Best Practice & Research Clinical Rheumatology, Год журнала: 2022, Номер 36(4), С. 101794 - 101794
Опубликована: Ноя. 8, 2022
Язык: Английский
BMJ, Год журнала: 2022, Номер unknown, С. e072117 - e072117
Опубликована: Сен. 22, 2022
Ziauddeen N, Gurdasani D, O’Hara ME, et al. Characteristics of long covid: findings from a social media survey.medRxiv2021 [Preprint] doi:10.1136/jech-2021-SSMabstracts.194.
Язык: Английский
Процитировано
132
The Lancet, Год журнала: 2024, Номер 404(10453), С. 707 - 724
Опубликована: Июль 31, 2024
Язык: Английский
Процитировано
103
Journal of Neurology, Год журнала: 2022, Номер 269(8), С. 3990 - 3999
Опубликована: Апрель 30, 2022
Fatigue in its many forms of physical, mental, and psychosocial exhaustion is a common symptom post-COVID-19 condition, also known as "Long COVID." Persistent fatigue COVID-19 patients frequently accompanied by cognitive dysfunction neuropsychiatric symptoms; however, less about the relationships between these components condition itself. Consequently, present study sought to (1) distinguish types experienced participants, (2) investigate whether deficits across various domains conditions predicted different fatigue. The included 136 referred for neuropsychological evaluation due complaints 8 months on average after SARS-CoV-2 infection. Measures self-reported (physical, cognitive, psychosocial), questionnaires (assessing symptoms depression, anxiety, apathy, executive functioning), comprehensive assessment, quality life everyday functioning. Results showed that reports clinical significant were pervasive our sample (82.3% participants), with physical rated highest relative subscale maximum. Elevated levels measures along attentional difficulties tests found be consistently important predictors among This implicates both stresses importance holistic approach assessing considering potential treatment experiencing
Язык: Английский
Процитировано
96
Psychiatry and Clinical Neurosciences, Год журнала: 2022, Номер 77(2), С. 84 - 93
Опубликована: Ноя. 17, 2022
Although some patients have persistent symptoms or develop new following coronavirus disease 2019 (COVID-19) infection, neuropsychiatric aspects of long COVID are not well known. This review summarizes and provides an update on the dimensions COVID. Its manifestations commonly include fatigue, cognitive impairment, sleep disorders, depression, anxiety, post-traumatic stress disorder. There no specific tests for COVID, but characteristic findings such as hypometabolism positron emission tomography been reported. The possible mechanisms inflammation, ischemic effects, direct viral invasion, social environmental changes. Some patient characteristics severity complications acute COVID-19 infection may be associated with increased risk symptoms. Long resolve spontaneously persist, depending type established treatments lacking, various psychological pharmacological attempted. Vaccination against plays a key role in prevention disease. With differences among SARS-CoV-2 variants, including omicron variant, likely to change future. Further studies clarifying effective warranted.
Язык: Английский
Процитировано
89
Journal of Affective Disorders, Год журнала: 2022, Номер 324, С. 162 - 169
Опубликована: Дек. 28, 2022
A considerable proportion of people experience lingering symptoms after Coronavirus Disease 2019 (COVID-19). The aim this study was to investigate the frequency, pattern and functional implications cognitive impairments in patients at a long-COVID clinic who were referred hospitalisation with COVID-19 or by their general practitioner.Patients underwent screening completed questionnaires regarding subjective cognition, work function quality life. Patients' performance compared that 150 age-, sex-, education-matched healthy controls (HC) individually expected calculated based on age, sex education.In total, 194 assessed, average 7 months (standard deviation: 4) acute COVID-19.44-53 % displayed clinically relevant HC performance, respectively. Moderate large seen global cognition working memory executive function, while mild moderate occurred verbal fluency, learning memory. Hospitalised (n = 91) non-hospitalised 103) showed similar degree analyses adjusted for age time since illness. Patients cognitively impaired group older, more often hospitalised, had higher BMI frequent asthma, female. More objective impairment associated difficulties, poorer lower life.The cross-sectional, which precludes causality inferences.These findings underscore need assess treat clinics.
