Separations,
Год журнала:
2021,
Номер
8(5), С. 65 - 65
Опубликована: Май 12, 2021
Phenolic
compounds
are
plants’
bioactive
metabolites
that
have
been
studied
for
their
ability
to
confer
extensive
benefits
human
health.
As
currently
there
is
an
increased
interest
in
natural
identification
and
characterization,
new
analytical
methods
based
on
advanced
technologies
developed.
This
paper
summarizes
current
advances
the
state
of
art
polyphenols
quantification.
Analytical
techniques
ranging
from
high-pressure
liquid
chromatography
hyphenated
spectrometric
discussed.
The
topic
high-resolution
mass
spectrometry,
targeted
quantification
untargeted
comprehensive
chemical
profiling,
particularly
addressed.
Structure
elucidation
one
important
steps
products
research.
Mass
spectral
data
handling
approaches,
including
acquisition
mode
selection,
accurate
measurements,
elemental
composition,
library
search
algorithms
structure
confirmation
through
fragmentation
pathways,
Nutrients,
Год журнала:
2018,
Номер
10(5), С. 604 - 604
Опубликована: Май 12, 2018
Since
the
Seven
Countries
Study,
dietary
cholesterol
and
levels
of
serum
in
relation
to
development
chronic
diseases
have
been
somewhat
demonised.
However,
principles
Mediterranean
diet
relevant
data
linked
examples
people
living
five
blue
zones
demonstrate
that
key
longevity
prevention
disease
is
not
reduction
or
but
control
systemic
inflammation.
In
this
review,
we
present
all
supports
view
it
inflammation
induced
by
several
factors,
such
as
platelet-activating
factor
(PAF),
leads
onset
cardiovascular
(CVD)
rather
than
cholesterol.
The
reducing
incidence
CVD
activities
PAF
other
inflammatory
mediators
via
diet,
exercise,
healthy
lifestyle
choices.
studies
supporting
these
views
are
discussed
review.
European Journal of Sport Science,
Год журнала:
2018,
Номер
19(1), С. 71 - 85
Опубликована: Авг. 15, 2018
Abstract
Exercise‐induced
muscle
damage
(EIMD)
is
characterized
by
symptoms
that
present
both
immediately
and
for
up
to
14
days
after
the
initial
exercise
bout.
The
main
consequence
of
EIMD
athlete
loss
skeletal
function
soreness.
As
such,
numerous
nutrients
functional
foods
have
been
examined
their
potential
ameliorate
effects
accelerate
recovery,
which
purpose
many
nutritional
strategies
athlete.
However,
trade‐off
between
recovery
adaptation
rarely
considered.
For
example,
interventions
described
in
this
review
target
oxidative
stress
inflammation,
thought
contribute
but
are
also
crucial
process.
This
calls
into
question
whether
long
term
administration
supplements
used
indeed
best
practice.
rapidly
growing
area
sports
nutrition
will
benefit
from
careful
consideration
hormetic
effect
use
aids
damage.
provides
a
concise
overview
what
is,
its
causes
consequences
critically
evaluates
EIMD.
We
pragmatic
practical
summary
can
be
adopted
practitioners
direct
future
research,
with
pushing
field
better
consider
fine
balance
modulating
balance.
Nutrients,
Год журнала:
2020,
Номер
12(10), С. 2929 - 2929
Опубликована: Сен. 24, 2020
Plant-based
diets
are
associated
with
reduced
risk
of
lifestyle-induced
chronic
diseases.
The
thousands
phytochemicals
they
contain
implicated
in
cellular-based
mechanisms
to
promote
antioxidant
defense
and
reduce
inflammation.
While
recommendations
encourage
the
intake
fruits
vegetables,
most
people
fall
short
their
target
daily
intake.
Despite
need
increase
plant-food
consumption,
there
have
been
some
concerns
raised
about
whether
beneficial
because
various
'anti-nutrient'
compounds
contain.
Some
these
anti-nutrients
that
called
into
question
included
lectins,
oxalates,
goitrogens,
phytoestrogens,
phytates,
tannins.
As
a
result,
may
be
select
individuals
specific
health
conditions
who
elect
decrease
plant
food
despite
potential
benefits.
purpose
this
narrative
review
is
examine
science
'anti-nutrients'
weigh
evidence
pose
an
actual
threat.
International Journal of Environmental Research and Public Health,
Год журнала:
2020,
Номер
17(7), С. 2326 - 2326
Опубликована: Март 30, 2020
Heart
and
blood
vessels
disorders
comprise
one
of
the
main
causes
death
worldwide.
Pharmacologically
active
natural
compounds
have
been
used
as
a
complementary
therapy
in
cardiovascular
disease
around
world
traditional
way.
Dietary,
bioactive
compounds,
well
healthy
lifestyles,
are
considered
to
prevent
coronary
artery
diseases.
Pre-clinical
clinical
studies
reported
that
consumption
plant-food
derivatives
including
polyphenolic
peptides,
oligosaccharides,
vitamins,
unsaturated
fatty
acids
possess
protective
effects
on
This
review
aims
summarize
risk
factors,
pre-clinical
trials
related
cardioprotective
properties
plant-food-derived
compounds.
Molecular
mechanisms
by
exert
their
also
highlighted.
