Oral Diseases,
Год журнала:
2022,
Номер
29(7), С. 2624 - 2637
Опубликована: Ноя. 13, 2022
Recent
new
terminologies
have
been
proposed
for
lesions
in
the
sphere
of
oral
lichen
planus
(OLP)
that
theoretically
present
unique
aetiological,
clinical,
prognostic
or
management
characteristics
different
from
those
so-called
typical
forms
OLP.
We
aimed
to
critically
analyse
what
concepts
and
related
OLP
should
we
accept
based
on
available
evidence.
A
review
literature
was
carried
out
order
New
include
lichenoid
lesions;
contact
reactions,
drug
reactions
context
graft-versus-host
disease;
chronic
ulcerative
stomatitis;
pemphigoid;
some
are
difficult
categorise,
such
as
with
features
proliferative
verrucous
leukoplakia
upper
labial
mucosa.
multidisciplinary,
multicontinent
working
group
has
recently
published
a
guideline
recommendations
modifying
definitions
associated
disease,
among
which
reasoned,
evidence-based
justification
change
is
considered
essential.
An
in-depth
analysis
newly
terms
OLP-related
shows
many
them
not
justified.
In
this
paper,
set
our
position
basis
existing
evidence
appropriateness
use
these
terms.
Histopathology,
Год журнала:
2024,
Номер
85(1), С. 40 - 50
Опубликована: Март 18, 2024
Aims
Oral
epithelial
dysplasia
(OED)
often
exhibits
a
lymphocytic/lichenoid
immune
response
(LIR),
imparting
histological
resemblance
to
lichenoid
mucositis
and
rendering
diagnosis
challenging.
The
clinical
appearances
of
OED
inflammatory
processes
are
generally
divergent,
presenting
as
well‐demarcated
hyperkeratotic
plaques
diffuse
white
and/or
red
mucosal
change
with
variably
prominent
Wickham
striae,
respectively.
To
date,
clinicopathological
characterisation
LIR,
including
clinical/gross
appearance,
has
not
been
depicted.
Methods
results
Cases
solitary
LIR
for
which
photograph
was
available
were
identified
in
the
authors’
institutional
files.
Clinical
features
documented.
In
44
cases,
mild
(19
44,
43.2%),
moderate
43.2%)
severe
(six
13.6%).
Clinically/grossly,
all
cases
(100.0%),
presented
lacking
white‐and‐red
or
striae.
Histologically,
exhibited
numerous
‘lichenoid’
beyond
lymphocytic
band
superficial
lamina
propria,
including:
leucocyte
transmigration
(38
86.4%),
spongiosis
(37
84.1%),
Civatte/colloid
bodies
(36
81.8%),
basal
cell
degeneration
(29
45,
65.9%),
sawtooth
rete
ridges
(11
25.0%)
subepithelial
clefting
(7
15.9%).
Conclusions
Virtually
any
feature
may
be
seen
representing
significant
diagnostic
pitfall.
typical
appearance
is
plaque,
characteristic
keratinising
devoid
features.
This
suggests
that
pathologist
access
photographs
during
interpretation
biopsied
lesions,
represents
opportunity
perform
gross
examination
disease
process,
reduce
interobserver
variability
improve
accuracy
this
challenging
differential
diagnosis.
Oral Diseases,
Год журнала:
2022,
Номер
29(7), С. 2624 - 2637
Опубликована: Ноя. 13, 2022
Recent
new
terminologies
have
been
proposed
for
lesions
in
the
sphere
of
oral
lichen
planus
(OLP)
that
theoretically
present
unique
aetiological,
clinical,
prognostic
or
management
characteristics
different
from
those
so-called
typical
forms
OLP.
We
aimed
to
critically
analyse
what
concepts
and
related
OLP
should
we
accept
based
on
available
evidence.
A
review
literature
was
carried
out
order
New
include
lichenoid
lesions;
contact
reactions,
drug
reactions
context
graft-versus-host
disease;
chronic
ulcerative
stomatitis;
pemphigoid;
some
are
difficult
categorise,
such
as
with
features
proliferative
verrucous
leukoplakia
upper
labial
mucosa.
multidisciplinary,
multicontinent
working
group
has
recently
published
a
guideline
recommendations
modifying
definitions
associated
disease,
among
which
reasoned,
evidence-based
justification
change
is
considered
essential.
An
in-depth
analysis
newly
terms
OLP-related
shows
many
them
not
justified.
In
this
paper,
set
our
position
basis
existing
evidence
appropriateness
use
these
terms.
