Advances in immunology of male reproductive toxicity induced by common environmental pollutants

Environment International, Год журнала: 2024, Номер 190, С. 108898 - 108898

Опубликована: Июль 20, 2024

Humans are exposed to an ever-increasing number of environmental toxicants, some which have gradually been identified as major risk factors for male reproductive health, even associated with infertility. Male infertility is usually due the system damage, may be influenced by exposure contaminants such heavy metals, plasticizers, along genetics and lifestyle. Testicular immune microenvironment (TIM) important in maintaining normal physiological functions testis, whether disturbed TIM after toxicants could induce toxicity remains explored. Therefore, current review aims contribute further understanding characterizing exposures effect on TIM. We first summarized phenotypes induced common pollutants. Contaminants including metals plastic additives fine particulate matter (PM

Язык: Английский

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Ashwagandha Diminishes Hippocampal Apoptosis Induced by Microwave Radiation by Acetylcholinesterase Dependent Neuro-Inflammatory Pathway in Male Coturnix coturnix Japonica

Neurochemical Research, Год журнала: 2024, Номер 49(7), С. 1687 - 1702

Опубликована: Март 20, 2024

Язык: Английский

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Role of Synbiotics (Prebiotics and Probiotics) as Dietary Supplements in Type 2 Diabetes Mellitus Induced Health Complications

Journal of Dietary Supplements, Год журнала: 2024, Номер 21(5), С. 677 - 708

Опубликована: Апрель 15, 2024

Diabetes is a metabolic disorder whose prevalence has become worrying condition in recent decades. Chronic diabetes can result serious health conditions such as impaired kidney function, stroke, blindness, and myocardial infarction. Despite variety of currently available treatments, cases its complications are on the rise. This review article provides comprehensive account ameliorative effect prebiotics probiotics individually or combination i.e. synbiotics induced by Type 2 Mellitus (T2DM). Recent advances field underscore encouraging outcomes suggesting consumption leads to favorable changes gut microbiota. These production bioactive metabolites short-chain fatty acids (crucial for lowering blood sugar levels), reducing inflammation, preventing insulin resistance, release glucagon-like peptide-1 host. Notably, novel strategies supplementing support microbiota gaining attraction pivotal interventions mitigating T2DM-induced complications. Thus, nurturing symbiotic relationship between synbiotics, these hold promise reshaping microbial landscape thereby offering multifaceted approach managing T2DM associated morbidities. Supporting potential underscores paradigm shift toward holistic targeted management, prospects improved enhanced quality life affected individuals. Nevertheless, more research needs be done better understand single multispecies pre/pro prevention management

Язык: Английский

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From Hypoxia to Oxidative Stress: Antioxidants’ Role to Reduce Male Reproductive Damage

Reproductive Sciences, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 18, 2024

Язык: Английский

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Histopathological alterations and oxidative stress markers in Clarias batrachus (Linnaeus, 1758) infested with nematode parasite

Journal of Parasitic Diseases, Год журнала: 2024, Номер unknown

Опубликована: Дек. 23, 2024

Язык: Английский

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