AIP conference proceedings, Год журнала: 2023, Номер 2963, С. 020025 - 020025
Опубликована: Янв. 1, 2023
Язык: Английский
AIP conference proceedings, Год журнала: 2023, Номер 2963, С. 020025 - 020025
Опубликована: Янв. 1, 2023
Язык: Английский
AIP conference proceedings, Год журнала: 2023, Номер 2822, С. 020008 - 020008
Опубликована: Янв. 1, 2023
Язык: Английский
Процитировано
3Journal of Applied Engineering and Technological Science (JAETS), Год журнала: 2023, Номер 5(1), С. 150 - 169
Опубликована: Дек. 10, 2023
Oral cancer is the eighth most common type of in world. Every year, 130,000 people India die from mouth cancer. Getting a diagnosis clinical exam by skilled doctors and biopsy takes time. When problem found early, it always easier to treat. The primary goal this work recognise disease-affected oral regions given image classify disorder. This study employs unique Deep Learning algorithms detect location areas. effective feature extraction techniques, including appearance patter-based features. Following extraction, Bee Pulse Couple Neural Network (BeePCNN) algorithm used choose best feature. Finally, these attributes. An innovative FGPSOCNN reduces computational complexity CNN. On an additional real-time data set Arthi Scan Hospital, secondary evaluation conducted. experimental results indicate that performs better than existing methods.
Язык: Английский
Процитировано
3International Journal of Dentistry and Oral Science, Год журнала: 2021, Номер unknown, С. 4579 - 4582
Опубликована: Сен. 23, 2021
tachment level and also bad breath chronic inflammation.The primary etiology of gingivitis is plaque, but there are several aggravating [3] factors including habits like smoking, stress, genetic factors, systemic diseases hormonal distress [4][5][6][7][8][9][10][11][12].Untreated will cause periodontitis, which manifests as increased pocket depth, recession, furcation involvement, mobility, bone loss [13][14][15][16][17].
Язык: Английский
Процитировано
7Oral Diseases, Год журнала: 2023, Номер unknown
Опубликована: Янв. 27, 2023
In order to predict the patients' prognosis with tongue squamous cell carcinoma (SCC), this study set out develop a clinically useful and trustworthy prognostic nomogram.
Язык: Английский
Процитировано
2PeerJ, Год журнала: 2023, Номер 11, С. e15154 - e15154
Опубликована: Апрель 19, 2023
Background The sirtuins (SIRTs) family is a nicotinamide adenine dinucleotide (NAD+) of dependent deacetylases, which includes SIRT1-7. This related to the development and progression various tumors. However, comprehensive analysis role SIRTs in clear cell renal carcinoma (ccRCC) still lacking, there are few reports on inhibitory SIRT5 ccRCC. Methods We used immunohistochemical analysis, several bioinformatic databases perform an integrated expression prognostic value other SIRT members ccRCC along with associated immune infiltration. These include TIMER, THPA, culture, UALCAN, cBioPortal, WebGestalt, Metascape, DiseaseMeth, STRING database, Cytoscape. Results protein SIRT1, 2, 3, 6, 7 were upregulated for Human Protein Atlas whereas SIRT4 was decreased. based tumor stage, grade followed similar trend. Kaplan–Meier showed that high positively better overall survival (OS), SIRT6 SIRT7 worse OS. Further, SIRT3 relapse-free (RFS), RFS. To explore mechanism underlying function ccRCC, we also functional enrichment relationship between infiltrating cells seven results members, particularly SIRT5, correlated infiltration some important cells. significantly lower tissue compared normal negatively age patient individual stages, grades. In human samples, strong IHC staining displayed adjacent than tissues. Conclusion may be marker novel strategy treatment
Язык: Английский
Процитировано
2Journal of Population Therapeutics and Clinical Pharmacology, Год журнала: 2023, Номер 30(14)
Опубликована: Янв. 1, 2023
Aim: To evaluate the root canal cleanliness after retreatment with ProTaper Universal and Solite RS rotary file system.Materials Methods: Twenty extracted single-rooted premolar teeth were selected.The canals enlarged nickel-titanium (NiTi) files, filled gutta-percha sealer, randomly divided into two experimental groups.The filling materials removed either one of following systems: or RS.No solvent was used for removal gutta percha.Teeth sectioned longitudinal assessed under microscope.Results: Both instrumentation techniques left obturating material in at apical, coronal middle third.There no significant difference both groups regards to all three levels (p>0.05). Conclusion:Based on findings our vitro study conducted mandibular premolars single roots, we can conclude that instruments inside canal.The evaluation coronal, middle, apical thirds did not reveal any variations remaining between type material.
Язык: Английский
Процитировано
2Human & Experimental Toxicology, Год журнала: 2021, Номер 40(12_suppl), С. S423 - S433
Опубликована: Сен. 29, 2021
Sesamol is the main constituent of sesame seed oil and obtained from Sesamum indicum. Oral squamous cell carcinoma (OSCC) one most common neoplasms affecting oral cavity. In this study, we investigated cytotoxic potentials sesamol on human (SCC-25) cells. Human cells were treated with different concentrations (62.5, 125, 250 μM/mL) for 24 h. Cytotoxicity was analyzed by 3- (4, 5- dimethylthiazol -2- yl) -2, 5-diphenyltetrazolium bromide (MTT) assay. Intracellular reactive oxygen species (ROS) expression dichloro-dihydro-fluorescein diacetate Apoptosis-related morphology acridine orange/ethidium staining. Caspase-9 confocal microscopic double immunofluorescence Mitochondrial apoptosis-related markers are using qPCR. treatment caused a significant effect in OSCC Sesamol-induced associated intracellular ROS generation. treatments induced increase early late apoptotic This also caspase-9 downregulation Harvey rat sarcoma viral oncogene homolog (HRAS) at protein gene levels. modulates intrinsic marker Overall results confirm anti-cancer potential it seems to be promising candidate OSCC.
Язык: Английский
Процитировано
5International Journal of Dentistry and Oral Science, Год журнала: 2021, Номер unknown, С. 4624 - 4627
Опубликована: Сен. 23, 2021
tors including age, gender, smoking, stress, socioeconomic status, genetic factors, systemic diseases and hormonal changes [1][2][3][4][5][6][7][8][9].If the condition is left untreated, it leads to increase in pocket depth, gingival recession, clinical attachment loss, bone furcation involvement, pathological migration tooth mobility eventually leading loss [10][11][12][13][14][15].The management of periodontitis involves scaling root planning followed by flap surgery.In periodontal surgery, most
Язык: Английский
Процитировано
5International Journal of Dentistry and Oral Science, Год журнала: 2014, Номер unknown, С. 4588 - 4592
Опубликована: Янв. 1, 2014
genetic factors, smoking, stress, hormones [8][9][10][11]
Язык: Английский
Процитировано
4International Journal of Dentistry and Oral Science, Год журнала: 2021, Номер unknown, С. 4597 - 4601
Опубликована: Сен. 23, 2021
include loss of attachment, alveolar bone and teeth, extending beyond the local level to produce systemic effects, increases inflammation [1][2][3][4][5][6].Even though primary aetiology periodontal disease is bacterial plaque, aggravated by various risk factors including age, diseases, gender, genetic factors, smoking, stress, hormones [7][8][9][10][11][12][13][14][15][16][17][18].Gender-based heterogeneity in has been wit-
Язык: Английский
Процитировано
4