Enhancement Effect of Static Magnetic Field on Bactericidal Activity DOI Open Access
Min Zhang, Yongshun Song, Jun Wang

и другие.

Small, Год журнала: 2025, Номер unknown

Опубликована: Март 22, 2025

Abstract The biological effects of magnetic fields are pervasive in microorganisms, with significant attention given to alternating (AMFs). However, AMFs induce electrical and magnetothermal effects, which complicate the interpretation field‐induced introduce uncertainties regarding cytotoxicity practical applications. static field (SMF) few variables high biocompatibility presents a promising alternative for both understanding mechanisms ensuring safe applications, but has remaining problem on weak interactions microorganisms. Here we show that combination SMF paramagnetic calcium‐polypyrrole nanoparticles (Ca‐PPy) remarkably enhances bactericidal activity. Our experiments indicate synergistic action Ca‐PPy significantly promotes generation reactive oxygen species (ROS), i.e., singlet superoxide anion radicals, Escherichia coli ( E. ) Staphylococcus aureus S. ), coupled physical disruption bacterial membrane, exhibiting extraordinary performance (the rate is over 94%). mechanism disclosed by computations singlet‐to‐triplet transition radical pairs can be increased introduction fields. These findings offer new insights into pave way their safe, highly effective use

Язык: Английский

An amplification mechanism for weak ELF magnetic fields quantum-bio effects in cancer cells DOI Creative Commons

Amirali Zandieh,

Seyed Peyman Shariatpanahi,

Amir Abas Ravassipour

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 23, 2025

Язык: Английский

Процитировано

2
Revolutionizing Food Sustainability: Leveraging Magnetic Fields for Food Processing and Preservation DOI
Bai Qu, Guoqiang Shao, Na Yang

и другие.

Trends in Food Science & Technology, Год журнала: 2024, Номер 150, С. 104593 - 104593

Опубликована: Июнь 12, 2024

Язык: Английский

Процитировано

9
The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk DOI Creative Commons
Kenneth Maiese

Frontiers in Immunology, Год журнала: 2023, Номер 14

Опубликована: Ноя. 8, 2023

Life expectancy is increasing throughout the world and coincides with a rise in non-communicable diseases (NCDs), especially for metabolic disease that includes diabetes mellitus (DM) neurodegenerative disorders. The debilitating effects of disorders influence entire body significantly affect nervous system impacting greater than one billion people disability peripheral as well cognitive loss, now seventh leading cause death worldwide. Metabolic disorders, such DM, neurologic remain significant challenge treatment care individuals since present therapies may limit symptoms but do not halt overall progression. These clinical challenges to address interplay between warrant innovative strategies can focus upon underlying mechanisms aging-related oxidative stress, cell senescence, death. Programmed pathways involve autophagy, apoptosis, ferroptosis, pyroptosis play critical role oversee processes include insulin resistance, β-cell function, mitochondrial integrity, reactive oxygen species release, inflammatory activation. silent mating type information regulation 2 homolog 1

Язык: Английский

Процитировано

20
Biological Effects of Magnetic Storms and ELF Magnetic Fields DOI Creative Commons

Ruslan M. Sarimov,

Dmitriy A. Serov, Sergey V. Gudkov

и другие.

Biology, Год журнала: 2023, Номер 12(12), С. 1506 - 1506

Опубликована: Дек. 8, 2023

Magnetic fields are a constant and essential part of our environment. The main components ambient magnetic the geomagnetic field, its fluctuations caused by storms, man-made fields. These refer to extremely-low-frequency (<1 kHz) (ELF-MFs). Since 1980s, huge amount data has been accumulated on biological effects fields, in particular ELF-MFs. However, unified picture patterns action not formed. Even though mechanism yet generally accepted, several theories have proposed. In this review, we attempted take new approach analyzing quantitative ELF-MFs identify potential areas for research. This review provides general descriptions storms anthropogenic living organisms (molecular-cellular level whole organism) brief description mechanisms field organisms. may be interest specialists biology, physics, medicine, other interdisciplinary areas.

