Damage and elimination of soil and water antibiotic and heavy metal pollution caused by livestock husbandry

Environmental Research, Год журнала: 2022, Номер 215, С. 114188 - 114188

Опубликована: Авг. 27, 2022

Язык: Английский

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Co-selection for antibiotic resistance by environmental contaminants

npj Antimicrobials and Resistance, Год журнала: 2024, Номер 2(1)

Опубликована: Апрель 1, 2024

The environment is increasingly recognised as a hotspot for the selection and dissemination of antibiotic resistant bacteria resistance genes. These can be selected by antibiotics non-antibiotic agents (such metals biocides), with evidence to support this well established observational experimental studies. However, there emerging suggest that plant protection products herbicides), drugs chemotherapeutic agents), also co-select resistance. This review aims provide an overview four classes (metals, biocides, products, drugs) how they may resistance, particular focus on environment. It identify key knowledge gaps should addressed in future work, better understand these potential co-selective agents.

Язык: Английский

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Phytoremediation as an Effective Remedy for Removing Trace Elements from Ecosystems

Plants, Год журнала: 2023, Номер 12(8), С. 1653 - 1653

Опубликована: Апрель 14, 2023

The pollution of soil by trace elements is a global problem. Conventional methods remediation are often inapplicable, so it necessary to search intensively for innovative and environment-friendly techniques cleaning up ecosystems, such as phytoremediation. Basic research methods, their strengths weaknesses, the effects microorganisms on metallophytes plant endophytes resistant (TEs) were summarised described in this manuscript. Prospectively, bio-combined phytoremediation with appears be an ideal, economically viable environmentally sound solution. novelty work description potential “green roofs” contribute capture accumulation many metal-bearing suspended dust other toxic compounds resulting from anthropopressure. Attention was drawn great using less contaminated soils located along traffic routes urban parks green spaces. It also focused supportive treatments genetic engineering, sorbents, phytohormones, microbiota, microalgae or nanoparticles highlighted important role energy crops Perceptions different continents presented, new international perspectives presented. Further development requires much more funding increased interdisciplinary direction.

Язык: Английский

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Metal tolerance mechanisms in plants and microbe-mediated bioremediation

Environmental Research, Год журнала: 2023, Номер 222, С. 115413 - 115413

Опубликована: Фев. 1, 2023

Язык: Английский

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Unravelling the mechanisms of antibiotic and heavy metal resistance co-selection in environmental bacteria

FEMS Microbiology Reviews, Год журнала: 2024, Номер 48(4)

Опубликована: Июнь 19, 2024

Abstract The co-selective pressure of heavy metals is a contributor to the dissemination and persistence antibiotic resistance genes in environmental reservoirs. overlapping range metal contamination similarities their mechanisms point an intertwined evolutionary history. Metal are known be genetically linked genes, with plasmids, transposons, integrons involved assembly horizontal transfer elements. Models co-selection between antibiotics have been proposed, however, molecular aspects these phenomena many cases not defined or quantified importance specific metals, environments, bacterial taxa, mobile genetic elements, other abiotic biotic conditions clear. Co-resistance often suggested as dominant mechanism, but interpretations beset correlational bias. Proof principle examples cross-resistance co-regulation has described more in-depth characterizations needed, using methodologies that confirm functional expression connect hosts. Here, we comprehensively evaluate recent evidence for different models from pure culture metagenomic studies contexts highlight outstanding questions.

Язык: Английский

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Holistic One Health Surveillance Framework: Synergizing Environmental, Animal, and Human Determinants for Enhanced Infectious Disease Management

ACS Infectious Diseases, Год журнала: 2024, Номер 10(3), С. 808 - 826

Опубликована: Фев. 28, 2024

Recent pandemics, including the COVID-19 outbreak, have brought up growing concerns about transmission of zoonotic diseases from animals to humans. This highlights requirement for a novel approach discern and address escalating health threats. The One Health paradigm has been developed as responsive strategy confront forthcoming outbreaks through early warning, highlighting interconnectedness humans, animals, their environment. system employs several innovative methods such use advanced technology, global collaboration, data-driven decision-making come with an extraordinary solution improving worldwide disease responses. Review deliberates environmental, animal, human factors that influence risk, analyzes challenges advantages inherent in using surveillance system, demonstrates how these can be empowered by Big Data Artificial Intelligence. Holistic Surveillance Framework presented herein holds potential revolutionize our capacity monitor, understand, mitigate impact infectious on populations.

