Diagnostic methods/parameters to monitor peri‐implant conditions

Periodontology 2000, Год журнала: 2024, Номер 95(1), С. 20 - 39

Опубликована: Июнь 1, 2024

The diagnostic accuracy of clinical parameters, including visual inspection and probing to monitor peri-implant conditions, has been regarded with skepticism. Scientific evidence pointed out that primary tools (chairside) seem be highly specific, while their sensitivity is lower compared use in monitoring periodontal stability. Nonetheless, given the association between pocket depth at teeth implant sites aerobic/anaerobic nature microbiome, it seems plausible for indicative disease progression or tissue In addition, understanding inflammatory diseases, reasonable advocate bleeding, erythema, ulceration, suppuration might reliable indicators pathology. Nevertheless, single spots bleeding on may not reflect disease, since implants are prone exhibit related force. On other side, smokers lacks owing decreased angiogenic activity. Hence, dichotomous scales general population, contrast indices feature profuseness time after probing, lead false positive diagnoses. definitive distinction mucositis peri-implantitis, though, relies upon radiographic progressive bone loss can assessed by means two- three-dimensional methods. Accordingly, objective this review evaluate existing parameters/methods conditions.

Язык: Английский

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Coronally advanced flap versus tunnel technique for the treatment of peri‐implant soft tissue dehiscences with the connective tissue graft: A randomized, controlled clinical trial

Journal Of Clinical Periodontology, Год журнала: 2023, Номер 50(7), С. 980 - 995

Опубликована: Март 20, 2023

To evaluate the efficacy of coronally advanced flap (CAF) versus tunnel technique (TUN) in covering isolated mid-facial peri-implant soft tissue dehiscences (PSTDs).Twenty-eight participants presenting with non-molar implants exhibiting PSTDs were enrolled and randomized to receive either CAF or TUN, both a connective graft (CTG). The primary outcome study was percentage mean PSTD coverage at 12 months. Secondary endpoints included frequency complete coverage, changes keratinized mucosa width (KMW) horizontal mucosal thickness (MT), as assessed transgingival probing, 3D optical scanning ultrasonography, professional aesthetic evaluation patient-reported measures (PROMs).At months, TUN groups 90.23% 59.76%, respectively (p = .03). CAF-treated sites showed substantially higher .07), together significantly greater gain KMW .01), increase MT .02), volumetric < .01) outcomes .01). Both interventions an improvement aesthetics reduction anxiety related appearance implant compared baseline, group obtaining scores .03 for PROMs).CAF + CTG resulted superior outcomes, MT, better PROMs than treatment (ClinicalTrials.gov NCT03498911).

Язык: Английский

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Doppler ultrasonographic evaluation of tissue revascularization following connective tissue graft at implant sites

Journal Of Clinical Periodontology, Год журнала: 2023, Номер unknown

Опубликована: Окт. 20, 2023

Abstract Aim To assess the Doppler ultrasonographic tissue perfusion at dental implant sites augmented with connective graft (CTG) using coronally advanced flap (CAF) or tunnel technique (TUN). Materials and Methods Twenty‐eight patients presenting isolated healthy peri‐implant soft‐tissue dehiscence (PSTD) were included in this randomized clinical trial. PSTDs treated either CAF + CTG TUN CTG. Ultrasound scans taken baseline, 1 week, month, 6 months 12 months. Tissue mid‐facial, mesial distal aspects of was assessed by colour velocity (CDV) power imaging (PDI). Early vascularization week month evaluated via dynamic measurements (DTPMs), including flow intensity (FI), mean relief (pRI) perfused area (pA). Results Regression analysis did not reveal significant differences terms mid‐facial CDV PDI changes between over ( p > .05), while two groups observed interproximal areas < .001 for both changes). Higher early DTPMs TUN‐treated FI = .027) .024) pRI .031) compared CAF‐treated week. Assessment direction showed that mainly occurred from towards implant/bone. outcomes found to be associated 12‐month PSTD coverage mucosal thickness gain. Conclusions ultrasonography shows occurring The main sites, volumetric

