Annals of Civil and Environmental Engineering,
Год журнала:
2024,
Номер
8(1), С. 076 - 086
Опубликована: Сен. 13, 2024
A
significant
obstacle
to
agricultural
productivity
that
jeopardizes
the
availability
of
food
is
crop
diseases
and
farmer
livelihoods
by
reducing
yields.
Traditional
visual
assessment
methods
for
disease
diagnosis
are
effective
but
complex,
often
requiring
expert
observers.
Recent
advancements
in
deep
learning
indicate
potential
increasing
accuracy
automating
identification.
Developing
accessible
diagnostic
tools,
such
as
web
applications
leveraging
CNNs,
can
provide
farmers
with
efficient
accurate
identification,
especially
regions
limited
access
advanced
technologies.
The
main
goal
develop
a
productive
system
recognize
tomato
plant
diseases.
model
was
trained
on
collection
images
healthy
damaged
leaves
from
PlantVillage
using
transfer
techniques.
dataset
were
cleansed
resizing
them
256
×
224
match
dimensions
used
pre-trained
models
min-max
normalization.
An
evaluation
VGG16,
VGG19,
DenseNet121
based
performance
loss
value
7
categories
tomatoes
guided
selection
most
practical
application.
VGG16
achieved
84.54%
accuracy,
VGG19
84.62%,
98.28%,
making
chosen
due
its
highest
accuracy.
application
development
architecture
integrated
Django
framework,
which
built
Python.
This
enables
real-time
uploaded
leaves.
proposed
allows
early
detection
diseases,
helping
mitigate
losses.
supports
sustainable
farming
practices
increases
productivity.
Heliyon,
Год журнала:
2024,
Номер
10(3), С. e25261 - e25261
Опубликована: Янв. 29, 2024
Due
to
its
nutritional
and
bioactive
content,
tomato
pomace
(TP)
remains
among
the
world's
richest
fruits
vegetables.
Tomatoes
TP
(generated
coproduct)
are
a
very
rich
source
of
lycopene
other
carotenoid
compounds
contain
an
essential
amount
polyphenols,
policosanol,
phytosterols,
organic
acids,
dietary
fibers,
minerals,
vitamins.
is
promising
significant
with
antioxidant
antimicrobial
potential.
Therefore,
their
consumption
known
be
effective
in
preventing
certain
chronic
diseases.
For
example,
prevents
prostate
cancer
acts
as
hepatoprotector
genoprotector
against
mycotoxins,
pesticide
residues,
heavy
metals.
Thus,
valorization
food
ingredient
can
great
health,
economic
environmental
interest
contribute
improving
nutrition
security.
During
last
decades,
considerable
efforts
have
been
made
valorize
crucial
functional
improving:
(i)
properties,
(ii)
sensory
characteristics
(iii)
shelf
life
many
foods.
The
current
review
aims
update
summarize
knowledge
on
recent
applications
TP,
particularly
use
improve
properties
The EPMA Journal,
Год журнала:
2022,
Номер
13(3), С. 461 - 486
Опубликована: Июль 8, 2022
Abstract
According
to
the
GLOBOCAN
2020,
prostate
cancer
(PCa)
is
most
often
diagnosed
male
in
112
countries
and
leading
cancer-related
death
48
countries.
Moreover,
PCa
incidence
permanently
increases
adolescents
young
adults.
Also,
rates
of
metastasising
continuously
grow
up
populations.
Corresponding
socio-economic
burden
enormous:
treatment
costs
increase
more
rapidly
than
for
any
other
cancer.
In
order
reverse
current
trends
exploding
cases
costs,
pragmatic
decisions
should
be
made,
favour
advanced
populational
screening
programmes
effective
anti-PCa
protection
at
level
health-to-disease
transition
(sub-optimal
health
conditions)
demonstrating
highest
cost-efficacy
treatments.
For
doing
this,
paradigm
change
from
reactive
treatments
clinically
manifested
predictive
approach
personalised
prevention
essential.
Phytochemicals
are
associated
with
potent
anti-cancer
activity
targeting
each
stage
carcinogenesis
including
cell
apoptosis
proliferation,
invasiveness
metastatic
disease.
example,
their
positive
effects
demonstrated
stabilising
restoring
mitochondrial
quality,
which
if
compromised
strongly
sub-optimal
conditions
strong
predisposition
aggressive
sub-types.
Further,
phytochemicals
significantly
enhance
response
cells
therapies
radio-
chemotherapy.
Evident
plant-based
mitigation
negative
side-effects
frequently
observed
conventional
has
been
reported.