Язык: Английский

Процитировано

19
Molecular Biological Effects of Weak Low-Frequency Magnetic Fields: Frequency–Amplitude Efficiency Windows and Possible Mechanisms DOI Open Access
В. В. Крылов, Elena A. Osipova

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(13), С. 10989 - 10989

Опубликована: Июль 1, 2023

This review covers the phenomenon of resonance-like responses biological systems to low-frequency magnetic fields (LFMF). The historical development this branch magnetobiology, including most notable biophysical models that explain LFMF with a specific frequency and amplitude, is given. Two groups can be distinguished among these models: one considers ion-cofactors proteins as primary targets for influence, other regards moments particles in biomolecules. Attention paid dependence effects on cell type. A radical-pair mechanism field’s influence biochemical processes described example cryptochrome. Conditions mechanism’s applicability are model radical pairs oscillators, which frequency–amplitude efficiency windows LFMF, proposed.

Язык: Английский

Процитировано

17
Spin chemistry in living systems DOI Creative Commons
P. J. Hore

National Science Review, Год журнала: 2024, Номер 11(9)

Опубликована: Март 28, 2024

Magnetobiology-the study of non-thermal effects magnetic fields on biological systems-has a vast, wide-ranging, and ever-expanding literature.Sadly, much it is beset by conflicting, implausible or extravagant claims.The credibility many reports marred shortcomings in experimental design description, inadequate controls, unblinded protocols, inappropriate statistical analysis, lack comparability with other studies, poor reproducibility.Careful attempts at direct independent replication are scarce frequently unsuccessful [1,2].Authors can be reluctant to write up, journal editors publish, others cite negative resulting an unbalanced literature.False positives no doubt abound.Raw data often not made publicly available.The magnetobiology literature must therefore viewed critical eye: everything should accepted face value.This shame.Magnetic field chemical systems have provided powerful insights into the structures dynamics molecules kinetics mechanisms their reactions [3,4].Related achievements possible biology, areas such as physiological anthropogenic fields, effectiveness therapies medical diagnostics, improvement crop yields, name but few.

Язык: Английский

Процитировано

8
Static magnetic fields as a factor in modification of tissue and cell structure: a review DOI Creative Commons
Bogdan Saletnik, Anna Puchalska-Sarna, Aneta Saletnik

и другие.

International Agrophysics, Год журнала: 2024, Номер 38(1), С. 43 - 75

Опубликована: Янв. 11, 2024

1. Abdolmaleki P., Ghanati F., Sahebjamei H., and Sarvestani A.S., 2007. Peroxidase activity, lignification promotion of cell death in tobacco cells exposed to static magnetic field. Environmentalist, 27, 435-440. https://doi.org/10.1007/s10669.... CrossRef Google Scholar

Язык: Английский

Процитировано

6
Quantum Control of Radical-Pair Dynamics beyond Time-Local Optimization DOI Creative Commons
Farhan T. Chowdhury, Matt C. J. Denton, Daniel C. Bonser

и другие.

PRX Quantum, Год журнала: 2024, Номер 5(2)

