Nutrients,
Год журнала:
2024,
Номер
17(1), С. 104 - 104
Опубликована: Дек. 30, 2024
Background
and
objectives:
Depression
often
results
in
premature
aging,
which
increases
the
risk
of
other
chronic
diseases,
but
very
few
studies
have
analyzed
association
between
epigenetic
biomarkers
aging
depressive
symptoms.
Similarly,
limited
research
has
examined
joint
effects
adherence
to
Mediterranean
diet
(MedDiet)
chronotype
on
symptoms,
accounting
for
sex
differences.
Therefore,
these
are
objectives
our
investigation
a
population
at
high
cardiovascular
risk.
Methods:
We
465
older
subjects
(aged
55–75)
with
metabolic
syndrome
assessed
symptoms
by
Beck
Inventory
(BDI-II).
MedDiet
was
measured
17-item
score,
Morningness–Eveningness
Questionnaire
(MEQ).
Blood
DNA
methylation
analyzed,
epigenomic
age
acceleration
were
determined.
focused
Dunedin
Pace
Aging
Computed
from
Epigenome
(DunedinPACE).
fitted
multivariable
models
interaction
terms.
Results:
Prevalence
depression
statistically
higher
women
(p
<
0.001).
strongly
inversely
associated
whole
0.01),
while
MEQ
score
0.05).
In
analysis,
both
remained
BDI-II
0.05),
showing
additive
effects.
No
observed.
women,
significantly
faster
(measured
DunedinPACE
biomarker).
This
significant
even
after
adjustment
chronotype.
Conclusions:
syndrome,
eveningness
greater
could
potentially
counteract
Women
showed
stronger
associations,
importantly,
we
reported
first
time
this
that
accelerated
aging.
Alimentary Pharmacology & Therapeutics,
Год журнала:
2024,
Номер
60(9), С. 1215 - 1233
Опубликована: Авг. 20, 2024
Summary
Background
Dietary
management
of
patients
with
inflammatory
bowel
disease
(IBD)
involves
more
than
defining
a
therapeutic
diet.
The
profusion
‘expert
advice’
is
not
necessarily
built
on
evidence.
Aims
To
provide
evidence‐based
guidance
all
clinically
relevant
aspects
nutritional
and
dietary
IBD.
Methods
A
comprehensive
review
the
published
literature
was
made.
Results
Four
pillars
should
be
considered
in
patients.
First,
status
optimised,
since
myopenia
visceral
obesity
are
associated
poorer
outcomes,
which
can
improved
attention
to
their
correction.
Accurate
point‐of‐care
measurement
body
composition
advocated
identify
problems,
guide
interventions
monitor
outcomes.
Second,
exclusive
enteral
nutrition
Crohn's
Disease
Exclusion
Diet
partial
reducing
intestinal
inflammation
have
sufficient
evidence
advocated.
Multiple
other
approaches,
while
promising,
insufficient
recommended.
Third,
approaches
important
symptomatic
control
many
non‐inflammatory
scenarios.
Finally,
following
healthy
diet
fundamental
general
health
advocated,
but
optimal
strategy
unclear.
precarious
IBD
together
risks
inadequacy
maladaptive
eating
behaviours
restrictive
diets
dictate
involvement
expert
dietitians
assessment
personalised
delivery
interventions.
Conclusions
require
specific
interventional
strategies
that
chosen
by
Optimal
requires
skills
specialised
dietitian.
Nutrients,
Год журнала:
2025,
Номер
17(3), С. 563 - 563
Опубликована: Янв. 31, 2025
Objectives:
This
study
aimed
to
investigate
the
effects
of
different
dietary
patterns
on
depressive
disorders.
Methods:
PubMed/MEDLINE,
Cochrane
CENTRAL,
Embase,
PsycINFO,
Scopus,
and
ProQuest
databases
were
systematically
searched
until
30
April
2024
for
randomized
controlled
trials
(RCTs)
assessing
symptoms
in
adults
with
Secondary
outcomes
included
remission
rates,
quality
life,
safety.