Finally,
dual
anti-viral
such
as
these
silibinin
have
being
highly
relevant
improved
management
secondary
tertiary
care,
under
pandemic
conditions,
since
PCa-affected
individuals
per
evidence
vulnerable
towards
COVID-19
infection.
Here,
we
present
a
comprehensive
data
analysis
considered
primary
care
well
an
disease
framework
predictive,
preventive
medicine.
Journal of Exploratory Research in Pharmacology,
Год журнала:
2024,
Номер
9(1), С. 51 - 64
Опубликована: Фев. 6, 2024
Cancer
is
a
significant
global
health
issue
and
primary
cause
of
death.
Extensive
research
has
led
to
the
development
various
anticancer
medications,
driven
by
an
improved
knowledge
comprehension
molecular
pathways
involved
in
cancer
growth.
However,
there
need
for
new
approaches
enhance
effectiveness
existing
therapies.
Dietary
phytochemicals
have
gained
increasing
attention
due
their
potential
role
tumor
prevention.
These
bioactive
compounds
derived
from
plants
exhibit
wide
range
beneficial
effects
on
human
health,
including
ability
inhibit
carcinogenesis
promote
activities.
Examples
dietary
with
promising
properties
include
vitamin
D,
E,
lycopene,
fisetin,
genistein,
epigallocatechin
gallate,
crocetin,
curcumin,
cyanidins,
gingerol.
often
exert
regulating
interconnected
associated
progression.
Some
these
apoptosis
pathway,
cyclooxygenase-2
ATP-dependent
chromatin
remodeling
DNA
methylation-epigenetic
Hedgehog
signaling
signal
transducer
activator
transcription
protein-3
angiogenesis
inhibition
Wnt
pathway.
This
comprehensive
review
aims
summarize
current
prevention,
highlighting
mechanisms
action
therapeutic
applications.
Journal of Food Process Engineering,
Год журнала:
2025,
Номер
48(2)
Опубликована: Фев. 1, 2025
ABSTRACT
The
current
study
performed
drying
of
tomato
slices
in
a
atmosphere
with
hydrogen
gas
(RAD
MIX
;
gaseous
mixture
4%
hydrogen,
5%
carbon
dioxide
and
91%
nitrogen),
compared
100%
air,
nitrogen
environments.
All
the
experiments
were
carried
out
at
60°C.
Control
samples
pretreated
1%
Potassium
metabisulfite
(KMS)
treated
dried
to
final
moisture
content
around
13.29%
13.70%
(wet
basis),
respectively.
behavior
quality
characteristics
including
color
change
(Δ
E
),
lycopene
retention,
total
phenolics
rehydration
ratio
products
studied.
better
retention
was
observed
sulfite
RAD
sample.
)
found
be
10.1,
by
94.28%
(3.3
mg/100
g),
maximum
4.67
subjected
reduced
atmospheric
drying.
Additionally,
lesser
for
KMS
than
control
samples.
It
that
use
concentration
environment
significantly
impacted
parameters
slices.
pretreatment
advantageous
technique
terms
diffusivity,
antioxidant
compounds
Pharmaceuticals,
Год журнала:
2025,
Номер
18(3), С. 403 - 403
Опубликована: Март 13, 2025
Background:
Carotenoids
are
bioactive
tetraterpenoid
C40
pigments
that
actively
synthesized
by
plants,
bacteria,
and
fungi.
Compounds
such
as
α-carotene,
β-carotene,
lycopene,
lutein,
astaxanthin,
β-cryptoxanthin,
fucoxanthin,
zeaxanthin
have
attracted
increasing
attention
for
their
antiaging
properties.
They
exhibit
antioxidant,
neuroprotective,
anti-inflammatory
properties,
contributing
to
the
prevention
treatment
of
age-related
diseases.
Objectives:
The
aim
this
study
was
comprehensively
analyze
pharmacological
potential
biological
mechanisms
carotenoids
associated
with
disorders
evaluate
application
in
nutraceuticals,
pharmaceuticals,
cosmeceuticals.
Methods:
A
systematic
review
studies
published
over
past
two
decades
conducted
using
databases
PubMed,
Scopus,
Web
Science.
selection
criteria
included
clinical,
silico,
vivo,
vitro
investigating
therapeutic
effects
carotenoids.
Results:
demonstrate
a
variety
health
benefits,
including
macular
degeneration,
cancer,
cognitive
decline,
metabolic
disorders,
skin
aging.
Their
role
nutraceuticals
is
well
supported
ability
modulate
oxidative
stress
inflammatory
pathways.
In
show
promising
results
formulations
targeting
neurodegenerative
diseases
disorders.
cosmeceuticals,
they
improve
protecting
it
against
UV
radiation
damage.
