Combine with RNA-seq Reveals the Effect of Melatonin in the Synthesis of Melanin in Primary Melanocytes of Silky Fowls Black-Bone Chicken DOI Open Access

Ting Yang,

Lingling Qiu, Shihao Chen

и другие.

Genes, Год журнала: 2023, Номер 14(8), С. 1648 - 1648

Опубликована: Авг. 18, 2023

(1) Background: It was found that the melanin of black-bone chicken has various effects such as scavenging DPPH free radicals and anti-oxidation, synthesis is affected by factors including hormones. In addition, several studies have melatonin affects melanoma cell melanin, which not been reported in primary melanocytes; so, relevant were conducted. (2) Methods: this study, melanocytes isolated characterized, then treated with different concentrations to investigate on terms synthesis-related genes, content, tyrosinase activity, combined RNA seq detect change gene expression level after treatment. (3) Results: We characterized melanocytes, indirect immunofluorescence assay results showed positive melanocyte marker genes. RT-qPCR decreased reduced content activity group. A total 1703 differentially expressed genes screened RNA-seq, KEGG results, signaling pathway associated synthesis, mTOR enriched. (4) Conclusions: Melatonin could decrease melanocytes.

Язык: Английский

Vasoactive intestinal peptide (VIP) operates as a negative regulator of human hair follicle pigmentation ex vivo DOI
Tatiana Gomez Gomez, Jérémy Chéret, Barbara Bedogni

и другие.

Journal of Investigative Dermatology, Год журнала: 2024, Номер unknown

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

0
The influence of phototherapy on circadian melatonin and sleep regulation and potential benefits of these pathways in the management of vitiligo: a narrative review DOI
Ellen M. S. Xerfan, Anamaria S. Facina, Jane Tomimori

и другие.

Archives of Dermatological Research, Год журнала: 2024, Номер 316(9)

Опубликована: Сен. 21, 2024

Язык: Английский

Процитировано

0
Topical melatonin: wake up looking younger…? DOI
Ralf Paus, Sofia M. Perez

British Journal of Dermatology, Год журнала: 2024, Номер unknown

Опубликована: Окт. 9, 2024

Topical melatonin applied over many days and weeks, which might even reduce dermatitis, erythema sunburn, could be a promising start in the lifelong battle to impede and, ideally, reverse intrinsic extrinsic human skin ageing.

Язык: Английский

Процитировано

0
Combine with RNA-seq Reveals the Effect of Melatonin in the Synthesis of Melanin in Primary Melanocytes of Silky Fowls Black-Bone Chicken DOI Open Access

Ting Yang,

Lingling Qiu, Shihao Chen

и другие.

Genes, Год журнала: 2023, Номер 14(8), С. 1648 - 1648

Опубликована: Авг. 18, 2023

(1) Background: It was found that the melanin of black-bone chicken has various effects such as scavenging DPPH free radicals and anti-oxidation, synthesis is affected by factors including hormones. In addition, several studies have melatonin affects melanoma cell melanin, which not been reported in primary melanocytes; so, relevant were conducted. (2) Methods: this study, melanocytes isolated characterized, then treated with different concentrations to investigate on terms synthesis-related genes, content, tyrosinase activity, combined RNA seq detect change gene expression level after treatment. (3) Results: We characterized melanocytes, indirect immunofluorescence assay results showed positive melanocyte marker genes. RT-qPCR decreased reduced content activity group. A total 1703 differentially expressed genes screened RNA-seq, KEGG results, signaling pathway associated synthesis, mTOR enriched. (4) Conclusions: Melatonin could decrease melanocytes.

Язык: Английский

Процитировано

0