Standardized
mean
difference
(SMD)
95%
confidence
intervals
(CIs)
aggregated
using
a
random-effects
model.
Study
was
assessed
Risk
Bias
(RoB)-2
tool,
certainty
evidence
determined
Grading
Recommendations,
Assessment,
Development,
Evaluation
(GRADE)
approach.
Results:
Five
RCTs
(n
=
952)
included,
all
investigating
Mediterranean
diet
(MD)
individuals
major
disorder
or
elevated
depression
levels.
The
analysis
found
no
significant
effect
short-term
MD
intervention
severity
compared
active
(SMD
−1.25
[95%
CI:
−5.11
2.61])
passive
−0.22
−0.74
0.29])
controls.
There
life
controls
0.71
CI
−3.38
4.79]).
Intermediate
long-term
results
similar.
overall
risk
bias
“some
concerns”,
“very
low”
most
results.
Conclusions:
appears
have
potential
influence
disorder.
However,
this
finding
should
be
interpreted
cautiously
due
limited
number
RCTs.
Further
studies
disorders
are
needed
more
robust
conclusions.
Systematic
Review
Registration:
PROSPERO
registration
no.
CRD42024541885.
Canadian Medical Association Journal,
Год журнала:
2025,
Номер
197(2), С. E54 - E55
Опубликована: Янв. 19, 2025
[Voir
la
version
anglaise
de
l'article
ici
:
www.cmaj.ca/lookup/doi/10.1503/cmaj.240440][1]
Selon
une
métarevue
2024
—
regroupant
près
10
millions
personnes
participantes
à
des
études
observationnelles
les
qui
consomment
davantage
d'aliments
ultratransformés
pré
Journal of Basic and Clinical Health Sciences,
Год журнала:
2025,
Номер
9(1), С. 131 - 140
Опубликована: Янв. 31, 2025
Purpose:
This
research
aimed
to
investigate
the
effects
of
adherence
Mediterranean
diet
(MD)
on
depression
risk
in
young
adults
and
understand
potential
associations.
Material
Methods:
An
online
survey
form
was
sent
university
students
Türkiye,
479
participated
this
cross-sectional
study.
Adherence
MD
decided
using
Diet
Screener
(MEDAS).
Beck
Depression
Inventory
(BDI)
applied
measure
presence
manifestations
depression.
Multivariate
linear
regression
models
were
used
for
determinants
MEDAS
BDI
scores.
Results:
73
males
406
females
with
a
mean
age
21.6±2.3
years
body
mass
index
22.0±3.5
kg/m2
While
61.8%
had
moderate
MD,
54.9%
mild
or
level.
According
models,
regular
exercise,
NCD(s),
an
adequate/balanced
score's
determinants,
BMI
score
(p
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(6), С. 2759 - 2759
Опубликована: Март 19, 2025
It
is
known
that
the
effectiveness
of
drug
treatment
for
depression,
ammine
deficit
based,
largely
unsatisfactory.
In
this
review,
we
examine
proposal
a
precision
therapy
has
emerged
and
received
strong
push
by
identification
role
inflammation
in
depression.
However,
psychiatry
risks
being
caught
reductionist
trap
searching
molecular
switch
resets
whole
system
switches
off
disease.
This
an
illusion
since
human
complex
depression
systemic
variable
disorder.
study,
show
inadequacy
paradigm,
and,
at
same
time,
illustrate
superiority
paradigm
centered
on
psychoneuroendocrineimmunology
(PNEI).
According
to
PNEI
disease
being,
caused
different
sources
working
together:
psychological,
biological,
behavioral.
means
knowing
biological
psychological
history
subject,
identifying
relational
crisis
factors,
building
personalized
treatments
targeting
those
factors
with
tools
medicine
psychology,
which
are
not
reducible
combination
drugs
psychotherapy.
Our
presents
shift
both
theoretical
practical,
enables
clinicians
assess
patients
experiencing
unified
way
treat
them
integrated
manner.