Язык: Английский

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A Mapping Review of the Pathogenesis of Peri-Implantitis: The Biofilm-Mediated Inflammation and Bone Dysregulation (BIND) Hypothesis

Cells, Год журнала: 2024, Номер 13(4), С. 315 - 315

Опубликована: Фев. 8, 2024

This mapping review highlights the need for a new paradigm in understanding of peri-implantitis pathogenesis. The biofilm-mediated inflammation and bone dysregulation (BIND) hypothesis is proposed, focusing on relationship between biofilm, inflammation, biology. close interactions immune cells are discussed, with multiple stable states likely existing clinically observable definitions peri-implant health peri-implantitis. framework presented aims to explain transition from disease as staged incremental process, where factors contribute distinct steps towards tipping point manifested clinically. These might be reached different ways patients may constitute highly individualised paths. Notably, affecting underlying biology identified pathogenesis peri-implantitis, highlighting that disruptions host–microbe homeostasis at implant–mucosa interface not sole factor. An improved will allow intervention levels personalised treatment approach. Further research areas identified, such use novel biomarkers detect changes macrophage polarisation activation status, turnover.

Язык: Английский

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Revealing leukocyte populations in human peri-implantitis and periodontitis using flow cytometry

Clinical Oral Investigations, Год журнала: 2023, Номер 27(9), С. 5499 - 5508

Опубликована: Июль 25, 2023

Язык: Английский

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Echo‐intensity characterization at implant sites and novel diagnostic ultrasonographic markers for peri‐implantitis

Journal Of Clinical Periodontology, Год журнала: 2024, Номер unknown

Опубликована: Апрель 1, 2024

Abstract Aim To apply high‐frequency ultrasound (HFUS) echo intensity for characterizing peri‐implant tissues at healthy and diseased sites to investigate the possible ultrasonographic markers of health versus disease. Materials Methods Sixty patients presenting 60 implants diagnosed as ( N = 30) peri‐implantitis were assessed with HFUS. HFUS scans imported into a software where first‐order greyscale outcomes [i.e., mean (EI)] second‐order assessed. Other interest involved vertical extension hypoechoic supracrestal area (HSA), soft‐tissue (STA) buccal bone dehiscence (BBD), among others. Results EI values obtained from soft tissue 122.9 ± 19.7 107.9 24.7 grey levels (GL); p .02, respectively. All showed appearance an HSA that was not present in (area under curve 1). The proportion HSA/STA 37.9% 14.8%. Regression analysis significantly different between (odds ratio 0.97 [95% confidence interval: 0.94–0.99], .019). Conclusions characterization shows significant difference sites. presence/absence may be valid diagnostic discriminate status.

Язык: Английский

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How do the dimensions of peri‐implant mucosa affect marginal bone loss in equicrestal and subcrestal position of implants? A 1‐year clinical trial

Clinical Implant Dentistry and Related Research, Год журнала: 2024, Номер 26(2), С. 442 - 456

Опубликована: Янв. 28, 2024

Abstract Introduction There is evidence that the apico‐coronal implant position and mucosal phenotype can affect extent of peri‐implant bone loss. This clinical trial analyzes remodeling marginal loss occur around conical‐connection implants placed equicrestally subcrestally, assessing effect soft‐tissue phenotype. Methods Fifty‐one patients received 56 distinct diameters (3.5 mm Ø n = 6; 4.3 41; 5 9) in posterior part maxilla or mandible. The were equicrestally, 1 subcrestally >1 depending on initial supracrestal tissue height (STH). After 3 months non‐submerged healing, single metal‐ceramic screw‐retained implant‐supported crowns placed. Longitudinal measurements STH, thickness keratinized mucosa width (KMW) made at time placement (T0), crown (T1), after (T2) 6 (T3) prosthetic loading. At each these points, a radiographic evaluation was also performed. Results STH significantly greater for than those subcrestally. 12 follow‐up, very significant ( p < 0.001) KMW observed, addition to 0.08 ± 0.1, 0.15 0.2, 0.14 0.2 groups respectively. multiple linear regression, found depend primarily β −0.43), while being affected by 0.32) diameter −0.28). Conclusions Marginal may be influenced with respect crest, as well KMW, diameter. However, more well‐controlled studies are needed verify above‐mentioned findings different designs connections.