Язык: Английский

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Climate warming, environmental degradation and pollution as drivers of antibiotic resistance

Environmental Pollution, Год журнала: 2024, Номер 346, С. 123649 - 123649

Опубликована: Фев. 23, 2024

Язык: Английский

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Vancomycin Resistance in Enterococcus and Staphylococcus aureus

Microorganisms, Год журнала: 2022, Номер 11(1), С. 24 - 24

Опубликована: Дек. 21, 2022

Enterococcus faecalis, faecium and Staphylococcus aureus are both common commensals major opportunistic human pathogens. In recent decades, these bacteria have acquired broad resistance to several classes of antibiotics, including commonly employed glycopeptides. Exemplified by vancomycin, glycopeptide is mediated through intrinsic gene mutations, and/or transferrable van cassette-carrying mobile genetic elements. Here, this review will discuss the epidemiology vancomycin-resistant S. in healthcare, community, agricultural settings, explore vancomycin context non-van development provide insights into alternative therapeutic approaches aimed at treating drug-resistant infections.

Язык: Английский

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Heavy metal co-resistance with antibiotics amongst bacteria isolates from an open dumpsite soil

Heliyon, Год журнала: 2023, Номер 9(2), С. e13457 - e13457

Опубликована: Фев. 1, 2023

Heavy metal co-resistance with antibiotics appears to be synergistic in bacterial isolates via similar mechanisms. This synergy has the potential amplify resistance genes environment which can transferred into clinical settings. The aim of this study was assess heavy metals bacteria from dumpsite addition physicochemical analysis. Sample collection, analysis, and enumeration total heterotrophic counts (THBC) were all carried out using standard existing protocols. Identified subjected sensitivity test Kirby Bauer disc diffusion technique resulting multidrug resistant (MDR) tolerance agar dilution increasing concentrations (50, 100, 150, 200 250 μg/ml) our metals. THBC ranged 6.68 7.92 × 105 cfu/g. Out 20 sensitivity, 50% (n = 10) showed multiple drug these B. subtilis, cereus, C. freundii, P. aeruginosa, Enterobacter sp, E. coli 5). At lowest concentration (50 μg/ml), MDR tolerated metals, but at μg/ml, apart cadmium lead, 100% sensitive chromium, vanadium cobalt. control isolate only cobalt chromium 50 other level shown by is a call for concern.

Язык: Английский

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A Retrospection on Mercury Contamination, Bioaccumulation, and Toxicity in Diverse Environments: Current Insights and Future Prospects

Sustainability, Год журнала: 2023, Номер 15(18), С. 13292 - 13292

Опубликована: Сен. 5, 2023

Owing to various industrial applications of mercury (Hg), its release into the environment at high concentration is becoming a great threat living organisms on global scale. Human exposure Hg greatly correlated with contamination in food chain through cereal crops and sea foods. Since non-essential component does not possess biological role exhibits carcinogenic genotoxic behaviour, biomonitoring focus biomagnification higher animals plants need hour. This review traces plausible relationship between concentration, chemical form, exposure, bioavailability, bioaccumulation, distribution, ecotoxicology. The toxicity molecular mechanisms, oxidative stress (OS), protein alteration, genomic change, enzymatic disruptions are discussed. In addition, this also elaborates advanced strategies for reducing such as algal phytoremediation, biochar application, catalytical oxidation, immobilization. Furthermore, there challenges overcome future perspectives considering concentrations, biomarkers, identification nature exposures recommended.

Язык: Английский

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