Язык: Английский
Процитировано
52
Psychiatry Research, Год журнала: 2022, Номер 319, С. 115006 - 115006
Опубликована: Дек. 10, 2022
Язык: Английский
Процитировано
51
Journal of Internal Medicine, Год журнала: 2023, Номер 294(5), С. 563 - 581
Опубликована: Сен. 27, 2023
Abstract The long‐term effects of COVID‐19 on cognitive function have become an area increasing concern. This paper provides overview characteristics, risk factors, possible mechanisms, and management strategies for dysfunction in post‐COVID‐19 condition (PCC). Prolonged is one the most common impairments PCC, affecting between 17% 28% individuals more than 12 weeks after infection persisting some cases several years. Cognitive dysfunctions can be manifested as a wide range symptoms including memory impairment, attention deficit, executive dysfunction, reduced processing speed. Risk factors developing with or without impairments, include advanced age, preexisting medical conditions, severity acute illness. underlying mechanisms remain unclear, but proposed contributors neuroinflammation, hypoxia, vascular damage, latent virus reactivation not excluding possibility direct viral invasion central nervous system, illustrating complex pathology. As individual variation large, neuropsychological examination person‐centered multidimensional approach are required. According to World Health Organization, limited evidence COVID‐19‐related necessitates implementing rehabilitation interventions from established practices similar conditions. Psychoeducation compensatory skills training recommended. Assistive products environmental modifications adapted needs might helpful. In specific attention‐ working dysfunctions, training—carefully monitored intensity—might effective people who do suffer post‐exertional malaise. Further research crucial evidence‐based impairments.
Язык: Английский
Процитировано
41
General Hospital Psychiatry, Год журнала: 2022, Номер 78, С. 80 - 86
Опубликована: Июль 31, 2022
Язык: Английский
Процитировано
40
Brain Behavior & Immunity - Health, Год журнала: 2023, Номер 27, С. 100587 - 100587
Опубликована: Янв. 5, 2023
Subjective and objective cognitive dysfunction are reported after COVID-19 but with limited data on their congruence associations the severity of acute disease. The aim this cohort study is to describe prevalence subjective at three six months symptoms psychological disease-related factors.We assessed a 184 patients COVID-19: 82 admitted Intensive Care Unit (ICU), 53 regular hospital wards, 49 isolated home. A non-COVID control group individuals was included. Demographic clinical were collected. symptoms, impairment, depressive post-traumatic stress disorder (PTSD) assessed.At months, impairment by 32.3% ICU-treated, 37.3% ward-treated, 33.3% home-isolated observed in 36.1% 34.7% 8.9% patients. associated PTSD female sex, not assessment or metrics.One-third patients, regardless disease severity, high levels which results from screening demographic factors. Our stresses importance thorough reporting long-term for underlying mental health related factors such as depression.
Язык: Английский
Процитировано
39
Scientific Reports, Год журнала: 2023, Номер 13(1)
Опубликована: Апрель 19, 2023
In this study, we aimed to examine different cognitive domains in a large sample of patients with post COVID-19 syndrome. Two hundred and fourteen patients, 85.04% women, ranged 26 64 years (mean = 47.48 years) took part investigation. Patients' processing speed, attention, executive functions various language modalities were examined online using comprehensive task protocol designed for research. Alteration some the tasks was observed 85% participants, being attention tests ones that show highest percentage severe impairment. Positive correlations between age participants almost all assessed, implying better performance milder impairment increasing age. comparisons according age, oldest found maintain their relatively preserved, only mild speed processing, while youngest showed most marked heterogeneous These results confirm subjective complaints syndrome and, thanks size, allow us observe effect patient on performance, an never reported before these characteristics.
Язык: Английский
Процитировано
31