Journal of Neuroscience,
Год журнала:
2023,
Номер
44(5), С. e1024232023 - e1024232023
Опубликована: Дек. 11, 2023
White
matter
dysmaturation
is
commonly
seen
in
preterm
infants
admitted
to
the
neonatal
intensive
care
unit
(NICU).
Animal
research
has
shown
that
active
sleep
essential
for
early
brain
plasticity.
This
study
aimed
determine
potential
of
as
an
predictor
subsequent
white
development
infants.
Using
heart
and
respiratory
rates
routinely
monitored
NICU,
we
developed
a
machine
learning-based
automated
stage
classifier
cohort
25
(12
females).
The
was
subsequently
applied
58
(31
females)
extract
percentage
over
5–7
consecutive
days
during
29–32
weeks
postmenstrual
age.
Each
underwent
high-quality
T2-weighted
magnetic
resonance
imaging
at
term-equivalent
age,
which
used
measure
total
volume.
association
between
volume
examined
using
multiple
linear
regression
model
adjusted
confounders.
with
superior
classification
performance
[mean
area
under
receiver
operating
characteristic
curve
(AUROC)
=
0.87,
95%
CI
0.83–0.92],
found
higher
period
significantly
associated
increased
age
[
β
0.31,
0.09–0.53,
false
discovery
rate
(FDR)-adjusted
p
-value
0.021].
Our
results
extend
positive
animal
human
emphasize
benefit
preservation
NICU
setting.
Scientific Reports,
Год журнала:
2022,
Номер
12(1)
Опубликована: Май 5, 2022
Abstract
Healthy
sleep
supports
robust
development
of
the
brain
and
behavior.
Modern
society
presents
a
host
challenges
that
can
impair
disrupt
critical
circadian
rhythms
reinforce
optimal
physiological
functioning,
including
proper
timing
consolidation
sleep.
While
acute
effects
inadequate
disrupted
are
being
defined,
adverse
developmental
consequences
understudied.
Here,
we
exposed
mice
to
disrupting
light–dark
cycles
from
birth
until
weaning
demonstrate
such
exposure
has
impacts
on
behavior
as
adults.
Mice
experience
early-life
disruption
exhibit
more
anxiety-like
in
elevated
plus
maze,
poorer
spatial
memory
Morris
Water
Maze,
impaired
working
delayed
match-to-sample
task.
Additionally,
neuron
morphology
amygdala,
hippocampus
prefrontal
cortex
is
adversely
impacted.
Pyramidal
cells
these
areas
had
smaller
dendritic
fields,
pyramidal
also
exhibited
diminished
branching
orders.
Disrupted
were
hyperactive
adults,
but
otherwise
no
alteration
adult
locomotor
rhythms.
These
results
highlight
early
life
may
have
long
lasting
far-reaching
for
brain.
Journal of Personalized Medicine,
Год журнала:
2024,
Номер
14(1), С. 118 - 118
Опубликована: Янв. 20, 2024
The
relationship
between
sleep
and
epilepsy
is
bidirectional.
Certain
syndromes
predominantly
or
exclusively
manifest
during
sleep,
with
seizures
frequently
originating
from
non-rapid
eye
movement
(NREM)
sleep.
Interictal
epileptiform
discharges
observed
on
electroencephalograms
are
most
likely
to
be
activated
the
deep
NREM
stage
known
as
N3.
Conversely,
discharges,
anti-seizure
medications
(ASMs),
well
other
therapies
can
exert
detrimental
effects
architecture.
Moreover,
co-occurrence
of
disorders
has
potential
exacerbate
seizure
control.
Understating
crucial
for
healthcare
providers.
Addressing
managing
sleep-related
problems
in
individuals
potentially
contribute
improved
control
overall
well-being.
At
same
time,
improving
improve
quality
quantity,
thus
further
health
epilepsy.
Journal of Advanced Nursing,
Год журнала:
2024,
Номер
80(7), С. 2772 - 2784
Опубликована: Янв. 18, 2024
Abstract
Aims
The
objective
of
this
study
is
to
explore
the
various
latent
categories
within
sleep
quality
night
shift
nurses
and
investigate
whether
shift‐related
factors
predispose
higher
levels
occupational
stress
anxiety.
Design
This
a
cross‐sectional
study.
Methods
From
November
December
2020,
registered
from
18
tertiary
hospitals
16
secondary
in
Chongqing
were
selected
through
convenience
sampling
for
Latent
class
analysis
was
used
working
shifts.
Furthermore,
univariate
logistic
multivariate
utilized
identify
contributing
Results
four
Pittsburgh
Sleep
Quality
Index
identified
as
‘Low
Disorder
Group’
(56.34%),
‘Moderate
(37.27%),
‘High
Non‐Reliant
on
Sleeping
medication
(4.89%)
Reliant
(1.50%).
results
showed
that
having
night‐shift
frequency
3–4
times
per
month,
durations
9–12
h,
time
delay
after
(≥2
h),
total
less
than
4
h
increased
Conclusion
demonstrates
heterogeneity
can
be
classified
into
categories.
