European Journal of General Practice,
Год журнала:
2024,
Номер
30(1)
Опубликована: Март 21, 2024
Periodontitis
is
a
chronic
inflammatory
non-communicable
disease
(NCD)
characterised
by
the
destruction
of
tooth-supporting
apparatus
(periodontium),
including
alveolar
bone,
presence
periodontal
pockets,
and
bleeding
on
probing.
Periodontology 2000,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 4, 2024
Abstract
Periodontal
diseases,
a
group
of
complex
conditions
marked
by
an
excessive
immune
response
and
periodontal
tissue
destruction,
are
global
health
concern.
Since
1990,
the
incidence
these
diseases
has
doubled,
with
Western
sub‐Saharan
Africa
experiencing
highest
burden.
Accurate
diagnosis
case
identification
crucial
for
understanding
etiology,
features
disease,
research,
treatment
prevention.
Modern
perspectives
on
disease
classification
based
commonality
among
those
affected.
However,
current
literature
is
often
plagued
methodological
inconsistencies
focused
mechanisms
in
European
populations.
Health
inequalities
low‐
middle‐income
countries
(LMICs)
exacerbated
challenges,
Africa,
Nigeria
specifically,
facing
unique
difficulties
such
as
clinical
personnel
shortages
limited
research
infrastructure.
This
review
explored
disparities
care
outcomes
African
We
highlighted
identified
factors
contributing
to
inequities
outcomes.
further
demonstrated
critical
need
inclusive
equitable
healthcare
practices
tailored
challenges
faced
diverse
populations
regions
resources.
Addressing
essential
ensuring
that
advancements
accessible
all,
thereby
improving
oral
general
health.
Periodontology 2000,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 8, 2025
Abstract
To
provide
a
comprehensive
and
updated
mapping
of
observational
studies
assessing
the
relationship
between
periodontitis
systemic
diseases
through
bibliometric
visual
analysis.
A
search
was
conducted
using
Web
Science
database,
covering
period
1989
to
2024.
The
Medical
Subject
Headings
(MeSH)
from
US
National
Library
Medicine
used
categorize
conditions,
focusing
on
terms
unrelated
stomatognathic
diseases.
analysis
included
keyword
co‐occurrence
mapping,
co‐authorship,
bibliographic
coupling,
co‐citation
Quality
indicators
such
as
silhouette
score,
modularity,
centrality
were
considered
assess
network's
quality.
research
strategy
identified
6106
records,
which
1519
met
inclusion
criteria.
revealed
that
46.73%
literature
topic
published
in
last
5
years
annual
publication
trend
peaked
2023.
Nutritional
&
Metabolic
Diseases
(
n
=
398),
Cardiovascular
335),
Female
Urogenital
Pregnancy
Complications
244),
Musculoskeletal
182)
most
representative
categories
associated
with
periodontitis.
co‐cited
journals
Journal
Periodontology
1412),
Clinical
1343),
Dental
Research
940),
2000
849).
USA,
China,
Brazil,
Sweden
countries
contributed
number
publications.
present
study
growing
evaluating
association
diseases,
highlighting
negative
impact
plethora
conditions
rising
translational
interest
this
relationship.
With
an
aging
population,
is
expected
affect
people
coming
decades,
presenting
significant
challenges
public
health.
Improved
knowledge
is,
therefore,
essential
enable
more
care,
preventive
strategies,
optimal
oral
health
for
patients
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(8), С. 4504 - 4504
Опубликована: Апрель 19, 2024
The
aim
of
this
comprehensive
review
is
to
summarize
recent
literature
on
associations
between
periodontitis
and
neurodegenerative
diseases,
explore
the
bidirectionality
provide
insights
into
plausible
pathogenesis.
For
purpose,
systematic
reviews
meta-analyses
from
PubMed,
Medline
EMBASE
were
considered.
Out
33
retrieved
papers,
6
articles
complying
with
inclusion
criteria
selected
discussed.
Additional
relevant
papers
for
pathogenesis
included.
Results
show
an
association
Alzheimer's
disease,
odds
ratios
3
5.
A
bidirectional
relationship
suspected.
Parkinson's
disease
(PD),
current
evidence
appears
be
weak,
although
poor
oral
health
PD
seem
correlated.
huge
knowledge
gap
was
identified.
mechanistic
link
diseases
interplay
periodontal
inflammation
neuroinflammation.
Three
pathways
are
hypothesized
in
literature,
i.e.,
humoral,
neuronal
cellular,
a
clear
role
pathogens,
such
as
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
13(9)
Опубликована: Янв. 21, 2024
Abstract
The
complex
preparation,
weak
wet
tissue
adhesion,
and
limited
biological
activity
of
traditional
oral
wound
dressings
usually
impede
their
efficient
treatment
healing
for
diabetic
mucosal
defects.
To
overcome
these
problems,
a
novel
hydrogel
adhesive
(named
CFT
hydrogel)
is
rapidly
constructed
using
one‐step
method
based
on
dual‐dynamic
covalent
cross‐linking.
Compared
with
the
commercial
patches,
shows
superior
in
vivo
(rat
tongue)
adhesion
performance.
