Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi,
Год журнала:
2025,
Номер
8(2), С. 505 - 518
Опубликована: Март 12, 2025
Sun
drying
is
one
of
the
oldest
methods
preserving
food,
including
vegetables.
This
process
reduces
moisture
content
vegetables,
inhibiting
growth
microorganisms
that
cause
spoilage
and
rot.
study
investigates
total
antioxidant/oxidant
status,
phenolic
compound,
oxidative
stress
index
in
sun-dried
vegetables
(okra,
hot,
sweet
peppers,
zucchini,
eggplant).
The
used
were
chosen
randomly.
status
prepared
methanol
was
analyzed
using
a
spectrophotometer
commercially
available
kits.
Total
compounds
based
on
Folin-Ciocalteu
reagent
method.
calculated
by
dividing
amount
antioxidants
oxidants
multiplying
100.
antioxidant
highest
okra
(6.568±0.22,
79.51±0.21
respectively).
oxidant
eggplant
(14.645±0.24).
zucchini
(0.249±0.00).
Consequently,
this
highlights
high
phenols,
emphasizing
their
potential
health
benefits
reducing
stress.
It
reaffirms
value
traditional
sun-drying
nutritional
integrity
These
findings
support
inclusion
diet
for
benefits.
Acta Pharmaceutica Sinica B,
Год журнала:
2024,
Номер
15(1), С. 15 - 34
Опубликована: Окт. 16, 2024
Neuroprotection
is
a
proactive
approach
to
safeguarding
the
nervous
system,
including
brain,
spinal
cord,
and
peripheral
nerves,
by
preventing
or
limiting
damage
nerve
cells
other
components.
It
primarily
defends
central
system
against
injury
from
acute
progressive
neurodegenerative
disorders.
Oxidative
stress,
an
imbalance
between
body's
natural
defense
mechanisms
generation
of
reactive
oxygen
species,
crucial
in
developing
neurological
Due
its
high
metabolic
rate
consumption,
brain
particularly
vulnerable
oxidative
stress.
Excessive
ROS
damages
essential
biomolecules,
leading
cellular
malfunction
neurodegeneration.
Several
disorders,
Alzheimer's,
Parkinson's,
Amyotrophic
lateral
sclerosis,
multiple
ischemic
stroke,
are
associated
with
Understanding
impact
stress
these
conditions
for
new
treatment
methods.
Researchers
exploring
using
antioxidants
molecules
mitigate
aiming
prevent
slow
down
progression
diseases.
By
understanding
intricate
interplay
scientists
hope
pave
way
innovative
therapeutic
preventive
approaches,
ultimately
improving
individuals'
living
standards.
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(19), С. 14876 - 14876
Опубликована: Окт. 4, 2023
SARS-CoV-2
infection,
discovered
and
isolated
in
Wuhan
City,
Hubei
Province,
China,
causes
acute
atypical
respiratory
symptoms
has
led
to
profound
changes
our
lives.
COVID-19
is
characterized
by
a
wide
range
of
complications,
which
include
pulmonary
embolism,
thromboembolism
arterial
clot
formation,
arrhythmias,
cardiomyopathy,
multiorgan
failure,
more.
The
disease
caused
worldwide
pandemic,
despite
various
measures
such
as
social
distancing,
preventive
strategies,
therapeutic
approaches,
the
creation
vaccines,
novel
coronavirus
infection
(COVID-19)
still
hides
many
mysteries
for
scientific
community.
Oxidative
stress
been
suggested
play
an
essential
role
pathogenesis
COVID-19,
determining
free
radical
levels
patients
with
may
provide
insight
into
severity.
generation
abnormal
oxidants
under
COVID-19-induced
cytokine
storm
irreversible
oxidation
macromolecules
subsequent
damage
cells,
tissues,
organs.
Clinical
studies
have
shown
that
oxidative
initiates
endothelial
damage,
increases
risk
complications
post-COVID-19
or
long-COVID-19
cases.
