Dynamic evolutionary interplay between ontogenetic skull patterning and whole-head integration
Nature Ecology & Evolution,
Год журнала:
2024,
Номер
8(3), С. 536 - 551
Опубликована: Янв. 10, 2024
Язык: Английский
Echolocation and dietary adaptations mediate brain-endocast covariation in bats
iScience,
Год журнала:
2025,
Номер
28(4), С. 112159 - 112159
Опубликована: Март 5, 2025
Bats
exhibit
remarkable
ecological
diversity,
reflected
in
different
species'
sensory,
cognitive
and
behavioral
ecology.
Bat
brain
volume
has
been
linked
to
powered
flight,
laryngeal
echolocation,
dietary
transitions.
Given
the
developmental
trajectories
functional
demands
skull
share,
bat
skull-brain
complex
represents
a
unique
means
better
understand
evolutionary
processes
trade-offs.
We
assessed
brain-endocast
correspondence
across
bats,
considering
whether
changes
reflect
adaptations.
demonstrate
that
estimates
of
from
both
methods
showed
similar
allometric
trajectories,
apart
those
for
cerebral
cortex.
Our
results
reveal
significant
effect
diet
echolocation
on
cortex
olfactory
bulbs,
respectively.
suggest
shifts
bulbs
indicate
an
trade-off
between
olfaction
echolocation.
study
offers
perspective
future
comparative
neuroanatomical
studies
involving
extinct
living
species
museum
collections.
Язык: Английский
A brain-wide analysis maps structural evolution to distinct anatomical module
eLife,
Год журнала:
2023,
Номер
12
Опубликована: Июль 27, 2023
The
vertebrate
brain
is
highly
conserved
topologically,
but
less
known
about
neuroanatomical
variation
between
individual
regions.
Neuroanatomical
at
the
regional
level
hypothesized
to
provide
functional
expansion,
building
upon
ancestral
anatomy
needed
for
basic
functions.
Classically,
animal
models
used
study
evolution
have
lacked
tools
detailed
anatomical
analysis
that
are
widely
in
zebrafish
and
mice,
presenting
a
barrier
studying
fine
scales.
In
this
study,
we
sought
investigate
of
using
single
species
fish
consisting
divergent
surface
cave
morphs,
permits
genetic
testing
volume
shape
across
entire
brain.
We
generated
high-resolution
atlas
blind
Mexican
cavefish
Astyanax
mexicanus
coupled
with
automated
computational
directly
assess
variability
region
all
populations.
measured
every
grossly
defined
assessed
correlations
regions
fish,
cavefish,
×
F
2
hybrids,
whose
phenotypes
span
range
cave.
find
dorsal
contracted,
while
ventral
expanded,
hybrid
data
providing
support
developmental
constraint
along
dorsal-ventral
axis.
Furthermore,
these
relationships
show
similar
patterns
both
shape,
suggesting
captured
by
two
parameters
could
be
driven
mechanisms.
Together,
demonstrate
A.
powerful
system
functionally
determining
principles
will
permit
how
genes
influence
early
patterning
events
drive
brain-wide
evolution.
Язык: Английский
Evolution of the essential gene MN1 during the macroevolutionary transition toward patterning the vertebrate hindbrain
Proceedings of the National Academy of Sciences,
Год журнала:
2025,
Номер
122(22)
Опубликована: Май 27, 2025
The
tight
link
between
brain
and
skull
formation
is
a
fundamental
aspect
of
vertebrate
evolution
embryogenesis.
Their
developmental
synchronization
essential
for
structural
functional
integration.
shape
coevolution
evident
along
the
phylogeny;
however,
genetic
basis
underlying
their
close
evolutionary
relationship
remains
little
explored.
Here,
we
reveal
function
MN1
gene
that
was
previously
found
to
be
associated
with
significant
variation
in
mouse
cranial
bones.
We
show
evolved
from
an
ancestral
deuterostome
sequence.
In
vertebrates,
structure,
synteny,
spatiotemporal
expression
pattern
are
remarkably
conserved,
indicating
carries
out
core
function.
Using
newly
generated
knock-out
model,
demonstrate
vivo
Mn1
integrated
into
ancient
molecular
machinery
controls
Cyp26
genes
developing
hindbrain,
thereby
tuning
retinoic
acid
levels
patterning
central
nervous
system.
This
study
thus
showcases
emergence
novel
sequence
its
role
generating
macroevolutionary
innovation.
data
expand
our
knowledge
codevelopment
highlight
this
regulatory
loop
craniofacial
human
syndromes.