Опубликована: Апрель 4, 2024

We realize arbitrary-wave-form-based control of spin-selective recombination reactions radical pairs in the low-magnetic-field regime. To this end, we extend gradient-ascent pulse engineering (GRAPE) paradigm to allow for optimizing reaction yields. This overcomes drawbacks previously suggested time-local optimization approaches pairs, which were limited high biasing fields. demonstrate how efficient time-global yields can be realized by gradient-based methods augmented time blocking, sparse sampling yield, and evaluation central single time-step propagators their Fréchet derivatives using iterated Trotter-Suzuki splittings. Results are shown both a toy model, used coherent radical-pair simpler high-field scenario and, furthermore, realistic exciplex-forming donor-acceptor system comprising 16 nuclear spins. raises prospects spin actual systems ambient magnetic fields, suppressing or boosting purpose-specific radio-frequency wave forms, paving way reaction-yield-dependent quantum magnetometry potentially applications biochemical reactions. latter aspect two implicated biology.2 MoreReceived 26 June 2023Revised 15 January 2024Accepted 7 March 2024DOI:https://doi.org/10.1103/PRXQuantum.5.020303Published American Physical Society under terms Creative Commons Attribution 4.0 International license. Further distribution work must maintain attribution author(s) published article's title, journal citation, DOI.Published SocietyPhysics Subject Headings (PhySH)Research AreasChemical reactionsCoherent controlQuantum controlSpin coherenceSpin dynamicsPhysical SystemsQuantum modelsQuantum Information, Science & TechnologyAtomic, Molecular OpticalPhysics Living SystemsCondensed Matter, Materials Applied PhysicsInterdisciplinary Physics

Язык: Английский

Процитировано

6
On the optimality of the radical-pair quantum compass DOI Creative Commons
Luke D. Smith, Jonas Glatthard, Farhan T. Chowdhury

и другие.

Quantum Science and Technology, Год журнала: 2024, Номер 9(3), С. 035041 - 035041

Опубликована: Май 8, 2024

Abstract Quantum sensing enables the ultimate precision attainable in parameter estimation. Circumstantial evidence suggests that certain organisms, most notably migratory songbirds, also harness quantum-enhanced magnetic field via a radical-pair-based chemical compass for precise detection of weak geomagnetic field. However, what underpins acuity such operating noisy biological setting, at physiological temperatures, remains an open question. Here, we address fundamental limits inferring directions from radical-pair spin dynamics. Specifically, compare precision, as derived directional dependence recombination yield, to potentially realisable by quantum measurement on system under steady-state conditions. To this end, probe Fisher information and associated Cramér–Rao bound models realistic complexity, accounting complex inter-radical interactions, multitude hyperfine couplings, asymmetric kinetics, characteristic magnetosensory protein cryptochrome. We several implicated cryptochrome magnetoreception unveil their optimality through measurements ostensibly accessible nature. Overall, comparison provides insight into processes honed nature realise whilst constrained with mere reaction yields. Generally, inference orientation yields approaches yet levels off short theoretical optimal bounds up one or two orders magnitude, thus underscoring potential improving design principles inherent natural systems.

Язык: Английский

Процитировано

6
Weak magnetic fields modulate superoxide to control planarian regeneration DOI Creative Commons

Luke J. Kinsey,

Alanna V. Van Huizen, Wendy S. Beane

и другие.

Frontiers in Physics, Год журнала: 2023, Номер 10

Опубликована: Янв. 4, 2023

Reactive oxygen species (ROS) signaling regulates cell behaviors and tissue growth in development, regeneration, cancer. Commonly, ROS are modulated pharmacologically, which while effective comes with potential complications such as off-target effects lack of drug tolerance. Thus, additional non-invasive therapeutic methods necessary. Recent advances have highlighted the use weak magnetic fields (WMFs, &lt;1 mT) one promising approach. We previously showed that 200 μT WMFs inhibit formation block planarian regeneration. However, WMF research different model systems at various field strengths produced a range results do not fit common dose response curves, making it unclear if predictable. Here, we test hypotheses based on spin state theory radical pair mechanism, outlines how can alter pairs by changing electron states. This mechanism suggests across broad (0–900 μT) some exposures should be able to others promote binary fashion. Our data reveal used for directed manipulation stem proliferation, differentiation, predictable ways both loss gain function during regenerative growth. Furthermore, examine two most effectors, hydrogen peroxide superoxide, begin identification elucidation specific molecular targets affect Together, our cellular exposure highly dependent ROS, identify superoxide being modulated. Altogether, these highlight possibilities using control vivo represent an exciting new area research.

Язык: Английский

Процитировано

15