Marijuana Liberalization Policies and Perinatal Health DOI Open Access
Angélica Meinhofer, Allison Witman, Jesse M. Hinde

и другие.

Опубликована: Сен. 1, 2021

We studied the effect of marijuana liberalization policies on perinatal health with a multiperiod difference-in-differences estimator that exploited variation in effective dates medical laws (MML) and recreational (RML).We found proportion maternal hospitalizations use disorder increased by 23% (0.3 percentage points) first three years after RML implementation, larger effects states authorizing commercial sales marijuana.This growth was accompanied 7% (0.4 decline tobacco hospitalizations, yielding net zero over all substance hospitalizations.RMLs were not associated changes newborn health.MMLs had no significant nor fairly small could be ruled out.In absolute numbers, our findings implied modest or adverse array outcomes considered.

Язык: Английский

Health, safety, and socioeconomic impacts of cannabis liberalization laws: An evidence and gap map DOI Creative Commons
Eric L. Sevigny,

Jared Greathouse,

Danye N. Medhin

и другие.

Campbell Systematic Reviews, Год журнала: 2023, Номер 19(4)

Опубликована: Окт. 30, 2023

Abstract Background Globally, cannabis laws and regulations are rapidly changing. Countries increasingly permitting access to under various decriminalization, medicalization, legalization laws. With strong economic, public health, social justice incentives driving these domestic policy reforms, liberalization trends bound continue. However, despite a large growing body of interdisciplinary research addressing the policy‐relevant safety, socioeconomic consequences liberalization, there is lack robust primary systematic that comprehensively investigates reforms. Objectives This evidence gap map (EGM) summarizes empirical on policies. Primary objectives were develop conceptual framework linking policies relevant outcomes, descriptively summarize evidence, identify areas concentration gaps. Search Methods We searched for eligible English‐language studies published across 23 academic databases 11 gray literature sources through August 2020. Additions pool potentially from supplemental made November Selection Criteria The this EGM draws upon legal epidemiological perspective highlighting causal effects law population‐level outcomes. Eligible interventions include create or expand decriminalized supply cannabis: comprehensive medical (MCLs), limited cannabidiol (CBDLs), recreational (RCLs), industrial hemp (IHLs), decriminalization cultivations (DCLs). outcomes intermediate responses (i.e., attitudes/behaviors markets/environments) longer‐term (health, outcomes) Data Collection Analysis Both dual screening data extraction performed with third person deconfliction. appraised using Maryland Scientific Scale reviews assessed AMSTAR 2. Main Results includes 447 studies, comprising 438 nine reviews. Most derives United States, little other countries. By far, most focuses MCLs RCLs. Studies targeting laws—including CBDLs, IHLs, DCLs—are relatively rare. Of 113 distinct we documented, use was single frequently investigated. More than half addressed by three fewer substantial gaps in literature. base small, just seven completed (3), opioid‐related harms alcohol‐related (1). Moreover, have confidence reviews, as five minimal quality two low quality. Authors’ Conclusions needed better understand longer‐term—and arguably more salient—health, Since concerns RCLs, critical need societal impacts production, CBD products, cultivation. Future should also prioritize understanding heterogeneous given differences specific provisions implementation jurisdictions.

Язык: Английский

Процитировано

6
Associations between cannabis policies and state-level specialty cannabis use disorder treatment in the United States, 2004–2019 DOI Creative Commons
Pia M. Mauro, Sarah Gutkind, Melanie S. Askari

и другие.

Drug and Alcohol Dependence, Год журнала: 2024, Номер 257, С. 111113 - 111113

Опубликована: Фев. 2, 2024

Язык: Английский

Процитировано

2
Marijuana liberalization policies and perinatal health DOI Creative Commons
Angélica Meinhofer, Allison Witman, Jesse M. Hinde

и другие.

Journal of Health Economics, Год журнала: 2021, Номер 80, С. 102537 - 102537

Опубликована: Сен. 27, 2021

Язык: Английский

Процитировано

12
United States marijuana legalization and opioid mortality epidemic during 2010–2020 and pandemic implications DOI
Archie Bleyer, Brian J. Barnes, Kenneth Finn

и другие.

Journal of the National Medical Association, Год журнала: 2022, Номер 114(4), С. 412 - 425

Опубликована: Апрель 22, 2022

Язык: Английский

Процитировано

9
Marijuana, Opioid, and Alcohol Use Among Pregnant and Postpartum Individuals Living With HIV in the US DOI Creative Commons
Lynn M. Yee, Deborah Kacanek,

Chase Brightwell

и другие.

JAMA Network Open, Год журнала: 2021, Номер 4(12), С. e2137162 - e2137162

Опубликована: Дек. 3, 2021

Importance

Amid the opioid epidemic and evolving legal social changes with marijuana, little is known about substance use among pregnant postpartum people living HIV.

Objectives

To evaluate trends in alcohol, during pregnancy first year US HIV differences based on marijuana legalization status.

Design, Setting, Participants

Data from Surveillance Monitoring for Antiretroviral Toxicities (SMARTT) study of Pediatric HIV/AIDS Cohort Study were analyzed. SMARTT-enrolled, at 22 sites January 1, 2007, to July 2019, self-reported data available pregnancy, 1 postpartum, or both assessed.

