Asian Journal of Chemistry,
Год журнала:
2024,
Номер
36(3), С. 531 - 542
Опубликована: Фев. 28, 2024
The
release
of
metals
into
the
environment
raises
serious
concerns
about
their
harmful
effects
on
both
wildlife
and
human
health.
biosphere
is
experiencing
with
pervasive
presence
heavy
metal
pollutants
such
as
arsenic
(As),
cadmium
(Cd),
mercury
(Hg),
lead
(Pb),
chromium
(Cr),
copper
(Cu)
nickel
(Ni),
which
pose
significant
environmental
challenges.
While
certain
are
essential
for
regulating
fundamental
metabolic
processes
upholding
overall
physiology
microorganisms,
excessive
exposure
to
can
be
detrimental
survival
function.
As
a
result
remarkable
adaptability,
particularly
bacteria
Pseudomonas
fluorescens,
Escherichia
coli,
Serratia
marcescens,
Bacillus
cereus
Alcaligenes
sp.,
have
evolved
sophisticated
defence
mechanisms
combat
stress
caused
by
metals.
One
process
creation
metal-binding
proteins
(MBPs),
may
bind
sequester
metals,
thus
significantly
lowering
toxicity
in
bacteria.
Metalloproteomics,
subfield
metallomics,
focuses
discovery
characterization
(MBPs)
metal-resistant
bacteria,
resulting
opening
doors
innovative
bioremediation
techniques
therapeutic
treatments
against
bacterial
diseases.
This
review
explores
intriguing
world
MBPs
emphasizes
role
resistance,
detoxification
homeostasis.
Furthermore,
metallochaperones
been
extensively
studied
using
metalloproteomic
methodologies
utilized
proteins.
study
also
provides
useful
information
interactions
between
these
different
MBPs,
advances
our
understanding
how
respond
Antibiotics,
Год журнала:
2024,
Номер
13(11), С. 1087 - 1087
Опубликована: Ноя. 14, 2024
Antimicrobial
resistance
(AMR)
is
a
serious
global
health
issue,
aggravated
by
antibiotic
overuse
and
misuse
in
human
medicine,
animal
care,
agriculture.
This
study
looks
at
the
different
mechanisms
that
drive
AMR,
such
as
environmental
contamination,
horizontal
gene
transfer,
selective
pressure,
well
severe
implications
of
AMR
for
health.
demonstrates
need
concerted
efforts
across
scientific,
healthcare,
agricultural,
policy
sectors
to
control
emergence
AMR.
Some
crucial
strategies
discussed
include
developing
antimicrobial
stewardship
(AMS)
programs,
encouraging
targeted
narrow-spectrum
use,
emphasizing
significance
strict
regulatory
frameworks
surveillance
systems,
like
Global
Resistance
Use
Surveillance
System
(GLASS)
Access,
Watch,
Reserve
(AWaRe)
classification.
also
emphasizes
national
international
action
plans
combating
promotes
One
Health
strategy,
which
unifies
environmental,
animal,
concludes
preventing
spread
maintaining
effectiveness
antibiotics
future
generations
requires
comprehensive,
multidisciplinary,
internationally
coordinated
strategy.
Frontiers in Synthetic Biology,
Год журнала:
2025,
Номер
2
Опубликована: Янв. 7, 2025
Developing
strategies
for
the
prevention
of
antimicrobial
resistance
genes
(ARG)
in
wastewater
treatment
facilities,
such
as
municipal
sewage
lagoons,
is
important
to
prevent
ARG
introduction
and
proliferation
environment.
While
previous
studies
have
shown
promising
results
reducing
ARGs
through
biological
phytoremediation
systems
like
Constructed
Wetlands,
underlying
mechanisms
impact
water
chemistry
on
reduction
remain
poorly
understood.
This
study
used
metagenomics
investigate
effect
three
different
treatments
microbial
community
resistome.
The
indicated
that
each
significantly
reduced
metal
(MRGs).
A
network
analysis
identified
eight
bacterial
genera
strongly
associated
with
genes,
six
which
belonged
phylum
Pseudomonadota
two
Campylobacteria.
Of
Pseudomonadota,
four
were
facultative
anaerobes.
strong
correlation
was
observed
between
iron
(Fe)
concentration
total
abundance
(
r
=
0.95),
well
(across
measured
metals)
0.93).
Additionally,
there
a
significant
Fe
0.86).
implies
high
concentrations
may
favor
ARG-harboring
bacteria
by
providing
an
electron
donor
anaerobic
respiration.
suggests
phytoextraction
metals,
including
Fe,
play
role
treated
columns.
These
findings
offer
valuable
insights
into
how
removal
can
effectively
reduce
levels
wastewater.
Sustainable Environment,
Год журнала:
2024,
Номер
10(1)
Опубликована: Март 6, 2024
Waste
management
is
one
of
the
most
pressing
environmental
issues
due
to
result
human
activities
with
changes
in
lifestyle
and
consumption
patterns.
To
combat
this,
waste
minimization
solutions
have
been
built
on
basis
hierarchy
so
as
procure
practical
value
from
product
source.
However,
efforts
taken
previous
stages
turned
out
be
uneconomical
resulted
immense
quantities
chemical
waste.
The
challenges
barriers
are
significant,
but
opportunities.
Therefore,
usage
marine
organisms
has
recommended
an
efficient
alternative
process
because
its
unique
attributes.
bacterial
communities
among
habitats
play
important
part
global
biogeochemical
cycle
their
diverse
metabolic
capacities.
Marine
microorganisms
biodegradation
processes
for
dissolving
a
broad
range
organic
contaminants,
either
individual
strains
or
members
microbial
consortia.
They
ability
degrade,
alter,
create
wide
compounds
created
naturally
by
man-made
processes.
These
actively
involved
nutrient
cycling
productivity
and,
therefore,
aid
balancing
ecosystem
managing
concentrations
pollutants.
Intense
research
through
all
these
years
gathered
that
crucial
role
production
non-toxic
biosurfactants
biopolymers.
Furthermore,
deeper
comprehension
harmful
heavy
metals
interact
microbes
led
suggestion
could
used
variety
ways
treat
contaminated
water
systems.
core
this
paper
reports
literature
degradation
wastes,
inorganic
wastes
wastewater
several
can
break
down
extract
toxic
substances
environment.
This
review
attempts
explore
potential
depth.
demonstrated
significance
novel
source
enzymes,
paving
promising
scope
industry
academia.
A
significant
fraction
not
identified,
enzyme
activity
studied
exploratory
limitations.
profiling
will
enable
us
observe
benefits
long
run.
Also,
emphasized
opportunities
outputs
acquired
bioeconomy
era.
Utilizing
resources
exposed
natural
products
may
present
biotechnological
applications.
also
provide
treatment
outcome
overcome
adverse
properties,
if
any,
deliver
effective
advance
use