Язык: Английский
A proxy for brain‐to‐endocranial cavity index in non‐neornithean dinosaurs and other extinct archosaurs
The Journal of Comparative Neurology,
Год журнала:
2024,
Номер
532(3)
Опубликована: Март 1, 2024
Abstract
Although
the
brain
fills
nearly
entire
cranial
cavity
in
birds,
it
can
occupy
a
small
portion
of
crocodilians.
The
lack
data
regarding
volumetric
correspondence
between
and
hampers
thorough
assessments
degree
encephalization
non‐neornithean
dinosaurs
other
extinct
archosaurs
and,
consequently,
informed
inferences
their
cognitive
capacities.
Existing
suggest
that,
across
extant
archosaurs,
endocranial
doming
volume
intracranial
nonneural
components
are
inversely
related.
We
build
upon
this
information
to
develop
an
equation
relating
these
two
anatomical
features
archosaurs.
rely
on
measurements
endocast
brain‐to‐endocranial
(BEC)
index
relatives
dinosaurs,
namely,
crurotarsans
Caiman
crocodilus
,
Crocodylus
niloticus
porosus
;
paleognaths
Struthio
camelus
Apteryx
mantelli
fowl
Macrocephalon
maleo
Gallus
gallus
Meleagris
gallopavo
Phasianus
colchicus
Anas
platyrhynchos
.
Applying
representative
endocasts
from
major
clades
we
found
that
BEC
varies
about
0.6
ceratopsians
thyreophorans
around
0.7
ornithopods,
pachycephalosaurians,
sauropods,
theropods.
We,
therefore,
warn
against
use
catch‐all
value,
like
0.5,
instead
encourage
refinement
adoption
Язык: Английский
Covariation of brain and skull shapes as a model to understand the role of crosstalk in development and evolution
Evolution & Development,
Год журнала:
2022,
Номер
25(1), С. 85 - 102
Опубликована: Ноя. 14, 2022
Abstract
Covariation
among
discrete
phenotypes
can
arise
due
to
selection
for
shared
functions,
and/or
genetic
and
developmental
underpinnings.
The
consequences
of
such
phenotypic
integration
are
far‐reaching
act
either
facilitate
or
limit
morphological
variation.
vertebrate
brain
is
known
as
an
“organizer”
craniofacial
development,
secreting
morphogens
that
affect
the
shape
growing
neurocranium,
consistent
with
roles
pleiotropy
in
brain–neurocranium
covariation.
Here,
we
test
this
hypothesis
cichlid
fishes
by
first
examining
degree
between
neurocranium
using
three‐dimensional
geometric
morphometrics
F
5
hybrid
population,
then
genetically
mapping
trait
covariation
quantitative
loci
(QTL)
analysis.
We
observe
associations
a
pattern
holds
even
when
assess
constituent
parts
neurocranium:
rostrum
braincase.
also
recover
robust
signals
both
hard‐
soft‐tissue
traits
identify
genomic
region
where
QTL
braincase
overlap,
implicating
role
patterning
Fine
overlapping
identifies
candidate
gene,
notch1a
,
which
be
involved
skeletal
neural
tissues
during
development.
Taken
together,
these
data
offer
covariation,
well
potential
mechanism
behavioral
shifts
may
simultaneously
drive
rapid
change
neuroanatomy
morphology.
Язык: Английский
The professional interactions between speech language therapist and dentist
Exploration of Medicine,
Год журнала:
2024,
Номер
unknown, С. 434 - 443
Опубликована: Июнь 25, 2024
Aim:
This
study
investigates
the
collaborative
efforts
between
speech
language
therapists
and
dentists
to
address
challenges
faced
by
patients
with
concurrent
dental
issues.
It
underscores
importance
of
understanding
complex
interactions
within
craniofacial
system
its
implications
for
both
oral
health
communication
abilities.
Methods:
A
questionnaire-based
research
was
conducted
involving
dentists,
using
Google
Forms
as
medium
data
collection.
disseminated
through
professional
networks,
where
practitioners
provided
information
on
their
demographics,
practices
collaboration,
perceived
advantages
such
interdisciplinary
work.
All
ethical
standards
were
adhered
to,
ensuring
confidentiality
informed
consent
participants.
Results:
The
findings
indicate
that
often
see
first
patient
visits
beyond
recommended
ages
primarily
existing
conditions,
deviating
from
preventive
norms.
About
half
communicate
monthly
therapists,
revealing
gaps
in
early
care
collaboration.
Speech
focus
disorders
orofacial
myofunctional
(SMOF),
37%
collaborating
frequently
dentists.
interaction
highlights
potential
enhanced
outcomes
cooperation.