Exposures

Calendar state

Main Outcomes Measures

The prevalence any each following substances was calculated by calendar year, separately postpartum: opioid, concomitant alcohol marijuana. Log binomial models fit using general estimating equations mean annual change, accounting repeat pregnancies. also evaluated recreational medical

Results

Substance 2926 pregnancies 2310 (mean [SD] age, 28.8 [6.1] years; 822 [28.1%] Hispanic, 1859 [63.5%] non-Hispanic Black, 185 [6.3%] White, 24 [0.8%] more than race, other race ethnicity [individuals who identified as American Indian, Asian, Native Hawaiian Pacific Islander], 12 [0.4%] unknown unreported ethnicity). Between 2007 increased 7.1% 11.7%, whereas unchanged. Postpartum (44.4%), (13.6%), (10.0%) common; 10.2% 23.7% adjusted risk 7% (95% CI, 3%-10%) per 11% 7%-16%) postpartum. 10% 5%-15%) year. Differences not associated legalization, but legalization.

Conclusions Relevance

In this cohort study, remained stable, over time states legalized These patterns increasing suggest that enhanced clinical attention warranted, given potential maternal child health implications use.

Язык: Английский

Процитировано

11
CUL4A‐mediated ZEB1/microRNA‐340‐5p/HMGB1 axis promotes the development of osteoporosis DOI
Hongliang Chen, Qiang Zheng,

You Lv

и другие.

Journal of Biochemical and Molecular Toxicology, Год журнала: 2023, Номер 37(8)

Опубликована: Май 30, 2023

Understanding the molecular mechanisms underlying osteoclast differentiation provides insights into bone loss and even osteoporosis. The specific mechanistic actions of cullin 4A (CUL4A) in resultant osteoporosis is poorly explored. We developed a mouse model using bilateral ovariectomy (OVX) examined CUL4A expression. It was noted that expression increased marrow OVX mice. Overexpression promoted differentiation, knockdown alleviated symptoms Bioinformatic analyses were applied to identify downstream target genes microRNA-340-5p (miR-340-5p), followed by interaction analysis. macrophages (BMMs) isolated from femur mice, which transfected with different plasmids alter CUL4A, Zinc finer E-box binding homeobox 1 (ZEB1), miR-340-5p, Toll-like receptor 4 (TLR4). ChIP assay performed detect enrichment ZEB1 promoter H3K4me3 antibody BMMs. overexpressed mediated methylation increase expression, thus promoting differentiation. Meanwhile, could inhibit miR-340-5p upregulate HMGB1 induce Overexpressed activated TLR4 pathway regulating miR-340-5p/HMGB1 axis development Overall, E3 ubiquitin ligase can repress leading upregulation activation, promotes

Язык: Английский

Процитировано

4
The effect of cannabis policies on treatment outcomes for cannabis use among U.S. adults DOI
Jessica L. Bourdon, Meredith W. Francis, Lena Jia

и другие.

Journal of Substance Abuse Treatment, Год журнала: 2021, Номер 131, С. 108535 - 108535

Опубликована: Июнь 11, 2021

Язык: Английский

Процитировано

9
United States marijuana legalization and opioid mortality trends before and during the first year of the COVID-19 pandemic DOI
Archie Bleyer, Brian J. Barnes, Kenneth Finn

и другие.

Journal of Opioid Management, Год журнала: 2024, Номер 20(2), С. 119 - 132

Опубликована: Апрель 1, 2024

To determine if marijuana legalization was associated with reduced opioid mortality.

Язык: Английский

Процитировано

1
Changes in prenatal cannabis‐related diagnosed disorders after the Cannabis Act and the COVID‐19 pandemic in Quebec, Canada DOI Creative Commons
José Ignacio Nazif‐Muñoz, Pablo Martínez, Christophe Huỳnh

и другие.

Addiction, Год журнала: 2024, Номер 119(10), С. 1784 - 1791

Опубликована: Июнь 19, 2024

Public health concerns regarding pregnant women's after the enactment of Cannabis Act in Canada (CAC) (a law that allowed non-medical cannabis use), and potential impact COVID-19 pandemic, call for a contemporary assessment these two events. Our study measured associations between CAC, pandemic monthly prevalence rates cannabis-, all drug- alcohol-related diagnosed disorders among women province Quebec.

Язык: Английский

Процитировано

1
Association between state‐level medical marijuana legalization and marijuana use during pregnancy: A population‐based study DOI Creative Commons
Mohammad Rifat Haider, Sabrina A. Karim, Jayani Jayawardhana

и другие.

American Journal on Addictions, Год журнала: 2024, Номер unknown

Опубликована: Сен. 29, 2024

Abstract Background and Objectives Despite marijuana's association with adverse pregnancy birth outcomes, its use during increased over the last two decades. During this period, medical marijuana has been legalized in 38 states District of Columbia. States have observed marketing related products. This study aims to examine between state‐level legalization United States. Methods Using 2015–2021 National Survey on Drug Use Health, we evaluated past month among currently pregnant mothers ( N = 4338) their state residence. Survey‐weighted descriptive, bivariate, multivariable logistic regression analyzes were performed. Results About 5.7% women reported using month, 59.0% lived a where was across 2015–2021. Compared those living without legalization, more (4.6% vs. 6.5%). In model, residing likely than residents (adjusted Odds Ratio: 1.56; 95% Confidence Interval: 1.11–2.18). Conclusion Scientific Significance is first known find that are pregnancy. Pregnant should be informed outcomes linked

Язык: Английский

Процитировано

1