This
review
describes
radicals
mediation
mitochondrial
dysfunction.
Cell Death Discovery,
Год журнала:
2025,
Номер
11(1)
Опубликована: Янв. 24, 2025
Abstract
Free
radicals,
characterized
by
the
presence
of
unpaired
electrons,
are
highly
reactive
species
that
play
a
significant
role
in
human
health.
These
molecules
can
be
generated
through
various
endogenous
processes,
such
as
mitochondrial
respiration
and
immune
cell
activation,
well
exogenous
sources,
including
radiation,
pollution,
smoking.
While
free
radicals
essential
for
certain
physiological
signaling
defense,
their
overproduction
disrupt
delicate
balance
between
oxidants
antioxidants,
leading
to
oxidative
stress.
Oxidative
stress
results
damage
critical
biomolecules
like
DNA,
proteins,
lipids,
contributing
pathogenesis
diseases.
Chronic
conditions
cancer,
cardiovascular
diseases,
neurodegenerative
disorders,
inflammatory
diseases
have
been
strongly
associated
with
harmful
effects
radicals.
This
review
provides
comprehensive
overview
characteristics
types
mechanisms
formation,
biological
impacts.
Additionally,
we
explore
natural
compounds
extracts
studied
antioxidant
properties,
offering
potential
therapeutic
avenues
managing
radical-induced
damage.
Future
research
directions
also
discussed
advance
our
understanding
treatment
radical-associated
Nutrients,
Год журнала:
2024,
Номер
16(16), С. 2587 - 2587
Опубликована: Авг. 6, 2024
Antioxidants
are
endogenous
and
exogenous
substances
with
the
ability
to
inhibit
oxidation
processes
by
interacting
reactive
oxygen
species
(ROS).
ROS,
in
turn,
small,
highly
capable
of
oxidizing
a
wide
range
molecules
human
body,
including
nucleic
acids,
proteins,
lipids,
carbohydrates,
even
small
inorganic
compounds.
The
overproduction
ROS
leads
oxidative
stress,
which
constitutes
significant
factor
contributing
development
disease,
not
only
markedly
diminishing
quality
life
but
also
representing
most
common
cause
death
developed
countries,
namely,
cardiovascular
disease
(CVD).
aim
this
review
is
demonstrate
effect
selected
antioxidants,
such
as
coenzyme
Q10
(CoQ10),
flavonoids,
carotenoids,
resveratrol,
well
introduce
new
antioxidant
therapies
utilizing
miRNA
nanoparticles,
reducing
incidence
progression
CVD.
In
addition,
context
aforementioned
diseases
will
be
considered.
This
emphasizes
pleiotropic
effects
benefits
stemming
from
presence
mentioned
organism,
leading
an
overall
reduction
risk,
coronary
heart
dyslipidaemia,
hypertension,
atherosclerosis,
myocardial
hypertrophy.
Frontiers in Cardiovascular Medicine,
Год журнала:
2024,
Номер
11
Опубликована: Фев. 2, 2024
Arterial
hypertension
represents
a
leading
cause
of
cardiovascular
morbidity
and
mortality
worldwide,
the
identification
effective
solutions
for
treating
early
stages
elevated
blood
pressure
(BP)
is
still
relevant
issue
risk
prevention.
The
pathophysiological
basis
occurrence
BP
onset
arterial
have
been
widely
studied
in
recent
years.
In
addition,
consistent
progress
development
novel,
powerful,
antihypertensive
drugs
their
appropriate
applications
controlling
increased
our
potential
successfully
managing
disease
states
characterized
by
abnormal
pressure.
However,
mechanisms
responsible
disruption
endogenous
contributing
to
maintenance
within
normal
range
are
yet
be
fully
clarified.
