Electrospun chitosan//ethylcellulose-vitamin E//ethylcellulose-curcumin tri-chamber eccentric Janus nanofibers for a joint antibacterial and antioxidant performance

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 135753 - 135753

Опубликована: Окт. 17, 2024

Язык: Английский

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Antibacterial and wound healing stimulant nanofibrous dressing consisting of soluplus and soy protein isolate loaded with mupirocin

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Ноя. 2, 2024

Abstract Severe cutaneous injuries may not heal spontaneously and necessitate the use of supplementary therapeutic methods. Electrospun nanofibers possess high porosity specific surface area, which provide necessary microenvironment for wound healing. Here in, Soluplus-soy protein isolate (Sol-SPI) containing mupirocin (Mp) were fabricated via electrospinning treatment. The exhibited water absorption capacities about 300.83 ± 29.72% vapor permeability values 821.8 49.12 g/m 2 day. Sol/SPI/Mp showed an in vitro degradability 33.73 3.55% after 5 days. ultimate tensile strength, elastic modulus, elongation measured as 3.61 0.29 MPa, 39.15 5.08 59.11 1.94%, respectively. Additionally, 85.90 6.02% Mp loaded was released days vitro, by applying Mp-loaded nanofibers, 93.06 5.40% 90.40 5.66% S. aureus E. coli bacteria killed, Human keratinocyte cells (HaCat) demonstrated notable biocompatibility with prepared nanofibers. Furthermore, compare to other groups, Sol-SPI-Mp caused fastest re-epithelialization healing a rat model. findings this study present novel nanofiber-based dressing that accelerates severe skin wounds risk infection.

Язык: Английский

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Fabrication and in Vivo Evaluation of Hybrid Squalene-Loaded Nanofiber Scaffolds Based on Poly(ε-Caprolactone)/Polyvinyl Alcohol/Chitosan for Wound Healing Applications

Journal of Polymers and the Environment, Год журнала: 2025, Номер unknown

Опубликована: Март 6, 2025

Язык: Английский

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Advances in the development of medical dressings for the treatment of diabetic foot wounds

Chemical Engineering Journal, Год журнала: 2024, Номер 498, С. 155575 - 155575

Опубликована: Сен. 7, 2024

Язык: Английский

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Conjugated electrospinning toward a polycaprolactone scaffold simultaneously containing micro-/nano- fibers for potential biomedical application

Journal of Polymer Research, Год журнала: 2024, Номер 31(10)

Опубликована: Сен. 29, 2024

Язык: Английский

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Smart macrophage-targeting wound dressings accelerate diabetic wound healing

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 156860 - 156860

Опубликована: Окт. 1, 2024

Язык: Английский

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Epigallocatechin gallate and vancomycin loaded poly(vinyl)-pyrrolidone-gelatine nanofibers, Conceivable curative approach for wound healing

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер 249, С. 114506 - 114506

Опубликована: Янв. 15, 2025

Язык: Английский

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Advancements in Wound Management: Microenvironment-Sensitive Bioactive Dressings with On-Demand Regulations for Diabetic Wounds

Engineering, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

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An Investigation on the Effect of Urea on the Electrospinnability of Polyvinyl Alcohol Solutions

Journal of Applied Polymer Science, Год журнала: 2025, Номер unknown

Опубликована: Апрель 6, 2025

ABSTRACT Polyvinyl alcohol (PVA) has been widely used in electrospinning due to its ease of processing and ability aid the challenging polymers. However, it is expensive. This study explores use urea, a highly water‐soluble, nitrogen‐rich (46%) compound, as cost‐effective alternative PVA aqueous solutions. Electrospinning PVA‐urea nanofibers containing up 75% urea was successfully achieved, with electrical conductivity identified key factor controlling fiber diameter. The diameter electrospun fibers ranged from 298 ± 42 nm 345 55 nm. FTIR analysis confirmed interactions between indicating cross‐linking macromolecules. X‐ray diffraction (XRD) patterns revealed crystallization within predominantly amorphous matrix at low concentrations. Cross‐linking glutaraldehyde reduced water solubility. results also showed that solubility decreased by about 90% after under acidic conditions. release followed Fickian Higuchi models, demonstrating controlled properties. Given cost availability, presents viable substitute for PVA, particularly applications where facilitate otherwise difficult‐to‐process

Язык: Английский

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A separable double-layer self-pumping dressing containing astragaloside for promoting wound healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136342 - 136342

Опубликована: Окт. 5, 2024

Язык: Английский

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