Cogent Food & Agriculture,
Год журнала:
2023,
Номер
9(1)
Опубликована: Июль 4, 2023
The
fruits
of
citrus
family
are
rich
in
flavonoids
with
superior
antioxidant
properties;
bioactive
components
potentially
beneficial
without
adverse
effects
or
cytotoxicity
healthy
individuals.
Citrus
fruit
peel
contains
ample
amount
hesperidin
which
is
flavanone
glycoside
and
has
showed
effective
role
biological
systems
as
an
anti-inflammatory
compound.
Different
studies
have
investigated
such
roles
hesperidin.
Due
to
potential
its
derivatives,
these
compounds
been
intensively
studied
for
their
anti-cancer
cardio
protective
perspective.
This
review
article
a
collection
updated
data
covering
different
aspects
like
occurrence,
physical
chemical
composition,
pharmacokinetics
safety
compounds.
Moreover,
against
lifestyle-related
metabolic
syndromes
mechanistic
perspective
also
extensively
discussed
this
article.
Molecules,
Год журнала:
2023,
Номер
28(7), С. 2965 - 2965
Опубликована: Март 26, 2023
Lime
peels
are
food
waste
from
lime
product
manufacturing.
We
previously
developed
and
optimized
a
green
extraction
method
for
hesperidin-limonin-rich
peel
extract.
This
study
aimed
to
identify
the
metabolomics
profile
of
phytochemicals
anti-cancer
effects
ethanolic
extract
(Citrus
aurantifolia)
against
liver
cancer
cells
PLC/PRF/5.
The
extract's
was
analyzed
by
using
LC-qTOF/MS
GC-HRMS.
were
studied
MTT
assay,
Annexin-PI
Transwell-invasion
assay.
Results
show
that
average
IC50(s)
hesperidin,
limonin,
on
cells'
viability
165.615,
188.073,
503.004
µg/mL,
respectively.
At
IC50
levels,
induced
more
apoptosis
than
those
pure
compounds
when
incubating
24
48
h
(p
<
0.0001).
A
combination
limonin
hesperidin
showed
synergistic
effect
induction
0.001),
but
still
less
at
h.
Furthermore,
significantly
inhibited
cell
invasion
better
equal
hesperidin.
level,
contains
many
folds
lower
amounts
doses
compounds.
Besides
there
another
60
22
detected
LCMS
GCMS
analyses,
Taken
altogether,
superior
compared
compound
likely
results
combinatorial
other
phytochemical
components
in
Foods,
Год журнала:
2025,
Номер
14(5), С. 814 - 814
Опубликована: Фев. 27, 2025
This
study
aimed
to
evaluate
the
potential
of
beetroot
powder
(BP)
as
a
functional
ingredient
in
biscuits
by
investigating
its
effects
on
nutritional
composition,
sensory
properties,
and
glycemic
response.
The
primary
goal
was
determine
whether
BP
could
serve
natural
alternative
synthetic
additives
while
maintaining
product
stability
consumer
acceptability.
Biscuits
were
formulated
replacing
spelt
flour
with
15,
20,
25%
BP.
impact
assessed
based
betaine
content,
macro-
microelements,
index
(GI),
acrylamide
concentration.
Thermal
analysis
(DSC
TGA)
water
activity
measurements
confirmed
BP's
during
six
months
storage.
Increased
content
led
higher
levels
mineral
enrichment,
particularly
potassium
phosphorus
among
macroelements
zinc
microelements.
Sensory
identified
20%
most
preferred,
acceptable
ratings
even
after
months.
Hardness
initially
increased
incorporation
but
decreased
over
time
(p
<
0.05).
BP-enriched
significantly
lower
than
control
samples
well
below
reference
safety
threshold.
Notably,
consuming
did
not
trigger
sharp
postprandial
glucose
spike,
GI
sample
(20%
BP)
measured
at
49
±
11.
These
findings
confirm
that
improves
characteristics
ensuring
stability,
supporting
application
confectionery
products.
Pharmaceutics,
Год журнала:
2021,
Номер
13(11), С. 1818 - 1818
Опубликована: Окт. 31, 2021
Citrus
fruits
and
juices
have
been
studied
extensively
for
their
potential
involvement
in
the
prevention
of
various
diseases.
Flavanones,
characteristic
polyphenols
citrus
species,
are
primarily
compounds
responsible
these
health
benefits.
Using
silico
vitro
methods,
we
exploring
possible
antidiabetic
action
narirutin,
a
flavanone
family
member.
The
goal
research
was
to
anticipate
how
narirutin
would
interact
with
eight
distinct
receptors
implicated
diabetes
control
complications,
namely,
dipeptidyl-peptidase
4
(DPP4),
protein
tyrosine
phosphatase
1B
(PTP1B),
free
fatty
acid
receptor
1
(FFAR1),
aldose
reductase
(AldR),
glycogen
phosphorylase
(GP),
alpha-amylase
(AAM),
peroxisome
proliferator-activated
gamma
(PPAR-γ),
alpha-glucosidase
(AGL),
while
study
looked
into
narirutin's
inhibitory
impact
on
alpha-glucosidase.
results
indicate
that
interacted
remarkably
most
had
an
excellent
activity
during
tests
suggesting
its
potent
role
among
different
constituent
management
also
complications.
Cogent Food & Agriculture,
Год журнала:
2023,
Номер
9(1)
Опубликована: Июль 4, 2023
The
fruits
of
citrus
family
are
rich
in
flavonoids
with
superior
antioxidant
properties;
bioactive
components
potentially
beneficial
without
adverse
effects
or
cytotoxicity
healthy
individuals.
Citrus
fruit
peel
contains
ample
amount
hesperidin
which
is
flavanone
glycoside
and
has
showed
effective
role
biological
systems
as
an
anti-inflammatory
compound.
Different
studies
have
investigated
such
roles
hesperidin.
Due
to
potential
its
derivatives,
these
compounds
been
intensively
studied
for
their
anti-cancer
cardio
protective
perspective.
This
review
article
a
collection
updated
data
covering
different
aspects
like
occurrence,
physical
chemical
composition,
pharmacokinetics
safety
compounds.
Moreover,
against
lifestyle-related
metabolic
syndromes
mechanistic
perspective
also
extensively
discussed
this
article.