International Journal of Molecular Sciences,
Год журнала:
2017,
Номер
18(11), С. 2230 - 2230
Опубликована: Окт. 25, 2017
Neurological
disorders
such
as
stroke,
Alzheimer’s
and
Parkinson’s
diseases
are
associated
with
high
morbidity
mortality,
few
or
no
effective
options
available
for
their
treatment.
These
share
common
pathological
characteristics
like
the
induction
of
oxidative
stress,
abnormal
protein
aggregation,
perturbed
Ca2+
homeostasis,
excitotoxicity,
inflammation
apoptosis.
A
large
body
evidence
supports
beneficial
effects
Mediterranean
diet
in
preventing
neurodegeneration.
As
is
characterized
by
a
consumption
extra-virgin
olive
oil
it
has
been
hypothesized
that
oil,
particular
its
phenols,
could
be
responsible
effect
diet.
This
review
provides
an
updated
vision
properties
phenols
preventing/counteracting
both
acute
chronic
neurodegenerative
diseases.
Molecules,
Год журнала:
2023,
Номер
28(17), С. 6403 - 6403
Опубликована: Сен. 1, 2023
Fruits,
vegetables,
and
other
food
items
contain
phytochemicals
or
secondary
metabolites
which
may
be
considered
non-essential
nutrients
but
have
medicinal
importance.
These
dietary
exhibit
chemopreventive
therapeutic
effects
against
numerous
diseases.
Polyphenols
are
found
in
fruits,
grains.
compounds
several
health
benefits
such
as
immune
modulators,
vasodilators,
antioxidants.
This
review
focuses
on
recent
studies
using
polyphenols
to
treat
cardiovascular
disorders,
atherosclerosis,
vascular
endothelium
deficits.
We
focus
exploring
the
safety
of
highly
effective
ensure
their
maximum
impact
cardiac
abnormalities
discuss
epidemiological
evidence
intervention
trials
related
these
properties.
Kaempferol,
quercetin,
resveratrol
prevent
oxidative
stress
by
regulating
proteins
that
induce
oxidation
heart
tissues.
In
addition,
modulate
tone
vessels
releasing
nitric
oxide
(NO)
reducing
low-density
lipoprotein
(LDL)
atherosclerosis.
cardiomyocytes,
suppress
expression
inflammatory
markers
inhibit
production
inflammation
exert
an
anti-inflammatory
response.
Consequently,
diseases
strokes,
hypertension,
failure,
ischemic
disease
could
prevented
polyphenols.
Antioxidants,
Год журнала:
2023,
Номер
12(2), С. 281 - 281
Опубликована: Янв. 27, 2023
As
a
major
cause
of
morbidity
and
mortality
globally,
hypertension
remains
serious
threat
to
global
public
health.
Despite
the
availability
many
antihypertensive
medications,
several
hypertensive
individuals
are
resistant
standard
treatments,
unable
control
their
blood
pressure.
Regulation
renin-angiotensin-aldosterone
system
(RAAS)
controlling
pressure,
activation
immune
triggering
inflammation
production
reactive
oxygen
species,
leading
oxidative
stress
redox-sensitive
signaling,
have
been
implicated
in
pathogenesis
hypertension.
Thus,
besides
which
lower
arterial
antioxidant
medications
were
tested
improve
treatment.
We
review
discuss
role
pathophysiology
potential
use
antioxidants
management
its
associated
organ
damage.
Nutrients,
Год журнала:
2023,
Номер
15(6), С. 1440 - 1440
Опубликована: Март 16, 2023
Arterial
stiffness
is
often
increased
in
overweight/obese
subjects
before
the
development
of
hypertension.
It
also
one
earliest
indicators
cardiovascular
disease
risk
and
can
be
considered
a
good
predictor
subclinical
dysfunction.
significant
prognostic
factor
influencing
risk,
which
dietary
habits
modify.
Obese
patients
should
use
caloric-restricted
diet
because
it
augments
aortic
distensibility,
diminishes
pulse
wave
velocity
(PWV),
increases
activity
endothelial
nitric
oxide
synthases.
High
intake
saturated
fatty
acids
(SFA),
trans
fats,
cholesterol,
typical
for
Western
diet,
impairs
function
raises
brachial-ankle
PWV.
The
replacement
SFA
with
monounsaturated
(MUFA)
or
polyunsaturated
(PUFA)
derived
from
seafood
plants
arterial
stiffness.
dairy
product
(excluding
butter)
decreases
PWV
general
population.
high-sucrose
causes
toxic
hyperglycemia
Complex
carbohydrates
low
glycemic
index
(including
isomaltose)
recommended
to
keep
vascular
health.
high
sodium
(>10
g/day),
particularly
associated
potassium
consumption,
has
deleterious
effect
on
(↑
baPWV).
Since
vegetables
fruits
are
sources
vitamins
phytochemicals,
they
Thus,
recommendation
prevent
similar
Mediterranean
rich
products,
plant
oils,
fish,
minimal
red
meat
five
servings
daily.
British Journal of Pharmacology,
Год журнала:
2017,
Номер
174(11), С. 1177 - 1194
Опубликована: Май 12, 2017
Linked
Articles
This
article
is
part
of
a
themed
section
on
Principles
Pharmacological
Research
Nutraceuticals.
To
view
the
other
articles
in
this
visit
http://onlinelibrary.wiley.com/doi/10.1111/bph.v174.11/issuetoc