Higher
shifts,
extended
work
hours
insufficient
rest
are
all
associated
with
Impact
By
identifying
among
nurses,
sheds
light
relationship
between
patterns
These
findings
have
important
implications
healthcare
institutions
management
nurse
well‐being
schedules.
Patient
or
Public
Contribution
No
patient
public
contribution.
Sleep Medicine,
Год журнала:
2021,
Номер
82, С. 1 - 8
Опубликована: Март 30, 2021
Unobtrusive
monitoring
of
sleep
and
disorders
in
children
presents
challenges.
We
investigated
the
possibility
using
Ultra-Wide
band
(UWB)
radar
to
measure
children.Thirty-two
scheduled
undergo
a
clinical
polysomnography
participated;
their
ages
ranged
from
2
months
14
years.
During
polysomnography,
children's
body
movements
breathing
rate
were
measured
by
an
UWB-radar.
A
total
38
features
calculated
motion
signals
obtained
raw
signals.
Adaptive
boosting
was
used
as
machine
learning
classifier
estimate
stages,
with
gold
standard
method
for
comparison.Data
all
participants
combined,
this
study
achieved
Cohen's
Kappa
coefficient
0.67
overall
accuracy
89.8%
wake
classification,
0.47
72.9%
wake,
rapid-eye-movement
(REM)
sleep,
non-REM
0.43
58.0%
REM
light
deep
classification.Although
current
performance
is
not
sufficient
use
yet,
UWB
promising
non-contact
analysis
children.
Sleep Medicine Reviews,
Год журнала:
2021,
Номер
58, С. 101462 - 101462
Опубликована: Март 14, 2021
Cardiorespiratory
activity
is
highly
associated
with
infants'
sleep
duration
and
quality.
We
performed
a
systematic
literature
search
of
PubMed
EMBASE
databases
to
investigate
if
how
cardiorespiratory
parameters
can
be
used
for
state
classification
in
preterm
infants
what
way
maturation
influences
this
relation.
All
retrieved
citations
were
screened
against
predetermined
inclusion
exclusion
criteria.
Only
studies
(<37
wk
postmenstrual
age
during
classification)
admitted
neonatal
ward
whom
at
least
one
parameter
was
measured,
included.
Two
researchers
independently
reviewed
the
included
on
methodological
Of
1097
initially
studies,
23
analysis.
Heart
rate
respiration
frequency
are
strongly
correlated
active
quiet
sleep.
In
sleep,
as
compared
respiratory
more
stable,
heart
lower
less
variable.
This
association,
however,
differed
across
birth
subtypes
(i.e.,
extremely,
very
or
late
preterm),
indicating
that
–
form
both
gestational
postnatal
characteristics
states.
The
knowledge
gained
from
review
help
improve
behavioral
automated
algorithms
infants.
Science Translational Medicine,
Год журнала:
2022,
Номер
14(664)
Опубликована: Сен. 28, 2022
Exposure
to
environmental
adversities
during
early
brain
development,
such
as
preterm
birth,
can
affect
organization.
Here,
we
studied
whether
development
of
cortical
activity
networks
in
infants
may
be
improved
by
a
multimodal
enrichment
via
bedside
facilitation
mother-infant
emotional
connection.
We
examined
functional
cortico-cortical
connectivity
at
term
age
using
high-density
electroencephalography
recordings
participating
randomized
controlled
trial
Family
Nurture
Intervention
(FNI).
Our
results
identify
several
large-scale,
frequency-specific
network
effects
FNI,
most
extensively
the
alpha
frequency
fronto-central
regions.
The
strength
this
was
correlated
later
neurocognitive
performance,
and
it
comparable
healthy
term-born
rather
than
receiving
standard
care.
These
findings
suggest
that
neurodevelopmental
care
biologically
driven
enrichment,
direct
human
Cerebral Cortex,
Год журнала:
2023,
Номер
33(21), С. 10820 - 10835
Опубликована: Сен. 16, 2023
Functional
brain
networks
are
assessed
differently
earlier
versus
later
in
development:
infants
almost
universally
scanned
asleep,
whereas
adults
typically
awake.
Observed
differences
between
infant
and
adult
functional
may
thus
reflect
differing
states
of
consciousness
rather
than
or
addition
to
developmental
changes.
We
explore
this
question
by
comparing
magnetic
resonance
imaging
(fMRI)
scans
during
natural
sleep
awake
movie-watching.
As
a
reference,
we
also
rest
Whole-brain
connectivity
was
more
similar
within
the
same
state
(sleep
movie
infants;
adults)
compared
with
across
states.
Indeed,
classifier
trained
on
patterns
robustly
decoded
even
generalized
adults;
interestingly,
did
not
generalize
as
well
infants.
Moreover,
overall
similarity
modulated
(stronger
for
rest)
but
(same
movie).
Nevertheless,
connections
that
drove
similarity,
particularly
frontoparietal
control
network,
were
state.
In
sum,
differs
states,
highlighting
value
fMRI
studying
over
development.