However,
bioavailability,
optimal
dosages,
toxicity,
interactions
other
compounds
remain
critical
factors
maximize
efficacy
still
require
careful
evaluation
scientists.
Conclusions:
interventions
applications
fields.
Further
research
needed
optimize
formulas,
confirm
long-term
safety
effectiveness,
especially
aging
population.
Current Oncology Reports,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 18, 2025
Abstract
Purpose
of
Review
Prostate
cancer
(PCa)
is
the
most
prevalent
and
third
deadliest
in
Europe
among
men.
PCa
has
several
well-established
risk
factors;
however,
influence
lifestyle
factors
remains
under
investigation,
which
may
hinder
efforts
to
encourage
healthier
behavior
adoption.
Thus,
this
systematic
review
explored
general
population’s
perceptions,
knowledge,
attitudes
regarding
PCa-related
factors.
Recent
Findings
Eighteen
qualitative
studies
were
included
after
searching
PubMed,
Scopus,
Web
Science,
EMBASE
scientific
databases
between
January
2013
February
2023.
Five
major
themes
emerged
from
18
studies:
factors,
pattern
changes,
motivation/barriers
changing
habits,
advice
support.
Participants
identified
age,
family
history,
genetics,
race/ethnicity
as
for
PCa,
but
no
consensus
been
reached
lifestyle.
However,
participants
willing
adopt
habits.
Support
healthcare
professionals
(HPs),
family,
friends,
desire
more
time
with
loved
ones,
fear
consequences
cited
motivators
habit
changes.
poor
economic
conditions,
work
schedules,
limitations
hamper
Summary
Effective
interventions
require
personalized
support
credible
information
providers.
Collaboration
HPs
crucial
promoting
behaviors
enhancing
management.
This
highlights
need
further
research
innovative
approaches
empower
individuals
towards
lifestyles,
could
help
prevent
or,
at
very
least,
promote
better
treatment
outcomes.
Graphical
Food Science & Nutrition,
Год журнала:
2025,
Номер
13(3)
Опубликована: Март 1, 2025
ABSTRACT
Phytochemicals
are
bioactive
compounds
found
in
plants
that
play
a
key
role
promoting
health
and
preventing
diseases.
Present
fruits,
vegetables,
grains,
seed
oils,
these
considered
safe
for
consumption
due
to
the
co‐evolution
adaptation
between
mammals
plants.
Due
their
wide‐ranging
biological
effects,
they
have
attracted
considerable
research
interest.
This
comprehensive
review
explores
mechanisms
of
action,
benefits,
applications
dietary
phytochemicals,
with
particular
focus
on
groups
such
as
polyphenols,
flavonoids,
carotenoids.
Research
shows
phytochemicals
interact
nuclear
membrane
receptors,
influence
metabolic
pathways,
affect
epigenetic
modifications.
Our
highlights
broad
range
activities
compounds,
including
antioxidant,
antibacterial,
anti‐inflammatory,
anti‐diabetic,
anticancer
all
which
contribute
health‐promoting
properties.
Clinical
evidence
supports
prevention
management
diseases
cardiovascular
disorders,
conditions,
cancer,
diets
rich
being
linked
lower
risk
disease.
also
at
cutting
edge
food
preservation,
supplements,
emerging
medical
treatments.
Additionally,
we
identified
advancements
extraction
identification
techniques,
particularly
metabolomics,
further
enhance
areas.
Despite
promising
challenges
bioavailability,
regulatory
barriers,
need
robust
clinical
trials
persist.
However,
innovative
delivery
systems
like
nanoparticles,
liposomes,
encapsulation
offer
potential
solutions
bioavailability
by
improving
absorption
stability.
The
concludes
emphasizing
personalized
nutrition
combination
therapies
benefits
while
stressing
methods,
trials,
bioavailability.
Antioxidants,
Год журнала:
2023,
Номер
12(2), С. 289 - 289
Опубликована: Янв. 27, 2023
To
date,
it
is
known
that
antioxidants
protect
cells
from
damage
caused
by
oxidative
stress
and
associated
with
pathological
conditions.
Several
studies
have
established
inflammation
a
state
anticipates
the
neoplastic
transformation
of
prostate.
Although
many
experimental
clinical
data
indicated
efficacy
in
preventing
this
form
cancer,
discrepant
results,
especially
recent
large-scale
randomized
trials,
make
difficult
to
establish
real
role
for
prostate
tumor.
Despite
these
concerns,
safety
show
some
still
hold
promise
cancer
chemoprevention.
more
are
needed,
review,
we
briefly
describe
most
common
shown
benefits
preclinical
settings,
focusing
our
attention
on
synthesizing
advances
made
so
far
chemoprevention
using
as
interesting
molecules
challenges
future
therapies.