Язык: Английский

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Soft tissue elasticity at teeth and implant sites. A novel outcome measure of the soft tissue phenotype

Journal of Periodontal Research, Год журнала: 2024, Номер unknown

Опубликована: Июнь 5, 2024

To assess ultrasonographic tissue elasticity at teeth and implant sites its variation after peri-implant soft augmentation with a connective graft (CTG).

Язык: Английский

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Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures

Journal of Periodontal Research, Год журнала: 2025, Номер unknown

Опубликована: Янв. 22, 2025

ABSTRACT Aim To assess tissue perfusion changes and wound healing biomarker levels after root coverage procedures with coronally advanced flap in combination the cross‐linked xenogeneic collagen matrix (CCMX), loaded either a placebo or recombinant human platelet‐derived growth factor‐BB (rhPDGF). Methods This study was designed as secondary analysis from previously published clinical trial, it assessed over 6 months around multiple gingival recession defects, treated CCMX alone (control) + rhPDGF (test). High frequency Doppler ultrasonography (HFUS) scans were obtained at sites of interest baseline, 2 weeks, 3 months, surgery. Dynamic measurements (DTPMs) performed midfacial, interproximal, transverse aspects teeth by an operator, blinded to treatment allocation, using software package. The expression different biomarkers crevicular fluid also assessed. Results regression analyses showed similar between two groups throughout majority months. DTPMs weeks test group have significantly higher relief intensity (pRI, p < 0.001), mean perfused area (pA, blood flow (FI , = 0.021), total tot 0.021) graft region (ROI) compared control sites. exhibited greater pA ( 0.033) “blue” blue meaning away transducer, 0.035) level At FI directly correlated final 0.008) complete 0.003). direct correlation volume gain 0.031 for both parameters). GT early (pA ) flap. expressions IL‐1β, PDFG‐BB, VEGF 1‐week PDGF‐BB that associated time recovery. Conclusions HFUS allowed exquisite assessment occurring entire surgical reconstructive regions within graft. Sites DTPMs, primarily ROIs 2‐week timepoint augmented saline. Early associations PROMs outcomes. Trial Registration: ClinicalTrials.gov : NCT04462237

Язык: Английский

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Digital technology-enhanced reconstruction and rehabilitation following mandible fibular flap grafting with implants: a case report

Frontiers in Dental Medicine, Год журнала: 2025, Номер 6

Опубликована: Март 5, 2025

In this paper, we report a case of missing posterior teeth after mandibular fibular flap grafting and implant restoration by means digital restorative process, in the hope that application technology will help patient to comfortably establish an adapted occlusal relationship. A 29-year-old male developed left ameloblastoma measuring 35 mm × 25 mm, which did not invade surrounding bone tissue, submandibular gland or lymph nodes. After resection 85 segment, was reconstructed using gastrocnemius transfer. He then referred our institution for postoperative dental restoration. The process incorporated various technologies including facebow, intraoral scanner, extraoral facial CAD/CAM systems. Following 1 year post-implantation, received second-stage implantation alongside autologous dermal allograft (ADM) transplantation; subsequently, temporary prosthesis fabricated while employing electronic articulator accurately transfer relationships before finalizing with permanent restorations. integration throughout enhanced both precision comfort. This study offers innovative efficient clinical approach addressing dentition defect following reconstruction via advanced methodologies.

Язык: Английский

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