Recently,
evidence
has
shown
that
several
natural
antioxidants
containing
active
ingredients
originating
from
plant
extracts,
used
alone
or
combination,
may
represent
valid
solution
counteracting
hypertension.
particular,
there
show
enhance
viability
endothelial
cells
undergoing
oxidative
damage,
an
effect
could
play
crucial
role
events
accompanying
present
review
aims
reassess
stress
on
dysfunction
progression
covering
unmet
needs
treatment
such
diseases.
Healthcare,
Год журнала:
2024,
Номер
12(4), С. 416 - 416
Опубликована: Фев. 6, 2024
Obesity
has
become
a
global
health
concern,
with
its
prevalence
steadily
increasing
in
recent
decades.
It
is
associated
numerous
complications,
including
cardiovascular
diseases,
diabetes,
and
certain
types
of
cancer.
The
aetiology
obesity
multifactorial,
involving
genetic,
environmental,
lifestyle
factors.
In
years,
oxidative
stress
emerged
as
potential
contributor
to
related
metabolic
disorders.
Dietary
antioxidants,
which
can
counteract
stress,
have
gained
significant
attention
for
their
role
preventing
managing
obesity.
This
comprehensive
review
aims
explore
the
impact
dietary
antioxidants
on
dysregulations,
discussing
underlying
mechanisms
highlighting
therapeutic
implications.
Frontiers in Endocrinology,
Год журнала:
2024,
Номер
15
Опубликована: Июнь 11, 2024
Background
The
Oxidative
Balance
Score
(OBS),
which
quantifies
the
balance
between
antioxidants
and
pro-oxidants
influenced
by
diet
lifestyle,
is
crucial
given
oxidative
stress’s
significant
role
in
Chronic
Kidney
Disease
(CKD).
This
study
aims
to
determine
association
OBS
CKD
using
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
1999-2018.
Methods
We
analyzed
spanning
1999
2018.
was
constructed
a
detailed
array
of
20
factors,
including
dietary
nutrients
lifestyle
behaviors.
relationship
risk
evaluated
weighted
logistic
regression
models,
adjusted
for
potential
confounders,
with
generalized
additive
model
(GAM)
examining
non-linear
associations.
Subgroup
analyses
interaction
effects
across
diverse
demographic
clinical
groups,
along
sensitivity
analyses,
were
performed
validate
findings.
Results
Among
32,120
participants
analyzed,
4,786
identified
CKD.
Fully
analysis
revealed
that
each
unit
increase
associated
2%
reduction
prevalence
[OR:
0.98
(0.98–0.99),
P
<
0.001].
Higher
quartiles
significantly
correlated
decreased
[Q4
vs
.
Q1:
OR:
0.82
(0.68–0.98),
=
0.03;
trend
0.01].
GAM
smoothed
curve
fit
indicated
linear
Stratified
further
substantiated
inverse
prevalence.
Conclusions
Our
findings
NHANES
affirm
U.S.
population,
underscoring
optimizing
factors
managing
risk.
These
results
advocate
incorporating
considerations
into
prevention
treatment
strategies.
Pflügers Archiv - European Journal of Physiology,
Год журнала:
2023,
Номер
475(7), С. 835 - 844
Опубликована: Июнь 7, 2023
Abstract
Cigarette
smoking
is
the
most
important
avoidable
cardiovascular
risk
factor.
It
causes
endothelial
dysfunction
and
atherosclerosis
increases
of
its
severe
clinical
complications
like
coronary
artery
disease,
myocardial
infarction,
stroke,
peripheral
disease.
Several
next
-
generation
tobacco
nicotine
products
have
been
developed
to
decrease
some
deleterious
effects
regular
smoking.
This
review
article
summarizes
recent
findings
about
impact
cigarette
on
dysfunction.
Both
lead
impaired
function.
Molecular
mechanisms
oxidative
stress,
reduced
nitric
oxide
availability,
inflammation,
increased
monocyte
adhesion,
cytotoxic
smoke
are
highlighted.
The
potential
short-
long-term
exposure
development
implications
for
diseases
discussed.
