, Номер unknown
Опубликована: Март 20, 2025
Background: Palliative care (PC) patients are at high risk of polypharmacy, thereby imposing a substantial burden on patients, including increased pill burden, adverse drug events, and falls. PC pharmacists play critical role in deprescribing aligning medications with goals for this population, but few studies demonstrate opportunities.
Язык: Английский
Процитировано
0Drugs & Aging, Год журнала: 2025, Номер unknown
Опубликована: Март 20, 2025
Язык: Английский
Процитировано
0JAMA Internal Medicine, Год журнала: 2025, Номер unknown
Опубликована: Март 24, 2025
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast JAMA+ AI Journals Network Open Cardiology Dermatology Health Forum Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) JN Learning / CMESubscribeJobsInstitutions LibrariansReprints Permissions Terms Use Privacy Accessibility Statement 2025 American Medical Association. All Rights Reserved Search Archive Input Term Sign In Individual inCreate an Account Access through institution Purchase Options: Buy this article Rent Subscribe the journal
Язык: Английский
Процитировано
0Journal of Pain and Symptom Management, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Polypharmacy and inappropriate prescribing are prevalent among end-of-life cancer patients, potentially compromising symptom management quality of life. Limited data available on medications (PIMs) omissions (PPOs) opioid in South Korea, particularly home-based hospice care settings. This study aimed to evaluate the prevalence PIMs PPOs advanced patients referred identify factors associated with these issues. A retrospective observational included 102 a single center's between November 2022 2023. were assessed using STOPPFrail criteria, while defined as inadequate for moderate severe pain. Logistic regression analysis identified PPOs. observed 40.2% higher those over 70 years old (48.7%) multiple comorbidities. Statins (25.5%) antihypertensives (29.4%) most common PIMs. Among pain, 45.5% experienced due prescriptions. Older age (OR 3.90, p < 0.01) comorbidities 20.90, significantly PIMs, diabetes was linked 2.00, = 0.01). The findings highlight critical gaps medication patients. Systematic deprescribing protocols improved strategies address stigma hesitancy essential align treatments goals enhance patient
Язык: Английский
Процитировано
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