Despite
these
challenges,
groups
acknowledged
benefits
efforts.
Conclusions:
partnership
represents
a
vital
area
healthcare,
aimed
at
tackling
issues
multidisciplinary
approach.
Although
obstacles
collaboration
identified,
positive
observed
partnerships
emphasize
developing
unified
framework
improve
integrated
healthcare
delivery
future.
Язык: Английский
Covariation of Skull and Brain Morphology in Domestic Dogs
The Journal of Comparative Neurology,
Год журнала:
2024,
Номер
532(9)
Опубликована: Сен. 1, 2024
ABSTRACT
Despite
their
distinct
embryonic
origins,
the
skull
and
brain
are
highly
integrated.
Understanding
covariation
between
can
shed
light
on
anatomical,
cognitive,
behavioral
traits
in
extant
extinct
species.
Domestic
dogs
offer
a
unique
opportunity
to
investigate
skull–brain
due
diverse
morphologies
neural
anatomy.
To
assess
this
question,
we
examined
T
2‐weighted
MRI
studies
of
62
from
33
breeds,
plus
an
additional
17
mixed
or
unknown
breeds.
Scans
were
opportunistically
collected
veterinary
teaching
hospital
that
referred
for
neurological
examination
but
did
not
have
grossly
observable
structural
abnormalities.
As
neurocrania
become
broader
shorter,
there
is
significant
decrease
gray
matter
volume
right
olfactory
bulb,
frontal
cortex,
marginal
gyrus,
cerebellum.
On
other
hand,
as
narrower
longer,
temporal
amygdala,
hypothalamus,
hippocampus,
periaqueductal
gray,
cerebellum,
brainstem.
Selective
breeding
specific
shapes
may
impact
canine
anatomy
function.
Язык: Английский
The evolution and genetic basis of a functionally critical skull bone, the parasphenoid, among Lake Malawi cichlids
Evolutionary Journal of the Linnean Society,
Год журнала:
2024,
Номер
3(1)
Опубликована: Янв. 1, 2024
Abstract
Adaptive
radiation,
whereby
a
clade
pairs
rapid
speciation
with
phenotypic
evolution,
can
result
in
an
uneven
distribution
of
biodiversity
across
the
Metazoan
tree.
The
cichlid
fishes
East
Africa
have
undergone
multiple
adaptive
radiations
within
major
rift
lakes.
Cichlid
are
marked
by
divergence
distinct
habitat
gradients
producing
many
morphological
and
behavioural
adaptations.
Here,
we
characterize
shape
parasphenoid,
bone
neurocranium
that
dissipates
forces
generated
during
feeding.
We
examine
Tropheops,
group
has
transitioned
between
deep
shallow
habitats
times,
to
habitat-specific
differences
parasphenoid
shape.
find
depth
length
Tropheops
residing
each
habitat,
variation
may
impact
ability
cranium
resist
force.
next
use
hybrid
cross
two
species
differ
shape,
Labeotropheus
genetic
basis
these
differences.
perform
mapping
identify
genomic
regions
responsible
for
These
implicated
other
functional
traits
including
oral
jaws
neurocranium,
indicating
landscape
evolution
be
limited
few
loci
broad
effects.
Repurposing
same
gene(s)
via
regulatory
sufficient
selection
drive
transitions
important
incipient
stages
radiations.
Язык: Английский
Dinosaur palaeoneurology: an evolving science
Biology Letters,
Год журнала:
2024,
Номер
20(12)
Опубликована: Дек. 1, 2024
Our
fascination
with
dinosaur
brains
and
their
capabilities
essentially
began
the
first
discovery.
The
history
of
this
study
is
a
useful
reflection
palaeoneurology
as
whole
its
relationship
to
more
inclusive
evolutionary
neuroscience.
I
argue
that
imbued
high
heuristic
potential,
but
one
whose
realization
requires
overcoming
certain
constraints.
These
constraints
include
need
for
stable
phylogenetic
framework,
methods
efficient
precise
endocast
construction,
fossil
researchers
who
are
steeped
in
neuroscience
perspective.
progress
has
already
been
made
these
areas
sets
stage
mature
palaeoneurology—not
only
capable
being
informed
by
discoveries
drives
such
discoveries.
draw
from
work
on
size,
shape,
behavioural
correlates
developmental
role
brain
outline
current
advances
palaeoneurology.
My
examples
largely
taken
theropods
centre
questions
related
origin
birds
unique
locomotory
capabilities.
hope,
however,
exemplify
potential
other
groups,
utilizing
dinosaur–bird
lineage
parallel
model
par
mammals
studying
encephalization.
Язык: Английский