Additionally,
exhibits
unique
acid‐responsive
properties,
thereby
facilitating
release
bioactive
molecule
tannic
acid
acidic
microenvironment.
And
series
vitro
experiments
substantiate
favorable
biocompatibility
bioactivity
properties
(including
antibacterial,
antioxidative,
anti‐inflammatory,
angiogenetic
effects)
exhibited
by
hydrogel.
Moreover,
conducted
rat
model
defects
demonstrate
that
significant
efficacy
protecting
against
wounds,
alleviating
inflammatory
reactions,
wound‐healing
process.
Taken
together,
this
study
provides
promising
comprehensive
therapeutic
option
great
potential
clinical
management
mucosa
patients.
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 6857 - 6893
Опубликована: Июль 1, 2024
Periodontitis
is
a
disease
of
inflammation
that
affects
the
tissues
supporting
periodontium.
It
triggered
by
an
immunological
reaction
gums
to
plaque,
which
leads
destruction
periodontal
attachment
structures.
one
most
commonly
recognized
dental
disorders
in
world
and
major
factor
loss
adult
teeth.
Scaling
root
planing
remain
crucial
for
managing
patients
with
persistent
periodontitis.
Nevertheless,
exclusive
reliance
on
mechanical
interventions
like
surgery,
extractions,
planning
insufficient
halt
progression
In
response
problem
bacterial
resistance,
some
researchers
are
committed
finding
alternative
therapies
antibiotics.
addition,
scholars
focus
new
materials
provide
powerful
microenvironment
tissue
regeneration
promote
osteogenic
repair.
Nanoparticles
possess
distinct
therapeutic
qualities,
including
exceptional
antibacterial,
anti-inflammatory,
antioxidant
properties,
immunomodulatory
capacities,
promotion
bone
ability,
made
them
can
be
used
treatment
However,
there
many
problems
limit
clinical
translation
nanoparticles,
such
as
toxic
accumulation
cells,
poor
correlation
between
vitro
vivo,
animal-to-human
transmissibility.
this
paper,
we
review
present
researches
nanoparticles
periodontitis
from
perspective
three
main
categories:
inorganic
organic
nanocomposites
(including
nanofibers,
hydrogels,
membranes).
The
aim
comprehensive
recent
update
nanoparticles-based
conclusion
section
summarizes
opportunities
challenges
design
Seminars in Orthodontics,
Год журнала:
2024,
Номер
30(2), С. 123 - 134
Опубликована: Янв. 11, 2024
Stage
IV
periodontitis
is
characterized,
apart
from
high
severity
/
complexity
(attachment
loss,
radiographic
bone
and
deep
probing
depths),
loss
of
multiple
teeth
or
alterations
the
masticatory
function.
Periodontitis
stage
patients
are
often
characterized
by
pathologic
tooth
migration,
drifting,
flaring,
including
posterior
bite
collapse,
secondary
occlusal
trauma.
These
act
as
factors
not
only
for
management
periodontitis,
but
also
prognosis
whole
dentition,
majority
these
present
malocclusions
that
require
interdisciplinary
treatment
with
orthodontics.
However,
complex
requires
coordination
between
periodontal
orthodontic
specialist,
while
needs
to
be
appropriately
adjusted
specificities
adult
periodontally-stable
severely
reduced
periodontium.
The
aim
paper
discuss
patients,
conditions
need
met
start,
treatment-related
considerations
pertaining
appliance
choice
mechanotherapy,
well
post-treatment
maintenance
protocols
ensure
long-term
stability
results.
Finally,
an
updated
systematic
review
meta-analysis
presented
summarizes
clinical
evidence
on
effect
combined
periodontal-orthodontic
pathological
migration.
American Journal of Primatology,
Год журнала:
2025,
Номер
87(2)
Опубликована: Фев. 1, 2025
ABSTRACT
This
review
article
provides
a
historical
summary
regarding
the
use,
value,
and
validity
of
nonhuman
primate
model
periodontal
disease.
The
information
provided
cites
results
features
naturally
occurring
periodontitis
in
various
species,
as
well
implementation
experimental
periodontitis.
Clinical
similarities
to
human
disease
are
discussed,
use
these
models
document
physiological
pathophysiological
tissue
changes
periodontium
related
initiation
progression
Additionally,
analytics
examination
characteristics
disease,
utility
primates
testing
describing
therapeutic
modalities
described.
As
represents
an
oral
microbiome
dysbiosis,
altered
similar
findings
condition.
then
local
systemic
host
responses
infection
array
species.
includes
attributes
innate
immunity,
acute
chronic
inflammation,
adaptive
immune
responses.
Finally,
extensive
is
presented
role
Macaca
mulatta
derived
from
Cayo
Santiago
community
evaluating
critical
biologic
details
initiation,
progression,
resolution.
unique
resource
afforded
capacity
relate
risk
expression
traits
age,
sex,
matriline
derivation
(e.g.,
heritability)
animals.
colony
continues
provide
preclinical
for
assessment
molecular
aspects
process
that
can
lead
both
new
targets
therapeutics
consideration
vaccine
approaches
preventing
and/or
treating
this
global
